Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Ziblat A"'
Autor:
Andrea Ziblat, Brendan L. Horton, Emily F. Higgs, Ken Hatogai, Anna Martinez, Jason W. Shapiro, Danny E.C. Kim, YuanYuan Zha, Randy F. Sweis, Thomas F. Gajewski
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114141- (2024)
Summary: The cellular source of positive signals that reinvigorate T cells within the tumor microenvironment (TME) for the therapeutic efficacy of programmed death-1 (PD-1)/programmed death-ligand 1 (PD-L1) blockade has not been clearly defined. We n
Externí odkaz:
https://doaj.org/article/478fd475a2364a4cb4cfc24d76e04912
Autor:
Ziblat, Andrea, Horton, Brendan L., Higgs, Emily F., Hatogai, Ken, Martinez, Anna, Shapiro, Jason W., Kim, Danny E.C., Zha, YuanYuan, Sweis, Randy F., Gajewski, Thomas F.
Publikováno v:
In Cell Reports 28 May 2024 43(5)
Autor:
Colin McGaw, Anthony J. Garrity, Gabrielle Z. Munoz, Jeffrey R. Haswell, Sejuti Sengupta, Elise Keston-Smith, Pratyusha Hunnewell, Alexa Ornstein, Mishti Bose, Quinton Wessells, Noah Jakimo, Paul Yan, Huaibin Zhang, Lauren E. Alfonse, Roy Ziblat, Jason M. Carte, Wei-Cheng Lu, Derek Cerchione, Brendan Hilbert, Shanmugapriya Sothiselvam, Winston X. Yan, David R. Cheng, David A. Scott, Tia DiTommaso, Shaorong Chong
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Cas12i is a genome editing platform with compact size that fits in AAV vector with short 43-mer gRNA, absence of tracrRNA, ability to process pre-crRNA, and high specificity. Here the authors present an unbiased mutational scanning approach to engine
Externí odkaz:
https://doaj.org/article/b34236ad23cc4e1cb4a7c8a576cc399b
Autor:
Montessori, Andrea, Lauricella, Marco, La Rocca, Michele, Succi, Sauro, Stolovicki, Elad, Ziblat, Roy, Weitz, David
We present a regularized version of the color gradient lattice Boltzmann (LB) scheme for the simulation of droplet formation in microfluidic devices of experimental relevance. The regularized version is shown to provide computationally efficient acce
Externí odkaz:
http://arxiv.org/abs/1711.02003
Autor:
Florencia Secchiari, Sol Yanel Nuñez, Jessica Mariel Sierra, Andrea Ziblat, María Victoria Regge, Ximena Lucía Raffo Iraolagoitia, Agustín Rovegno, Carlos Ameri, Fernando Pablo Secin, Nicolás Richards, Hernando Ríos Pita, Gonzalo Vitagliano, Luis Rico, Mauro Mieggi, Florencia Frascheri, Nicolás Bonanno, Leandro Blas, Aldana Trotta, Adrián David Friedrich, Mercedes Beatriz Fuertes, Carolina Inés Domaica, Norberto Walter Zwirner
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
NKG2D is a major natural killer (NK) cell-activating receptor that recognizes eight ligands (NKG2DLs), including MICA, and whose engagement triggers NK cell effector functions. As NKG2DLs are upregulated on tumor cells but tumors can subvert the NKG2
Externí odkaz:
https://doaj.org/article/1adb248fdaf140c9b28258767763461f
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/5cb7497e72c74b24a7a92a9984b2bef1
Autor:
Jessica M. Sierra, Florencia Secchiari, Sol Y. Nuñez, Ximena L. Raffo Iraolagoitia, Andrea Ziblat, Adrián D. Friedrich, María V. Regge, M. Cecilia Santilli, Nicolás I. Torres, Mariana Gantov, Aldana Trotta, Carlos Ameri, Gonzalo Vitagliano, Hernando Ríos Pita, Luis Rico, Agustín Rovegno, Nicolás Richards, Carolina I. Domaica, Norberto W. Zwirner, Mercedes B. Fuertes
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural Killer (NK) cells play a key role in cancer immunosurveillance. However, NK cells from cancer patients display an altered phenotype and impaired effector functions. In addition, evidence of a regulatory role for NK cells is emerging in divers
Externí odkaz:
https://doaj.org/article/3d8fa6bbe2054f3f9321c991e500c96a
Autor:
Andrea Ziblat, Ximena Lucía Raffo Iraolagoitia, Sol Yanel Nuñez, Nicolás Ignacio Torres, Florencia Secchiari, Jessica Mariel Sierra, Raúl Germán Spallanzani, Agustín Rovegno, Fernando Pablo Secin, Mercedes Beatriz Fuertes, Carolina Inés Domaica, Norberto Walter Zwirner
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Although natural killer (NK) cells infiltrate clear cell renal cell carcinomas (ccRCC), the most frequent malignancy of the kidney, tumor progression suggests that they become dysfunctional. As ccRCC-driven subversion of NK cell effector functions is
Externí odkaz:
https://doaj.org/article/7fcc502be5bf4a60b9407ff51b56cfca
Autor:
Montessori, Andrea, Lauricella, Marco, La Rocca, Michele, Succi, Sauro, Stolovicki, Elad, Ziblat, Roy, Weitz, David
Publikováno v:
In Computers and Fluids 15 May 2018 167:33-39
Autor:
Kenneth W Hance, Nicolas Torres, María Victoria Regge, Florencia Secchiari, Adrián David Friedrich, Raúl Germán Spallanzani, Ximena Lucía Raffo Iraolagoitia, Sol Yanel Núñez, Jessica Mariel Sierra, Andrea Ziblat, María Cecilia Santilli, Nicolás Gilio, Evangelina Almada, Constanza Lauche, Romina Pardo, Carolina Inés Domaica, Mercedes Beatriz Fuertes, Kevin Patrick Madauss, Israel S Gloger, Vanesa Zylberman, Fernando Alberto Goldbaum, Norberto Walter Zwirner
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Natural killer and cytotoxic CD8+ T cells are major players during antitumor immunity. They express NKG2D, an activating receptor that promotes tumor elimination through recognition of the MHC class I chain-related proteins A and B (MICA a
Externí odkaz:
https://doaj.org/article/60794d6d6f5348769085d3ffeeb174f9