Highlighting the Major Role of Cyclin C in Cyclin-Dependent Kinase 8 Activity through Molecular Dynamics Simulations.

Autor: Ziada, Sonia¹ (AUTHOR) pascal.bonnet@univ-orleans.fr, Diharce, Julien² (AUTHOR) julien.diharce@u-paris.fr, Serillon, Dylan¹ (AUTHOR), Bonnet, Pascal¹ (AUTHOR), Aci-Sèche, Samia¹ (AUTHOR) samia.aci-seche@univ-orleans.fr

Publikováno v: International Journal of Molecular Sciences. May2024, Vol. 25 Issue 10, p5411. 22p.

Prédiction des constantes cinétiques de complexes protéine-ligand

Autor: Ziada, Sonia

Publikováno v: Chimie organique. Université d'Orléans, 2019. Français. ⟨NNT : 2019ORLE3175⟩

Over the past decade, there is an increasing interest for pharmaceutical companies in measuring and understanding drugs’ binding kinetics, in order to limit the most possible failure causes. Indeed, numerous studies demonstrate that preclinical eva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3515::e7e7b018bdfca5162c1599c012209414
https://theses.hal.science/tel-03853237/document

Enhanced molecular dynamics methods applied to drug design projects

Autor: Ziada, Sonia, Braka, Abdennour, Diharce, Julien, Aci-Seche, Samia, Bonnet, Pascal

Publikováno v: Methods in Molecular Biology
Methods in Molecular Biology, Humana Press/Springer Imprint, 2018, 1762, pp.403-426. ⟨10.1007/978-1-4939-7756-7_20⟩
Methods in Molecular Biology, 2018, 1762, pp.403-426. ⟨10.1007/978-1-4939-7756-7_20⟩

International audience; Nobel Laureate Richard P. Feynman stated: "[...] everything that living things do can be understood in terms of jiggling and wiggling of atoms [...]." The importance of computer simulations of macromolecules, which use classic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::38f5390eca01092cea170921b51653ea
https://hal.archives-ouvertes.fr/hal-01966502

Molecular Simulation Elaborating the Mechanism of 1β-Hydroxy Alantolactone Inhibiting Ubiquitin-Conjugating Enzyme UbcH5s.

Autor: Xu, Youdong¹, Meng, Xianli¹ xian_li_meng@163.com

Publikováno v: Scientific Reports. 1/10/2020, Vol. 10 Issue 1, p1-13. 13p.