Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Zienab Saeed"'
Autor:
Elias Matouk, Marian Hajduch, Zienab Saeed, Gabriella Wojewodka, Claudine Guilbault, Danuta Radzioch, Juan B. De Sanctis
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 41:100-106
Patients with cystic fibrosis (CF) and Cftr-knockout mice (CF mice) display an imbalance in fatty acids, with high arachidonic acid (AA) and low docosahexaenoic acid (DHA) concentrations. Our recent studies demonstrated defects in another class of li
Autor:
Claudine Guilbault, Danuta Radzioch, Juan B. De Sanctis, René St-Arnaud, Dominique Marion, Jennifer Henri, Zienab Saeed
Publikováno v:
Journal of Cystic Fibrosis. 7:222-230
Background The most recently described phenotype associated with Cystic Fibrosis (CF) is reduced bone mineral density which results in osteopenia and osteoporosis. The etiology of the early onset of osteoporosis in CF patients has remained to be esta
Autor:
Thomas A. A. Skinner, Danuta Radzioch, Claudine Guilbault, Zienab Saeed, Stan Kubow, Juan B. De Sanctis, Elias Matouk, Gabriella Wojewodka, Marian Hajduch, Larry C. Lands, Regina Maria Vilela, Claude Lachance
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 38:47-56
Chronic and persistent lung infections cause the majority of morbidity and mortality in patients with cystic fibrosis (CF). Galactosyl ceramide has been previously shown to be involved in Pseudomonas internalization. Therefore, we assessed ceramide l
Publikováno v:
Current Pharmaceutical Design. 13:3252-3263
Before the cloning of the CFTR gene in 1989, there were relatively few treatment options for the many phenotypes associated with cystic fibrosis (CF). The advancement of research in areas such as immunology, molecular biology and pharmacology have pr
Publikováno v:
American journal of respiratory cell and molecular biology. 36(1)
Animal models of cystic fibrosis (CF) are powerful tools that enable the study of the mechanisms and complexities of human disease. Murine models have several intrinsic advantages compared with other animal models, including lower cost, maintenance,
Autor:
Jaroslav P. Novak, Marie-Christine Guiot, Marie-Linda Boghdady, Thomas J. Hudson, Danuta Radzioch, Zienab Saeed, Claudine Guilbault, Patricia Martin
Publikováno v:
Physiological genomics. 25(2)
Cystic fibrosis (CF) is caused by a defect in the CF transmembrane conductance regulator (CFTR) protein that functions as a chloride channel. Dysfunction of the CFTR protein results in salty sweat, pancreatic insufficiency, intestinal obstruction, ma
Autor:
Claudine Guilbault, Marian Hajduch, Zienab Saeed, Gabriella Wojewodka, Danuta Radzioch, J.B. De Sanctis, Elias Matouk
Publikováno v:
Journal of Cystic Fibrosis. 7:S28