Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Zi-ying Zhou"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117260- (2024)
The five-year survival rate for patients with hepatocellular carcinoma (HCC) is only 20 %, highlighting the urgent need to identify new therapeutic targets and develop potential therapeutic options to improve patient prognosis. One promising approach
Externí odkaz:
https://doaj.org/article/381554c557514d59a2f0fd0dfad5488a
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 116018- (2024)
Hepatocellular carcinoma (HCC) is one of the most fatal solid malignancies worldwide. Evidence suggests that thrombin stimulates tumor progression via fibrin formation and platelet activation. Meanwhile, we also found a correlation between thrombin a
Externí odkaz:
https://doaj.org/article/96da8da8d80f46c0906314eb9d909f31
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Ovarian cancer (OC) is a gynecological tumor with possibly the worst prognosis, its 5-year survival rate being only 47.4%. The first line of therapy prescribed is chemotherapy consisting of platinum and paclitaxel. The primary reason for treatment fa
Externí odkaz:
https://doaj.org/article/792c8df86d5645c699087a8a9b115cb2
Autor:
Xiahenazi Aiyasiding, Hai-Han Liao, Hong Feng, Nan Zhang, Zheng Lin, Wen Ding, Han Yan, Zi-Ying Zhou, Qi-Zhu Tang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Liquiritin (LQ) is one of the main flavonoids extracted from the roots of Glycyrrhiza spp., which are widely used in traditional Chinese medicine. Studies in both cellular and animal disease models have shown that LQ attenuates or prevent
Externí odkaz:
https://doaj.org/article/30857b101f234265a4ba056587f3eff4
Autor:
Wen-jing Li, Hai-han Liao, Hong Feng, Zi-ying Zhou, Shan-qi Mou, Nan Zhang, Hai-ming Wu, Hao Xia, Qi-zhu Tang
Publikováno v:
Journal of Pharmacological Sciences, Vol 143, Iss 3, Pp 199-208 (2020)
The optimum strategy for heart failure (HF) treatment has yet to be elucidated. This study intended to test the benefit of a combination of valsartan (VAL) and perifosine (PER), a specific AKT inhibitor, in protecting against pressure overload induce
Externí odkaz:
https://doaj.org/article/28f324dc5dba4c818b0ad8e56258b1b0
Autor:
Nan Zhang, Hai-Han Liao, Hong Feng, Shan-Qi Mou, Wen-Jing Li, Xiahenazi Aiyasiding, Zheng Lin, Wen Ding, Zi-Ying Zhou, Han Yan, Si Chen, Qi-Zhu Tang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Objectives: Sestrin2 (Sesn2) has been demonstrated to be a cysteine sulfinyl reductase and protects cells from multiple stress insults, including hypoxia, endoplasmic reticulum stress, and oxidative stress. However, the roles and mechanisms of Sesn2
Externí odkaz:
https://doaj.org/article/f50d65d73ef8430e9d5b093ff50588cb
Autor:
Jing-jing Yang, Nan Zhang, Zi-ying Zhou, Jian Ni, Hong Feng, Wen-jing Li, Shan-qi Mou, Hai-ming Wu, Wei Deng, Hai-han Liao, Qi-zhu Tang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
This study aimed to investigate the role and mechanisms of Receptor interacting protein kinase 2 (RIP2) in pressure overload-induced cardiac remodeling. Human failing or healthy donor hearts were collected for detecting RIP2 expression. RIP2 cardiomy
Externí odkaz:
https://doaj.org/article/b32f50068d084c98b257ec01a6191e2c
Autor:
Shan-Qi Mou, Zi-Ying Zhou, Hong Feng, Nan Zhang, Zheng Lin, Xiahenazi Aiyasiding, Wen-Jing Li, Wen Ding, Hai-Han Liao, Zhou-Yan Bian, Qi-Zhu Tang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Liquiritin (LIQ) is a traditional Chinese medicine that has been reported to regulate inflammation, oxidative stress and cell apoptosis. However, the beneficial effects of LIQ in lipopolysaccharides (LPS)-induced septic cardiomyopathy (SC
Externí odkaz:
https://doaj.org/article/5efc968362fc4781b12131305384243a
Autor:
Yu-Lin Chen, Ying-Hui Dai, An-Dong Wang, Zi-Ying Zhou, Miao Lei, Jiao Liu, Bin Lin, Ming-Yu Xia, Dong Wang
Publikováno v:
Molecules, Vol 25, Iss 19, p 4511 (2020)
Two new indole alkaloids, Bufotenidine B (2) and Bufocarboline A (6), along with seven known indole alkaloids (1, 3–5, and 7–9) and three organic acids (10–12), were isolated from the water extract of toad venom. The structures of the new alkal
Externí odkaz:
https://doaj.org/article/1f8dad4b357943bda6247a565e0bccb1
Autor:
Zi-ying Zhou, Lian-qi Sun, Xiao-yang Han, Yong-jian Wang, Zhuo-song Xie, Si-tu Xue, Zhuo-rong Li
Publikováno v:
Journal of Medicinal Chemistry. 66:1742-1760