Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Zian Xue"'
Autor:
Si-Yu Cen, Fang Lin, Xuan Li, Yanglin Hu, Jin-Pin Liu, Zian Xue, Yun Gao, Yi-Ping Sun, Sanyong Zhu, Yongjun Dang, Yahui Zhao, Hai-Xin Yuan
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Ferroptosis is a specific form of cell death characterized by excessive accumulation of cellular lipid peroxides. Ferroptosis is closely associated with various diseases, inhibition of which may help alleviate multi-organ injury caused by is
Externí odkaz:
https://doaj.org/article/8bb577e91b78432884b962ca9377ec37
Autor:
Huiti Li, Yali Liu, Zian Xue, Li Zhang, Xiaoxue Ruan, Jintong Yang, Zhongjiao Fan, Hongfang Zhao, Yu Cao, Guoqiang Chen, Ying Xu, Lu Zhou
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract Hypoxia inducible factor‐1α (HIF‐1α) plays a critical role in cellular adaptation to hypoxia and it is a potential therapeutic target for anti‐cancer drugs. Applying high‐throughput screening, here it is found that HI‐101, a smal
Externí odkaz:
https://doaj.org/article/d424d97313b04e23aace14a1d0dad293
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1864-1869
Autor:
Jin-Pin Liu, Si-Yu Cen, Zian Xue, Tian-Xiang Wang, Yun Gao, Jia Zheng, Cheng Zhang, Junchi Hu, Shenyou Nie, Yue Xiong, Kun-Liang Guan, Hai-Xin Yuan
Publikováno v:
ACS chemical biology. 17(12)
Ferroptosis is a nonapoptotic form of cell death characterized by iron-dependent lipid peroxidation and has been implicated in multiple pathological conditions. Glutathione peroxidase 4 (GPX4) plays an essential role in inhibiting ferroptosis by elim
Publikováno v:
ACS medicinal chemistry letters. 13(12)
Hypoxia-inducible factor, also known as HIF, is a transcriptional factor universally found in mammalian cells. HIF-1 is one of the HIF-families and acts as a heterodimer consisting of α and β subunits. It is found to play significant roles in patho