Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Zifeng Cui"'
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Gut microbiome dysbiosis is associated with gestational diabetes mellitus (GDM), and its modulation represents a promising approach for enhancing glycemic control. In this study, we aimed to discover specific alterations in the gut microbiom
Externí odkaz:
https://doaj.org/article/a44b08d04b544e43bb5eb67fb28a6a5f
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Gestational diabetes mellitus (GDM) is characterized by insulin resistance and low-grade inflammation, and most studies have demonstrated gut dysbiosis in GDM pregnancies. Overall, they were manifested as a reduction in microbiome diversity
Externí odkaz:
https://doaj.org/article/02ce046b306641afb9d194deafd66720
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109900- (2024)
Summary: Type 2 diabetes mellitus (T2DM) represents a common complication during pregnancy that affects fetoplacental development. We demonstrated the existence of impaired trophoblast syncytialization under hyperglycemic conditions. However, the exa
Externí odkaz:
https://doaj.org/article/4dc68c2c35c34a36b2ee004c3630115c
Publikováno v:
Biomedical Papers, Vol 166, Iss 3, Pp 280-289 (2022)
Background. Oral squamous cell carcinoma (OSCC) severely affects the quality of life and the 5-year survival rate is low. Exploring the potential miRNA-mRNA regulatory network and analyzing hub genes and clinical data can provide a theoretical basis
Externí odkaz:
https://doaj.org/article/fd10e445ae1542aab68c0ed0681b9131
Publikováno v:
BMC Oral Health, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Oral squamous cell carcinoma (OSCC) is the most common neck and head malignancies, and the prognosis is not good. Studies shown that the long non-coding RNA (lncRNA) TFAP2A-AS1 is involved in the progression of multiple cancers. H
Externí odkaz:
https://doaj.org/article/4d65277e13af4473a5dc1dc0844c8096
Autor:
Rui Tian, Jiashuo Liu, Weiwen Fan, Rui Li, Zifeng Cui, Zhuang Jin, Zhaoyue Huang, Hongxian Xie, Lifang Li, Zheying Huang, Zheng Hu, Ping Zhou, Xun Tian
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 171-179 (2022)
A genome editing tool targeting the high-risk human papillomavirus (HPV) oncogene is a promising therapeutic strategy to treat HPV-related cervical cancer. To improve gene knockout efficiency, we developed a gene knockout chain reaction (GKCR) method
Externí odkaz:
https://doaj.org/article/6644771669824452940aa99c6d33b294
Autor:
Zifeng Cui, Rui Tian, Zhaoyue Huang, Zhuang Jin, Lifang Li, Jiashuo Liu, Zheying Huang, Hongxian Xie, Dan Liu, Haiyan Mo, Rong Zhou, Bin Lang, Bo Meng, Haiyan Weng, Zheng Hu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Gene editing tools have tremendous potential for biomedical and basic research. Here the authors report a Cas9 from Faecalibaculum rodentium (FrCas9) that achieves efficient and specific gene editing in human cells with a NNTA palindrome PAMs for tar
Externí odkaz:
https://doaj.org/article/5a3b8d6c478f465f82c1d544cc82ce2c
Autor:
Zifeng Cui, Hui Liu, Hongfeng Zhang, Zhaoyue Huang, Rui Tian, Lifang Li, Weiwen Fan, Yili Chen, Lijie Chen, Sen Zhang, Bhudev C. Das, Konstantin Severinov, Inga Isabel Hitzeroth, Priya Ranjan Debata, Zhuang Jin, Jiashuo Liu, Zheying Huang, Weiling Xie, Hongxian Xie, Bin Lang, Ji Ma, Haiyan Weng, Xun Tian, Zheng Hu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 1466-1478 (2021)
Zinc-finger nucleases (ZFNs), transcription activator-like endonucleases (TALENs), and CRISPR-associated Cas9 endonucleases are three major generations of genome editing tools. However, no parallel comparison about the efficiencies and off-target act
Externí odkaz:
https://doaj.org/article/2f11fed289fb4cdd859d753a95202f12
Autor:
Shixiong Peng, Jinhang Wang, Yanping Chen, Naiheng Hei, Jianguang Zhao, Xinjuan Wu, Zifeng Cui
Publikováno v:
European Journal of Inflammation, Vol 20 (2022)
To detect the expression, prognostic value, and possible effects of epithelial cell transforming sequence 2 (ECT2) and E2F1 in patients with oral squamous cell carcinoma (OSCC). Seventy subjects hospitalized for OSCC surgical treatment in the Fourth
Externí odkaz:
https://doaj.org/article/9568a888561f458fa2b91d067cb4c7d1
Autor:
Canbiao Wu, Xiaofang Guo, Mengyuan Li, Jingxian Shen, Xiayu Fu, Qingyu Xie, Zeliang Hou, Manman Zhai, Xiaofan Qiu, Zifeng Cui, Hongxian Xie, Pengmin Qin, Xuchu Weng, Zheng Hu, Jiuxing Liang
Publikováno v:
BMC Ecology and Evolution, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background The hepatitis B virus (HBV) is one of the main causes of viral hepatitis and liver cancer. HBV integration is one of the key steps in the virus-promoted malignant transformation. Results An attention-based deep learning model, Dee
Externí odkaz:
https://doaj.org/article/cb44f2c3dbe64691b8ecc84e9532b230