Prostate cancer metastasis: roles of recruitment and reprogramming, cell signal network and three-dimensional growth characteristics

Autor: Ziaee, Shabnam, Chu, Gina Chia-Yi, Huang, Jen-Ming, Sieh, Shirly, Chung, Leland W. K.

Publikováno v: Translational Andrology and Urology

Prostate cancer (PCa) metastasizes to bone and soft tissues, greatly decreasing quality of life, causing bone pain, skeletal complications, and mortality in PCa patients. While new treatment strategies are being developed, the molecular and cellular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ac817fb706cde19593e2293fe9f3f2d8
http://europepmc.org/articles/PMC4708593

Effective treatment of HER2-amplified breast cancer by targeting HER3 and β1 integrin

Autor: Campbell, Marcia R, Zhang, Hui, Ziaee, Shabnam, Ruiz-Saenz, Ana, Gulizia, Nathaniel, Oeffinger, Julie, Amin, Dhara N, Ahuja, Deepika, Moasser, Mark M, Park, Catherine C

Publikováno v: Campbell, Marcia R; Zhang, Hui; Ziaee, Shabnam; Ruiz-Saenz, Ana; Gulizia, Nathaniel; Oeffinger, Julie; et al.(2016). Effective treatment of HER2-amplified breast cancer by targeting HER3 and β1 integrin. Breast Cancer Research and Treatment, 155(3), 431-440. doi: 10.1007/s10549-016-3698-y. UC Office of the President: California Breast Cancer Research Program. Retrieved from: http://www.escholarship.org/uc/item/2rb4j2pd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::d73b2f956a47d8ecc74ee24b3dc29aa1
http://www.escholarship.org/uc/item/2rb4j2pd

Sabutoclax, a Mcl-1 Antagonist, Inhibits Tumorigenesis in Transgenic Mouse and Human Xenograft Models of Prostate Cancer12

Autor: Jackson, Roger S, Placzek, William, Fernandez, Ana, Ziaee, Shabnam, Chu, Chia-Yi, Wei, Jun, Stebbins, John, Kitada, Shinichi, Fritz, Gloria, Reed, John C, Chung, Leland W, Pellecchia, Maurizio, Bhowmick, Neil A

Resistance to available therapeutic agents has been a common problem thwarting progress in treatment of castrate-resistant and metastatic prostate cancer (PCa). Overexpression of the Bcl-2 family members, including Mcl-1, in PCa cells is known to inh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f184cb56ab5237edaa00fa571104516d
https://europepmc.org/articles/PMC3421961/

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