Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Zibin GAO"'
Autor:
Jie Chen, Yumei Wang, Jia Deng, Rui Qing, Yaxi Yang, Xiaoliang Chen, Zibin Gao, Bochu Wang, Shilei Hao
Publikováno v:
Aggregate, Vol 5, Iss 2, Pp n/a-n/a (2024)
Abstract Recombinant keratins possess strong hemostatic and wound healing properties but suffer from poor water solubility that restricts their bioactivities in biomedical applications. Herein, we report the rational design and synthesis of water‐s
Externí odkaz:
https://doaj.org/article/20cb581b3a204af8b7aedf5643772235
Autor:
Yuanyuan Li, Xiaokun Cheng, Xinying Liu, Le Wang, Jing Ha, Zibin Gao, Xiaoliang He, Zhuo Wu, Aibing Chen, Linda L. Jewell, Yongjun Sun
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Excessive activation of N-methyl-d-aspartic acid (NMDA) receptors after cerebral ischemia is a key cause of ischemic injury. For a long time, it was generally accepted that calcium influx is a necessary condition for ischemic injury mediated by NMDA
Externí odkaz:
https://doaj.org/article/34ff8178d7044e439111b8a858d13745
Publikováno v:
Journal of Hebei University of Science and Technology, Vol 38, Iss 3, Pp 249-254 (2017)
In order to establish a NP-HPLC method for the determination of enantiomer in vildagliptin intermediate, the determination is carried out on the column of ChiralpakAD-H(250 mm×4.6 mm, 5 μm), with the mobile phase of n-hexane, ethanol and methanol
Externí odkaz:
https://doaj.org/article/9dc2c9aab3004b1fb10ed7450ccc1556
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Extracellular glutamate accumulation following cerebral ischemia leads to overactivation of glutamate receptors, thereby resulting in intracellular Ca2+ overload and excitotoxic neuronal injury. Multiple attempts have been made to counteract such eff
Externí odkaz:
https://doaj.org/article/7bff4441996245ffb0219a7c0d3f21c1
Autor:
Ning Shen, Jie Hu, Linan Zhang, Li Zhang, Yongjun Sun, Yinghua Xie, Shaomei Wu, Lei Liu, Zibin Gao
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 2, Iss 6, Pp 610-614 (2012)
The aim of this research was to evaluate doxorubicin (DOX)-loaded zein in situ gels, a new drug delivery system in which a liquid state drug can be transformed into semi-solid after intratumoral injection. In vitro release of DOX-loaded zein was inve
Externí odkaz:
https://doaj.org/article/0c49bb62e8ae419689c387f36284e66b
Publikováno v:
Journal of Hebei University of Science and Technology, Vol 36, Iss 1, Pp 30-35
To prepare aceclofenac pellets by centrifugal granulation. Using 90~100 g of starch pellets as the core pellets,100 g of aceclofenac mixed with 50 g of microcrystalline cellulose(MCC) and 4 g talc, methyl cellulose (HPMC) as binder,the aceclofenac pe
Externí odkaz:
https://doaj.org/article/4847620c50304cc1a3065a453316aba5
Autor:
Liling Chen, Run Meng, Rui Qing, Wenfeng Li, Ziwei Wang, Yao Hou, Jia Deng, Wei Pu, Zibin Gao, Bochu Wang, Shilei Hao
Publikováno v:
Nano letters. 22(22)
Although keratins are robust in nature, hydrogels producing their extracts exhibit poor mechanical properties due to the complicated composition and ineffective self-assembly. Here we report a bioinspired strategy to fabricate robust keratin hydrogel
Autor:
Ye Tian, Shuo Li, Peiyao Yang, Xiaolu Su, Jialu Liu, Xuening Lv, Kuan Dong, Ting Yang, Meibo Duan, Guangda Hu, Hao Yue, Yanping Sun, Yongjun Sun, Huimin Zhang, Zhidian Du, Zhenyu Miao, Minghui Tong, Yunlei Hou, Zibin Gao, Yanfang Zhao
Publikováno v:
Bioorganicmedicinal chemistry letters. 70
The pharmacological inhibition of soluble epoxide hydrolase (sEH) was shown to reduce inflammation and pain. Herein, we described a series of newly synthesized sEH inhibitors with the trident-shaped skeleton. Intensive structural modifications led to
Autor:
Ye Tian, Shuo Li, Kuan Dong, Xiaolu Su, Siyu Fu, Xuening Lv, Meibo Duan, Ting Yang, Yu Han, Guangda Hu, Jialu Liu, Yanping Sun, Hao Yue, Yongjun Sun, Huimin Zhang, Zhidian Du, Zhenyu Miao, Minghui Tong, Yajing Liu, Mingze Qin, Ping Gong, Yunlei Hou, Zibin Gao, Yanfang Zhao
Publikováno v:
Bioorganic chemistry. 127
The elevation of epoxy-fatty acids through inhibition of soluble epoxide hydrolase (sEH) is efficient for the treatment of inflammatory and pain-related diseases. Herein, we reported the discovery of a series of benzamide derivatives containing urea
Publikováno v:
Biointerphases. 17(2)
The lipid-coated mesoporous silica nanoparticles (LMSNs) that can synergistically harness the advantages and mitigate the disadvantages of the liposomes and MSNs are considered potential drug carriers. So far, several methods have been developed to p