Cellular and genetic models of H6PDH and 11β-HSD1 function in skeletal muscle

Autor: Zielinska, AE, Fletcher, RS, Sherlock, M, Doig, CL, Lavery, GG

Glucocorticoids are important for skeletal muscle energy metabolism, regulating glucose utilization, insulin sensitivity, and muscle mass. Nicotinamide adenine dinucleotide phosphate‐dependent 11β‐hydroxysteroid dehydrogenase type 1 (11β‐HSD1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::c5da1f1ea636a9f85b78ad0156ce5cc9
https://irep.ntu.ac.uk/id/eprint/38197/1/1215258_Doig.pdf

SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study.

Autor: Shields A; Clinical Immunology Service, University of Birmingham College of Medical and Dental Sciences, Birmingham, UK.; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Faustini SE; Clinical Immunology Service, University of Birmingham College of Medical and Dental Sciences, Birmingham, UK., Perez-Toledo M; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Jossi S; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Aldera E; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Allen JD; School of Biological Sciences, University of Southampton, Southampton, UK., Al-Taei S; Clinical Immunology Service, University of Birmingham College of Medical and Dental Sciences, Birmingham, UK., Backhouse C; Clinical Immunology Service, University of Birmingham College of Medical and Dental Sciences, Birmingham, UK., Bosworth A; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Dunbar LA; Clinical Immunology Service, University of Birmingham College of Medical and Dental Sciences, Birmingham, UK., Ebanks D; Clinical Immunology Service, University of Birmingham College of Medical and Dental Sciences, Birmingham, UK., Emmanuel B; Clinical Immunology Service, University of Birmingham College of Medical and Dental Sciences, Birmingham, UK., Garvey M; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Gray J; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Kidd IM; Public Health England Midlands and East Region, Birmingham, UK., McGinnell G; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., McLoughlin DE; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK., Morley G; Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK., O'Neill J; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Papakonstantinou D; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Pickles O; Surgical Research Laboratory, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK., Poxon C; Surgical Research Laboratory, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK., Richter M; Clinical Immunology Service, University of Birmingham College of Medical and Dental Sciences, Birmingham, UK., Walker EM; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Wanigasooriya K; Surgical Research Laboratory, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK., Watanabe Y; School of Biological Sciences, University of Southampton, Southampton, UK.; Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford, UK., Whalley C; Surgical Research Laboratory, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK., Zielinska AE; Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK., Crispin M; School of Biological Sciences, University of Southampton, Southampton, UK., Wraith DC; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.; University Hospitals Birmingham NHS Foundation Trust and University of Birmingham, NIHR Biomedical Research Centre, Birmingham, UK., Beggs AD; Surgical Research Laboratory, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK., Cunningham AF; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Drayson MT; Clinical Immunology Service, University of Birmingham College of Medical and Dental Sciences, Birmingham, UK.; University Hospitals Birmingham NHS Foundation Trust and University of Birmingham, NIHR Biomedical Research Centre, Birmingham, UK., Richter AG; Clinical Immunology Service, University of Birmingham College of Medical and Dental Sciences, Birmingham, UK a.g.richter@bham.ac.uk.; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

Publikováno v: Thorax [Thorax] 2020 Dec; Vol. 75 (12), pp. 1089-1094. Date of Electronic Publication: 2020 Sep 11.

Induction of the nicotinamide riboside kinase NAD ⁺ salvage pathway in a model of sarcoplasmic reticulum dysfunction.

Autor: Doig CL; Institute of Metabolism and Systems Research, University of Birmingham, 2nd Floor IBR Tower, Edgbaston, Birmingham, B15 2TT, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Zielinska AE; Institute of Metabolism and Systems Research, University of Birmingham, 2nd Floor IBR Tower, Edgbaston, Birmingham, B15 2TT, UK., Fletcher RS; Institute of Metabolism and Systems Research, University of Birmingham, 2nd Floor IBR Tower, Edgbaston, Birmingham, B15 2TT, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Oakey LA; Institute of Metabolism and Systems Research, University of Birmingham, 2nd Floor IBR Tower, Edgbaston, Birmingham, B15 2TT, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Elhassan YS; Institute of Metabolism and Systems Research, University of Birmingham, 2nd Floor IBR Tower, Edgbaston, Birmingham, B15 2TT, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Garten A; Institute of Metabolism and Systems Research, University of Birmingham, 2nd Floor IBR Tower, Edgbaston, Birmingham, B15 2TT, UK., Cartwright D; Institute of Metabolism and Systems Research, University of Birmingham, 2nd Floor IBR Tower, Edgbaston, Birmingham, B15 2TT, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Heising S; Institute of Metabolism and Systems Research, University of Birmingham, 2nd Floor IBR Tower, Edgbaston, Birmingham, B15 2TT, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Alsheri A; Strathclyde Institute of Pharmacy and Medical Sciences, Hamnett Wing John Arbuthnott Building, Glasgow, G4 0RE, UK., Watson DG; Strathclyde Institute of Pharmacy and Medical Sciences, Hamnett Wing John Arbuthnott Building, Glasgow, G4 0RE, UK., Prehn C; Research Unit of Molecular Endocrinology and Metabolism, Helmholtz Zentrum Munchen GmbH, Ingolstadter Landstrasse 1, D-85764, Neuherberg, Germany.; Lehrstuhl für Experimentelle Genetik, Technische Universität München, Freising, Germany.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore., Adamski J; Research Unit of Molecular Endocrinology and Metabolism, Helmholtz Zentrum Munchen GmbH, Ingolstadter Landstrasse 1, D-85764, Neuherberg, Germany.; Lehrstuhl für Experimentelle Genetik, Technische Universität München, Freising, Germany.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117593, Singapore., Tennant DA; Institute of Metabolism and Systems Research, University of Birmingham, 2nd Floor IBR Tower, Edgbaston, Birmingham, B15 2TT, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Lavery GG; Institute of Metabolism and Systems Research, University of Birmingham, 2nd Floor IBR Tower, Edgbaston, Birmingham, B15 2TT, UK. g.g.lavery@bham.ac.uk.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK. g.g.lavery@bham.ac.uk.; MRC-ARUK Centre for Musculoskeletal Ageing Research, University of Birmingham, Birmingham, UK. g.g.lavery@bham.ac.uk.

Publikováno v: Skeletal muscle [Skelet Muscle] 2020 Feb 19; Vol. 10 (1), pp. 5. Date of Electronic Publication: 2020 Feb 19.

Cellular and genetic models of H6PDH and 11β-HSD1 function in skeletal muscle.

Autor: Zielinska AE; Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK., Fletcher RS; Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Sherlock M; Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK., Doig CL; Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK., Lavery GG; Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK.

Publikováno v: Cell biochemistry and function [Cell Biochem Funct] 2017 Jul; Vol. 35 (5), pp. 269-277.

Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1.

Autor: Meyer A; Swiss Center for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Vuorinen A, Zielinska AE, Strajhar P, Lavery GG, Schuster D, Odermatt A

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2013 Sep; Vol. 41 (9), pp. 1671-8. Date of Electronic Publication: 2013 Jun 26.