Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Zied Landoulsi"'
Autor:
Velma T. E. Aho, Matthias Klee, Zied Landoulsi, Anna Heintz-Buschart, Lukas Pavelka, Anja K. Leist, Rejko Krüger, Patrick May, Paul Wilmes, on behalf of the NCER-PD Consortium
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-6 (2024)
Abstract Gut microbiome differences between people with Parkinson’s disease (PD) and control subjects without Parkinsonism are widely reported, but potential alterations related to PD with mild cognitive impairment (MCI) have yet to be comprehensiv
Externí odkaz:
https://doaj.org/article/897dee69227047e585ed34f6bcedcc9f
Autor:
Sinthuja Pachchek, Zied Landoulsi, Lukas Pavelka, Claudia Schulte, Elena Buena-Atienza, Caspar Gross, Ann-Kathrin Hauser, Dheeraj Reddy Bobbili, Nicolas Casadei, Patrick May, Rejko Krüger, on behalf of the NCER-PD Consortium
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Heterozygous variants in the glucocerebrosidase GBA1 gene are an increasingly recognized risk factor for Parkinson’s disease (PD). Due to the GBAP1 pseudogene, which shares 96% sequence homology with the GBA1 coding region, accurate varian
Externí odkaz:
https://doaj.org/article/7718d5c32af844e6882c7b60f9c51e58
Autor:
Patrycja Mulica, Carmen Venegas, Zied Landoulsi, Katja Badanjak, Sylvie Delcambre, Maria Tziortziou, Soraya Hezzaz, Jenny Ghelfi, Semra Smajic, Jens Schwamborn, Rejko Krüger, Paul Antony, Patrick May, Enrico Glaab, Anne Grünewald, Sandro L. Pereira
Publikováno v:
Biological Procedures Online, Vol 25, Iss 1, Pp 1-14 (2023)
Abstract Background Astrocytes have recently gained attention as key contributors to the pathogenesis of neurodegenerative disorders including Parkinson’s disease. To investigate human astrocytes in vitro, numerous differentiation protocols have be
Externí odkaz:
https://doaj.org/article/ee5163821687401ea645d2cea18c3874
Autor:
Zied Landoulsi, Sinthuja Pachchek, Dheeraj Reddy Bobbili, Lukas Pavelka, Patrick May, Rejko Krüger, the NCER-PD Consortium
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
ObjectivesTo explore the genetic architecture of PD in the Luxembourg Parkinson’s Study including cohorts of healthy people and patients with Parkinson’s disease (PD) and atypical parkinsonism (AP).Methods809 healthy controls, 680 PD and 103 AP w
Externí odkaz:
https://doaj.org/article/bba5dceb7aa64e058d0cb7efbed188ad
Autor:
Sinthuja Pachchek, Zied Landoulsi, Lukas Pavelka, Claudia Schulte, Elena Buena-Atienza, Caspar Gross, Ann-Kathrin Hauser, Dheeraj Reddy Bobbili, Nicolas Casadei, Patrick May, Rejko Krüger, on behalf of the NCER-PD Consortium
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/7ccab39398664c0ebd41162387c282c1
Autor:
Zied Landoulsi, Sawssan Benromdhan, Mouna Ben Djebara, Mariem Damak, Hamza Dallali, Rym Kefi, Sonia Abdelhak, Amina Gargouri-Berrechid, Chokri Mhiri, Riadh Gouider
Publikováno v:
BMC Medical Genetics, Vol 18, Iss 1, Pp 1-6 (2017)
Abstract Background In North African populations, G2019S mutation in LRRK2 gene, encoding for the leucine-rich repeat kinase 2, is the most prevalent mutation linked to familial and sporadic Parkinson’s disease (PD). Early detection of G2019S by fa
Externí odkaz:
https://doaj.org/article/7cee80f17c07414099568c49ea6f490c
Autor:
Giuseppe Arena, Zied Landoulsi, Dajana Grossmann, Armelle Vitali, Sylvie Delcambre, Alexandre Baron, Paul Antony, Ibrahim Boussaad, Dheeraj Reddy Bobbili, Ashwin Ashok Kumar Sreelatha, Lukas Pavelka, Christine Klein, Philip Seibler, Enrico Glaab, Manu Sharma, Rejko Krüger, Patrick May, Anne Grünewald
BackgroundParkinson’s disease (PD) is the fastest growing neurodegenerative disorder, with affected individuals expected to double during the next 20 years. This raises the urgent need to better understand the genetic architecture and downstream ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b8610eaf6683d16253af4317112d360
https://doi.org/10.1101/2023.05.12.23289877
https://doi.org/10.1101/2023.05.12.23289877
Autor:
Sinthuja Pachchek Peiris, Zied Landoulsi, Lukas Pavelka, Claudia Schulte, Elena Buena-Atienza, Caspar Gross, Ann-Kathrin Hauser, Dheeraj Reddy Bobbili, Nicolas Casadei, Patrick May, Rejko Krüger
Heterozygous variants in the glucocerebrosidase GBAgene are an increasingly recognized risk factor for Parkinson’s disease (PD). Due to the pseudogene GBAP1 that shares 96% sequence homology with the GBAcoding region, accurate variant calling by ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dabf30cb4a345cb32cdef6ed54170dea
https://doi.org/10.1101/2023.03.29.23287880
https://doi.org/10.1101/2023.03.29.23287880
Autor:
Semra Smajić, Cesar A. Prada-Medina, Zied Landoulsi, Jenny Ghelfi, Sylvie Delcambre, Carola Dietrich, Javier Jarazo, Jana Henck, Saranya Balachandran, Sinthuja Pachchek, Christopher M. Morris, Paul Antony, Bernd Timmermann, Sascha Sauer, Sandro L. Pereira, Jens C. Schwamborn, Patrick May, Anne Grünewald, Malte Spielmann
Publikováno v:
Brain
Idiopathic Parkinson’s disease is characterized by a progressive loss of dopaminergic neurons, but the exact disease aetiology remains largely unknown. To date, Parkinson’s disease research has mainly focused on nigral dopaminergic neurons, altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5537b72e848ef074330eb33e0d01f4
https://hdl.handle.net/21.11116/0000-000A-F076-221.11116/0000-0009-BFDC-9
https://hdl.handle.net/21.11116/0000-000A-F076-221.11116/0000-0009-BFDC-9
Autor:
Daniel Weiss, Zied Landoulsi, Patrick May, Manu Sharma, Michael Schüpbach, Hana You, Jean Christophe Corvol, Steffen Paschen, Ann-Kristin Helmers, Michael Barbe, Gereon Fink, Andrea A. Kühn, Christine Brefel Courbon, Lars Wojtecki, Philippe Damier, Valerie Fraix, Jean-Luc Houeto, Jean Regis, Friederike Sixel-Döring, Marcus O. Pinsker, Stephane Thobois, Alireza Gharabaghi, Valerie Stoker, Lars Timmermann, Alfons Schnitzler, Paul Krack, Marie Vidailhet, Günther Deuschl, Rejko Krüger
PURPOSE The decision for subthalamic deep brain stimulation (STN-DBS) in Parkinson's disease (PD) relies on clinical predictors. Whether genetic variables could predict favourable or unfavourable decisions is under investigation. OBJECTIVE First, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73dbb4a445fa91b1999002fa76c6f51d