Synthesis and in vitro antitumor activity of novel alkenyl derivatives of pyridoxine, bioisosteric analogs of feruloyl methane.

Autor: Pavelyev RS; Kazan (Volga region) Federal University, Kremlyovskaya 18, 420008 Kazan, Russia., Bondar OV; Kazan (Volga region) Federal University, Kremlyovskaya 18, 420008 Kazan, Russia., Nguyen TNT; Kazan (Volga region) Federal University, Kremlyovskaya 18, 420008 Kazan, Russia., Ziganshina AA; Kazan (Volga region) Federal University, Kremlyovskaya 18, 420008 Kazan, Russia., Al Farroukh M; Kazan (Volga region) Federal University, Kremlyovskaya 18, 420008 Kazan, Russia., Karwt R; Kazan (Volga region) Federal University, Kremlyovskaya 18, 420008 Kazan, Russia., Alekbaeva GD; Kazan (Volga region) Federal University, Kremlyovskaya 18, 420008 Kazan, Russia., Pugachev MV; Kazan (Volga region) Federal University, Kremlyovskaya 18, 420008 Kazan, Russia., Yamaleeva ZR; A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov Str. 8, Kazan 420088, Russia., Kataeva ON; A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center of RAS, Arbuzov Str. 8, Kazan 420088, Russia., Balakin KV; Kazan (Volga region) Federal University, Kremlyovskaya 18, 420008 Kazan, Russia; I.M. Sechenov First Moscow State Medical University, Trubetskaya 8, Bldg. 2, 119991 Moscow, Russia., Shtyrlin YG; Kazan (Volga region) Federal University, Kremlyovskaya 18, 420008 Kazan, Russia. Electronic address: yurii.shtyrlin@gmail.com.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2018 Dec 01; Vol. 26 (22), pp. 5824-5837. Date of Electronic Publication: 2018 Oct 27.

Synthesis and antitumor activity of novel pyridoxine-based structural analogs of saccharumoside-B.

Autor: Pugachev, Mikhail V., Agafonova, Maria N., Bastrikova, Oksana A., Gnezdilov, Oleg I., Nikishova, Tatyana V., Balakin, Konstantin V., Shtyrlin, Yurii G.

Publikováno v: Medicinal Chemistry Research; May2021, Vol. 30 Issue 5, p1139-1150, 12p