Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Zi-Tian Wu"'
Autor:
Zhuo-Qing Li, Li-Long Jiang, Dong-Sheng Zhao, Jing Zhou, Ling-Li Wang, Zi-Tian Wu, Xian Zheng, Zi-Qi Shi, Ping Li, Hui-Jun Li
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Dictamni Cortex (DC) has been reported to be associated with acute hepatitis in clinic and may lead to a selective sub-chronic hepatotoxicity in rats. Nevertheless, the potent toxic ingredient and the underlying mechanism remain unknown. Dictamnine (
Externí odkaz:
https://doaj.org/article/17e0ef926f5748f395b240aafa94efe1
Publikováno v:
Chinese Journal of Natural Medicines. 18:57-69
Diterpenoid lactones (DLs), a group of furan-containing compounds found in Dioscorea bulbifera L. (DB), have been reported to be associated with hepatotoxicity. Different hepatotoxicities of these DLs have been observed in vitro, but reasonable expla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2bbcecb8f0cc942aa05a20a0f4e1ff
https://doi.org/10.1016/s1875-5364(20)30005-4
https://doi.org/10.1016/s1875-5364(20)30005-4
Autor:
Hui-Jun Li, Zi-Tian Wu, Zhuo-Qing Li, Dong-Sheng Zhao, Ling-Li Wang, Li-Long Jiang, Wei Shi, Ping Li
Publikováno v:
Journal of Ethnopharmacology. 226:111-119
Ethnopharmacological relevance Dioscorea bulbifera rhizome (DBR), one type of herbal medicine, is extensively used in both Indian and Chinese system of traditional medicine. It has been effective in treating various diseases, such as sore throat, str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::027ea32332d34cce15249541793b4139
https://doi.org/10.1016/j.jep.2018.08.014
https://doi.org/10.1016/j.jep.2018.08.014
Autor:
Zi-Tian Wu, Hui-Jun Li, Wei Shi, Dong-Sheng Zhao, Ling-Li Wang, Ying-Jie Wei, Ping Li, Li-Long Jiang, Jie Ling
Publikováno v:
RSC Advances. 8:7765-7773
Diterpenoid lactones (DLs) have been reported to be the main hepatotoxic constituents in Dioscorea bulbifera tubers (DBT), a traditional Chinese medicinal herb. The acquisition of early information regarding its metabolism is critical for evaluating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7dabf7457846b74e165855e1534a1bf
https://doi.org/10.1039/c7ra12910f
https://doi.org/10.1039/c7ra12910f
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 142:201-209
Cyclopamine, an inhibitor of the Hedgehog (Hh) signaling pathway, has been paid much attention in treating a wide variety of tumors. However, isolation and purification of cyclopamine analogs from medicinal plants remain challengeable. We herein prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b921e0a79262542a746fe1681338e0
https://doi.org/10.1016/j.jpba.2017.04.049
https://doi.org/10.1016/j.jpba.2017.04.049
Autor:
Wei Shi, Yan Jiang, Zi-Tian Wu, Hui-Jun Li, Zhuo-Qing Li, Ping Li, Ling-Li Wang, Dong-Sheng Zhao, Li-Long Jiang
Publikováno v:
Chemical research in toxicology. 31(9)
Previous studies have shown that Dioscorea bulbifera rhizome (DBR) can induce hepatotoxicity in clinical practice. However, its underlying mechanisms remain largely unexplored. In the present study, we investigated the global effect of DBR exposure o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f173cee533925c17f2d6b87104e737e
https://pubmed.ncbi.nlm.nih.gov/30052031
https://pubmed.ncbi.nlm.nih.gov/30052031
Autor:
Dong-Sheng, Zhao, Zi-Tian, Wu, Zhuo-Qing, Li, Ling-Li, Wang, Li-Long, Jiang, Wei, Shi, Ping, Li, Hui-Jun, Li
Publikováno v:
Journal of ethnopharmacology. 226
Dioscorea bulbifera rhizome (DBR), one type of herbal medicine, is extensively used in both Indian and Chinese system of traditional medicine. It has been effective in treating various diseases, such as sore throat, struma, and tumors. However, more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9bf4dd6001e98d456f597bb31cd02c8
https://pubmed.ncbi.nlm.nih.gov/30114519
https://pubmed.ncbi.nlm.nih.gov/30114519
Autor:
Wei, Shi, Jie, Ling, Li-Long, Jiang, Dong-Sheng, Zhao, Ling-Li, Wang, Zi-Tian, Wu, Ping, Li, Ying-Jie, Wei, Hui-Jun, Li
Publikováno v:
RSC advances. 8(14)
Diterpenoid lactones (DLs) have been reported to be the main hepatotoxic constituents in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c3f521e37ab61f0f3f25348af904546
https://pubmed.ncbi.nlm.nih.gov/35539098
https://pubmed.ncbi.nlm.nih.gov/35539098
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1064
It is vital to monitor the holistic toxicokinetics of toxic Chinese herbal medicines (CHMs) for safety. Although an integrated strategy based on the area under the curve (AUC) has been proposed to characterize the pharmacokinetic/toxicokinetic proper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1eec2b63a9ad318b6c5822fc92c41c
https://pubmed.ncbi.nlm.nih.gov/28910661
https://pubmed.ncbi.nlm.nih.gov/28910661