Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Zi-Zong Ho"'
Autor:
Anthony Tanoto Tan, Fanping Meng, Jiehua Jin, Ji‐Yuan Zhang, Si‐Yu Wang, Lei Shi, Ming Shi, Yuanyuan Li, Yunbo Xie, Li‐Min Liu, Chun‐Bao Zhou, Alicia Chua, Zi Zong Ho, Junqing Luan, Jinfang Zhao, Jing Li, Lu‐En Wai, Sarene Koh, Tingting Wang, Antonio Bertoletti, Fu‐sheng Wang
Publikováno v:
Hepatology Communications, Vol 6, Iss 4, Pp 841-854 (2022)
The application of hepatitis B virus (HBV)–T‐cell receptor (TCR) T‐cell immunotherapy in patients with HBV‐related hepatocellular carcinoma (HBV‐HCC) has been apathetic, as the expression of HBV antigens by both normal HBV‐infected hepato
Externí odkaz:
https://doaj.org/article/ce80954e15004b0fb40702d77991ad40
Autor:
Xiang Zhao, Shvetha Sankaran, Jiawei Yap, Chien Tei Too, Zi Zong Ho, Garry Dolton, Mateusz Legut, Ee Chee Ren, Andrew K. Sewell, Antonio Bertoletti, Paul A. MacAry, Joanna Brzostek, Nicholas R. J. Gascoigne
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Coagonism, the ability of nonstimulatory antigens to promote T-cell activation, has been reported in mice. Here the authors show that coagonism also occurs in human CD8 T cells, in which a nonstimulatory HIV GAG peptide enhances a specific T-cell res
Externí odkaz:
https://doaj.org/article/e1513454279048d48870135ba8d4a18d
Autor:
Anthony Tanoto Tan, Fanping Meng, Jiehua Jin, Ji‐Yuan Zhang, Si‐Yu Wang, Lei Shi, Ming Shi, Yuanyuan Li, Yunbo Xie, Li‐Min Liu, Chun‐Bao Zhou, Alicia Chua, Zi Zong Ho, Junqing Luan, Jinfang Zhao, Jing Li, Lu‐En Wai, Sarene Koh, Tingting Wang, Antonio Bertoletti, Fu‐sheng Wang
Publikováno v:
Hepatology communications. 6(4)
The application of hepatitis B virus (HBV)-T-cell receptor (TCR) T-cell immunotherapy in patients with HBV-related hepatocellular carcinoma (HBV-HCC) has been apathetic, as the expression of HBV antigens by both normal HBV-infected hepatocytes and HC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee67d9100ad2dedbc371d2185932aba2
https://pubmed.ncbi.nlm.nih.gov/34935312
https://pubmed.ncbi.nlm.nih.gov/34935312
Autor:
Sarene Koh, Noriko Shimasaki, Rossarin Suwanarusk, Zi Zong Ho, Adeline Chia, Nasirah Banu, Shanshan Wu Howland, Alice Soh Meoy Ong, Adam J Gehring, Hans Stauss, Laurent Renia, Matti Sällberg, Dario Campana, Antonio Bertoletti
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Hepatocellular carcinoma (HCC) cells often have hepatitis B virus (HBV)-DNA integration and can be targeted by HBV-specific T cells. The use of viral vectors to introduce exogenous HBV-specific T-cell receptors (TCR) on T cells to redirect their spec
Externí odkaz:
https://doaj.org/article/e9fd7843759f49c69a0b5008cd80134b
Autor:
Antonio Bertoletti, Royce Fam, Andrea Pavesi, Wan Cheng Chow, Meiyin Lin, Lu-En Wai, Joey Aw, Zi Zong Ho, Anthony T. Tan, Damien Tan, Morteza Hafezi, Qi Zhang, Sarene Koh, Wenjie Chen, Thinesh Lee Krishnamoorthy, Adeline Chia, Alicia Chua
Publikováno v:
Hepatology (Baltimore, Md.)References. 74(1)
BACKGROUND AND AIMS HBV-specific T-cell receptor (HBV-TCR) engineered T cells have the potential for treating HCC relapses after liver transplantation, but their efficacy can be hampered by the concomitant immunosuppressive treatment required to prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283038543921992ce2c8bd689a2d8e6c
https://pubmed.ncbi.nlm.nih.gov/33249625
https://pubmed.ncbi.nlm.nih.gov/33249625
Autor:
Jianrong L Low, Anneta Naidoo, Gladys Yeo, Adam J Gehring, Zi Zong Ho, Yin Hoe Yau, Susana G Shochat, David M Kranz, Antonio Bertoletti, Gijsbert M Grotenbreg
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51397 (2012)
Class I Major Histocompatibility Complex (MHC) molecules evolved to sample degraded protein fragments from the interior of the cell, and to display them at the surface for immune surveillance by CD8(+) T cells. The ability of these lymphocytes to ide
Externí odkaz:
https://doaj.org/article/f2d75e68c2454673b68f16005f836244
Autor:
Adam J Gehring, Sarene Koh, Adeline Chia, Komathi Paramasivam, Valerie Suk Peng Chew, Zi Zong Ho, Kang Hoe Lee, Mala K Maini, Krishnakumar Madhavan, Seng Gee Lim, Antonio Bertoletti
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23330 (2011)
T cell functional plasticity helps tailor antiviral immunity during different phases of infections. We tested whether, during different phases of HBV infection, virus-specific T cells can acquire specific proinflammatory functions that could drive gr
Externí odkaz:
https://doaj.org/article/a57b8fd111ea4ebdbda10dda95b70013
Spatiotemporal Differences in Presentation of CD8 T Cell Epitopes during Hepatitis B Virus Infection
Autor:
Patrick T F Kennedy, Zi Zong Ho, Ninghan Yang, Jia Xin Chow, Yi Ni, Atefeh Khakpoor, Stephan Urban, Antonio Bertoletti, Anthony T. Tan, Reshmi Giri, Vincent Yi Sheng Oei, Antony K. Chen, Mala K. Maini
Publikováno v:
Journal of Virology
The inability of patients with chronic HBV infection to clear HBV is associated with defective HBV-specific CD8+ T cells. Hence, the majority of immunotherapy developments focus on HBV-specific T cell function restoration. However, knowledge of wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b3764152dfa641a8d2f540b62b44ac
https://doi.org/10.1128/jvi.01457-18
https://doi.org/10.1128/jvi.01457-18
Autor:
Paul A. MacAry, Keith G. Gould, Joanna Ai Ling Choo, Ee Chee Ren, Maryam Hamidinia, Nicholas R. J. Gascoigne, Zi Zong Ho, Antonio Bertoletti, Joanna Brzostek, Chien Tei Too, Xiang Zhao
Non-stimulatory self peptide MHC (pMHC) complexes do not induce T cell activation and effector functions, but can enhance T cell responses to agonist pMHC, through a process termed co-agonism. This protocol describes an experimental system to investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83717b9248868b8c186dcaa0e471d8d6
http://hdl.handle.net/10044/1/68800
http://hdl.handle.net/10044/1/68800
Autor:
Thinesh Lee Krishnamoorthy, Zi Zong Ho, Xinyuan Zhao, Wan Cheng Chow, Adeline Chia, Ninghan Yang, Hui Si Tan, Hiang Keat Tan, Diana Low, Qi Zhang, William Hwang, Ernesto Guccione, Alicia Chua, Vincent Yi Sheng Oei, Anthony T. Tan, Nina Le Bert, Rajneesh Kumar, Sarene Koh, Lu-En Wai, Farah Gillan Irani, Antonio Bertoletti
Publikováno v:
Gastroenterology. 156(6)
Background & Aims Hepatocellular carcinoma (HCC) is often associated with hepatitis B virus (HBV) infection. Cells of most HBV-related HCCs contain HBV-DNA fragments that do not encode entire HBV antigens. We investigated whether these integrated HBV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f430edadc039882fd96169f64af9f1
https://pubmed.ncbi.nlm.nih.gov/30711630
https://pubmed.ncbi.nlm.nih.gov/30711630