Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Ziad Khatib"'
Autor:
Calixto-Hope G. Lucas, Rohit Gupta, Pamela Doo, Julieann C. Lee, Cathryn R. Cadwell, Biswarathan Ramani, Jeffrey W. Hofmann, Emily A. Sloan, Bette K. Kleinschmidt-DeMasters, Han S. Lee, Matthew D. Wood, Marjorie Grafe, Donald Born, Hannes Vogel, Shahriar Salamat, Diane Puccetti, David Scharnhorst, David Samuel, Tabitha Cooney, Elaine Cham, Lee-way Jin, Ziad Khatib, Ossama Maher, Gabriel Chamyan, Carole Brathwaite, Serguei Bannykh, Sabine Mueller, Cassie N. Kline, Anu Banerjee, Alyssa Reddy, Jennie W. Taylor, Jennifer L. Clarke, Nancy Ann Oberheim Bush, Nicholas Butowski, Nalin Gupta, Kurtis I. Auguste, Peter P. Sun, Jarod L. Roland, Corey Raffel, Manish K. Aghi, Philip Theodosopoulos, Edward Chang, Shawn Hervey-Jumper, Joanna J. Phillips, Melike Pekmezci, Andrew W. Bollen, Tarik Tihan, Susan Chang, Mitchel S. Berger, Arie Perry, David A. Solomon
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract The FGFR1 gene encoding fibroblast growth factor receptor 1 has emerged as a frequently altered oncogene in the pathogenesis of multiple low-grade neuroepithelial tumor (LGNET) subtypes including pilocytic astrocytoma, dysembryoplastic neuro
Externí odkaz:
https://doaj.org/article/3a46ceae1a2346d09a785ac62bd3c17d
Autor:
Kirby Quinn, Gareth P. Gilna, Gabriel Chamyan, Yamilet Tirado, Adriana Carrillo Iregui, Ziad Khatib, Claudia Fernandez-Castro, Clara Reyes, Ann C. Brady, Anthony R. Hogan, Chad M. Thorson
Publikováno v:
Journal of Pediatric Surgery Case Reports, Vol 73, Iss , Pp 102004- (2021)
Congenital cervical germ cell tumors are a rare location for extragonadal germ cell tumors that may lead to acute airway obstruction. We present the unique case and successful resection of an immature cervical teratoma. Urgent Ex Utero Intrapartum Tr
Externí odkaz:
https://doaj.org/article/b9c8e3a95e364aeb9bc0915b9620ea75
Effect of Postoperative Radiation Therapy Timing on Survival in Pediatric and Young Adult Ependymoma
Autor:
Sunny Shah, MS, Kevin Gates, MS, Chase Mallory, BHS, Muni Rubens, PhD, MPH, Ossama M. Maher, MD, Toba N. Niazi, MD, Ziad Khatib, MD, Rupesh Kotecha, MD, Minesh P. Mehta, MD, Matthew D. Hall, MD, MBA
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 4, Pp 100691- (2021)
Purpose: Postoperative radiation therapy (RT) is commonly used for World Health Organization grade II-III intracranial ependymoma. Clinicians generally aim to begin RT ≤5 weeks after surgery, but postoperative recovery and need for second look surg
Externí odkaz:
https://doaj.org/article/8e26e6b80dc74ca8bbed156cdcfba42f
Autor:
Melike Pekmezci, Javier E. Villanueva-Meyer, Benjamin Goode, Jessica Van Ziffle, Courtney Onodera, James P. Grenert, Boris C. Bastian, Gabriel Chamyan, Ossama M. Maher, Ziad Khatib, Bette K. Kleinschmidt-DeMasters, David Samuel, Sabine Mueller, Anuradha Banerjee, Jennifer L. Clarke, Tabitha Cooney, Joseph Torkildson, Nalin Gupta, Philip Theodosopoulos, Edward F. Chang, Mitchel Berger, Andrew W. Bollen, Arie Perry, Tarik Tihan, David A. Solomon
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-11 (2018)
Abstract Ganglioglioma is the most common epilepsy-associated neoplasm that accounts for approximately 2% of all primary brain tumors. While a subset of gangliogliomas are known to harbor the activating p.V600E mutation in the BRAF oncogene, the gene
Externí odkaz:
https://doaj.org/article/718ab3844687460888c12121ec691e7a
Autor:
Jacklyn D. Smith, Gabriel Mandel, Toba Niazi, Julie A. Bradley, Daniel J. Indelicato, Ziad Khatib
Publikováno v:
Journal of child neurology. 37(7)
Radiation treatment is widely used to address unresectable intracranial tumors. Owing to the nature of therapy, healthy tissue and diseased regions will be affected. New insights have shown that not only does this impact brain parenchyma but it cause
Autor:
Arlet Maria Acanda de la Rocha, Maggie Fader, Ebony R. Coats, Joseph Dunn, Leat Perez, Carolina Velasquez, Jeanette Galano, Cima Saghira, Ileana Sotto, Yana Vorontsova, Ziad Khatib, Haneen Abdella, Cristina M. Andrade-Feraud, Alexa Jacome, Victoria Reis, Lilliam Rimblas, Nicole Tomas, Paula S. Espinal, Noah Berlow, Tomás R. Guilarte, Jennifer McCafferty-Fernandez, Daria Salyakina, Diana J. Azzam
Publikováno v:
Cancer Research. 83:LB358-LB358
Personalized medicine often serves as the first salvage therapy strategy when standard oncology treatments fail. However, most precision oncology approaches rely on molecular profiling which, unfortunately, provides therapeutic options for less than
Autor:
Ziad Khatib, Frederic A. Vallejo, Winston M. Walters, Sumedh S. Shah, Jeffrey S. Prince, Ricardo J. Komotar, Regina M. Graham, Steven Vanni, Nicolas de Cordoba
Publikováno v:
Journal of Neuro-Oncology. 147:317-326
Glioblastoma (GBM) remains one of the most lethal primary brain tumors in children and adults. Targeting tumor metabolism has emerged as a promising-targeted therapeutic strategy for GBM and characteristically resistant GBM stem-like cells (GSCs). Ge
Autor:
Sharon L Gardner, Rohinton S Tarapore, Jeffrey Allen, Susan L McGovern, Wafik Zaky, Yazmin Odia, Doured Daghistani, Zuanel Diaz, Matthew D Hall, Ziad Khatib, Carl Koschmann, Evan Cantor, Ryo Kurokawa, Tobey J MacDonald, Dolly Aguilera, Nicholas A Vitanza, Sabine Mueller, Cassie Kline, Guangrong Lu, Joshua E Allen, Soumen Khatua
Publikováno v:
Neuro-Oncology Advances. 4
Background ONC201, a dopamine receptor D2 (DRD2) antagonist and caseinolytic protease P (ClpP) agonist, has induced durable tumor regressions in adults with recurrent H3 K27M-mutant glioma. We report results from the first phase I pediatric clinical
Autor:
Nathan Robison, Jasmine Pauly, Jemily Malvar, Sharon Gardner, Jeffrey Allen, Ashley Margol, Tobey MacDonald, Anne Bendel, Lindsay Kilburn, Andrew Cluster, Daniel Bowers, Kathleen Dorris, Nicole Ullrich, Rebecca Loret De Mola, Elizabeth Alva, Sarah Leary, Patricia Baxter, Ziad Khatib, Kenneth Cohen, Tom Belle Davidson, Ashley Plant, Pratiti Bandopadhayay, Sylwia Stopka, Nathalie Agar, Karen Wright, Marvin Nelson, Yueh-Yun Chi, Mark Kieran
Publikováno v:
Neuro-Oncology. 24:i191-i192
BACKGROUND RAS/RAF/MEK/ERK pathway activation is the primary driver for most pediatric low-grade gliomas (pLGG). MEK162 (binimetinib) is an orally bioavailable MEK1/2 inhibitor with superior brain penetration in a preclinical model. The primary objec
Autor:
Cristina M Andrade-Feraud, Arlet M. Acanda de la Rocha, Ileana Sotto, Haneen Abdella, Maggie Fader, Daria Salyakina, Michelin Janvier, Tomás R. Guilarte, Vanessa Berrios, Mathew Bittle, Ziad Khatib, Ebony R Coats, Diana J. Azzam, Jennifer McCafferty-Fernandez, Paula S Espinal, Rojesh Shakya, Cima Saghira
Publikováno v:
JCO Precision Oncology