Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Zigor Aira"'
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0194534 (2018)
Fibromyalgia syndrome (FMS) is a highly prevalent, chronic musculoskeletal condition characterized by widespread pain and evoked pain at tender points. This study evaluated various aspects of body awareness in a sample of 14 women with FMS and 13 hea
Externí odkaz:
https://doaj.org/article/d2ee5edabf0d4bb597912efaf440bfd1
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162416 (2016)
Dopamine can influence NMDA receptor function and regulate glutamate-triggered long-term changes in synaptic strength in several regions of the CNS. In spinal cord, regulation of the threshold of synaptic plasticity may determine the proneness to und
Externí odkaz:
https://doaj.org/article/ad69dcc9781b4fa291babe9a887465e5
Autor:
Aitziber Mendiguren, Jon Jatsu Azkue, Zigor Aira, María Carmen Medrano, Patricia Pablos, Joseba Pineda, Itsaso Buesa, María Teresa Santamarta
Publikováno v:
British Journal of Pharmacology. 174:2758-2772
Background and Purpose Regulation of μ receptor dynamics such as its trafficking is a possible mechanism underlying opioid tolerance that contributes to inefficient recycling of opioid responses. We aimed to characterize the functional turnover of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ed6ecbef6bacf5e04850e660ffe013d
https://doi.org/10.1111/bph.13901
https://doi.org/10.1111/bph.13901
Publikováno v:
The Journal of Neuroscience. 36:5661-5673
The current study reports on a synaptic mechanism through which D1-like receptors (D1LRs) modulate spinal nociception and plasticity by regulating activation of the μ-opioid receptor (MOR).D1LR stimulation with agonist SKF 38393 concentration-depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691507e31bf239d7fdab2c14565269d9
https://doi.org/10.1523/jneurosci.2469-15.2016
https://doi.org/10.1523/jneurosci.2469-15.2016
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0194534 (2018)
PLoS ONE
Addi. Archivo Digital para la Docencia y la Investigación
instname
PLoS ONE
Addi. Archivo Digital para la Docencia y la Investigación
instname
Fibromyalgia syndrome (FMS) is a highly prevalent, chronic musculoskeletal condition characterized by widespread pain and evoked pain at tender points. This study evaluated various aspects of body awareness in a sample of 14 women with FMS and 13 hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6892a3230b878145c7d18bdeb0167cd5
http://europepmc.org/articles/PMC5889164?pdf=render
http://europepmc.org/articles/PMC5889164?pdf=render
Publikováno v:
Brain Research. 1594:190-203
Interactions of opioid receptors with other receptor families can be made use of to improve analgesia and reduce adverse effects of opioid analgesics. We investigated interactions of the α2-adrenergic receptor (α2AR) with opioid receptors of the mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94bdc673bd2228679916171d9247fe0f
https://doi.org/10.1016/j.brainres.2014.11.009
https://doi.org/10.1016/j.brainres.2014.11.009
Autor:
María Carmen, Medrano, María Teresa, Santamarta, Patricia, Pablos, Zigor, Aira, Itsaso, Buesa, Jon Jatsu, Azkue, Aitziber, Mendiguren, Joseba, Pineda
Publikováno v:
British journal of pharmacology. 174(16)
Regulation of μ receptor dynamics such as its trafficking is a possible mechanism underlying opioid tolerance that contributes to inefficient recycling of opioid responses. We aimed to characterize the functional turnover of μ receptors in the nora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7da5250362ce5dc5778d7208a640d993
https://pubmed.ncbi.nlm.nih.gov/28589556
https://pubmed.ncbi.nlm.nih.gov/28589556
Publikováno v:
Neuroscience letters. 618
Activation of the N-methyl-d-aspartate receptor (NMDAR) in dorsal horn neurons is recognized as a fundamental mechanism of central sensitization and pathologic pain. This study assessed the influence of dopaminergic, D1-like receptor-mediated input t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eaa82e46e168067b729a3c6d0af8543
https://pubmed.ncbi.nlm.nih.gov/26957228
https://pubmed.ncbi.nlm.nih.gov/26957228
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
instname
PLoS ONE, Vol 11, Iss 9, p e0162416 (2016)
PLoS ONE
instname
PLoS ONE, Vol 11, Iss 9, p e0162416 (2016)
PLoS ONE
Dopamine can influence NMDA receptor function and regulate glutamate-triggered long-term changes in synaptic strength in several regions of the CNS. In spinal cord, regulation of the threshold of synaptic plasticity may determine the proneness to und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79052472093cce78100b383c0e89d23
http://hdl.handle.net/10810/32527
http://hdl.handle.net/10810/32527
Autor:
Janire Mingo, Nahia Mendiable, Diego Rada, Mónica Gallego, Juan Bilbao, Itsaso Buesa, Gontzal García del Caño, Zigor Aira, Jon Jatsu Azkue, Manfred Zimmermann
Publikováno v:
The Journal of Neuroscience. 32:13568-13581
Emerging evidence implicates serotonergic descending facilitatory pathways from the brainstem to the spinal cord in the maintenance of pathologic pain. Upregulation of the serotonin receptor 2A (5-HT2AR) in dorsal horn neurons promotes spinal hyperex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8223249d4133b16e82d8b97ec088b05c
https://doi.org/10.1523/jneurosci.1364-12.2012
https://doi.org/10.1523/jneurosci.1364-12.2012