Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Zi-Ming Cheng"'
Autor:
Qianjin Guo, Zi-Ming Cheng, Hector Gonzalez-Cantú, Matthew Rotondi, Gabriela Huelgas-Morales, Purushoth Ethiraj, Zhijun Qiu, Jonathan Lefkowitz, Wan Song, Bethany N. Landry, Hector Lopez, Cynthia M. Estrada-Zuniga, Shivi Goyal, Mohammad Aasif Khan, Timothy J. Walker, Exing Wang, Faqian Li, Yanli Ding, Lois M. Mulligan, Ricardo C.T. Aguiar, Patricia L.M. Dahia
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113070- (2023)
Summary: The TMEM127 gene encodes a transmembrane protein of poorly known function that is mutated in pheochromocytomas, neural crest-derived tumors of adrenomedullary cells. Here, we report that, at single-nucleus resolution, TMEM127-mutant tumors s
Externí odkaz:
https://doaj.org/article/74efd737d1554c5e84e35c4daa5fe892
Autor:
Subramanya Srikantan, Yilun Deng, Zi-Ming Cheng, Anqi Luo, Yuejuan Qin, Qing Gao, Glaiza-Mae Sande-Docor, Sifan Tao, Xingyu Zhang, Nathan Harper, Chris E. Shannon, Marcel Fourcaudot, Zhi Li, Balakuntalam S. Kasinath, Stephen Harrison, Sunil Ahuja, Robert L. Reddick, Lily Q. Dong, Muhammad Abdul-Ghani, Luke Norton, Ricardo C. T. Aguiar, Patricia L. M. Dahia
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
TMEM127 is a tumor suppressor protein, loss of which predisposes to catecholamine-secreting tumors. Here the authors show that TMEM127 expression is modulated by nutritional status and that it has a role in regulating organismal insulin sensitivity.
Externí odkaz:
https://doaj.org/article/759408e47c5a4d35885debb0d56f6eb3
Autor:
Zhi-chang, Fu, Zi-ming, Cheng, Fu-qiang, Wang, Yan, Dong, Xin-ping, Zhang, Ao-yu, Zhang, Hua-xu, Liang
Publikováno v:
In Optik October 2023 289
Autor:
Patricia L.M. Dahia, Ricardo C.T. Aguiar, Yidong Chen, Robert L. Reddick, Jan Bruder, Marta Barontini, Neil Aronin, Sarika Rao, I. Tolgay Ocal, Manju L. Prasad, Gustavo M. Silva, Shintaro Iwata, Qing Gao, Zi-Ming Cheng, Yuejuan Qin, Rodrigo A. Toledo
Supplementary Appendix: List of all supplementary data files; Supplemental Methods: Additional clinical details of Samples, and details of whole exome sequencing, targeted sequencing and in silico structure modeling not included in main article
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62fadc0665be6fa207fdff19736c5c9c
https://doi.org/10.1158/1078-0432.22457802.v1
https://doi.org/10.1158/1078-0432.22457802.v1
Autor:
Patricia L.M. Dahia, Ricardo C.T. Aguiar, Yidong Chen, Robert L. Reddick, Jan Bruder, Marta Barontini, Neil Aronin, Sarika Rao, I. Tolgay Ocal, Manju L. Prasad, Gustavo M. Silva, Shintaro Iwata, Qing Gao, Zi-Ming Cheng, Yuejuan Qin, Rodrigo A. Toledo
Purpose: Pheochromocytomas and paragangliomas (PPGL) are genetically heterogeneous tumors of neural crest origin, but the molecular basis of most PPGLs is unknown.Experimental Design: We performed exome or transcriptome sequencing of 43 samples from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c258e7c083018896e91674880a4ec87
https://doi.org/10.1158/1078-0432.c.6523701.v1
https://doi.org/10.1158/1078-0432.c.6523701.v1
Autor:
Patricia L.M. Dahia, Ricardo C.T. Aguiar, Yidong Chen, Robert L. Reddick, Jan Bruder, Marta Barontini, Neil Aronin, Sarika Rao, I. Tolgay Ocal, Manju L. Prasad, Gustavo M. Silva, Shintaro Iwata, Qing Gao, Zi-Ming Cheng, Yuejuan Qin, Rodrigo A. Toledo
Supplemental Figure 1: Alternative views of Figure 1 displaying mutations in our cohort; Supplemental Figure 2: Histone 3.3 G34W mutation in patient samples; Supplemental Figure 3: In silico analysis of histone 3.3 and G34W mutant; Supplemental Figur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9318cf4ace5911fb2633c48d842a6d
https://doi.org/10.1158/1078-0432.22457808
https://doi.org/10.1158/1078-0432.22457808
Autor:
Patricia L.M. Dahia, Ricardo C.T. Aguiar, Yidong Chen, Robert L. Reddick, Jan Bruder, Marta Barontini, Neil Aronin, Sarika Rao, I. Tolgay Ocal, Manju L. Prasad, Gustavo M. Silva, Shintaro Iwata, Qing Gao, Zi-Ming Cheng, Yuejuan Qin, Rodrigo A. Toledo
Table S1: Features of the 41 samples of the next-generation sequencing (NGS) cohort; Table S2: Mutations identified in known pheochromocytoma/paraganglioma-related genes in the NGS cohort; Table S3: Features of the validation cohort of 136 pheochromo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dab9b55fb4482a505f320c3c03a2880
https://doi.org/10.1158/1078-0432.22457805.v1
https://doi.org/10.1158/1078-0432.22457805.v1
Autor:
Daniel Katselnik, Yanli Ding, Camilo Jimenez, Michael A. Liss, Bernadette Biondi, Zi Ming Cheng, Tobias Else, Marta Barontini, Nelly Burnichon, Rory Clifton-Bligh, Gustavo Armaiz-Pena, Alfredo A. Santillan-Gomez, Andrea Alvarez-Eslava, Deepa Vincent, Oksana Hamidi, Mio Kitano, Trisha Dwight, Enrique Maldonado, Joel E. Michalek, Diana E. Benn, Emmanuel Esquivel, Gabriela Sanso, Anne Paule Gimenez-Roqueplo, Maureen Koops, Art S. Tischler, Patricia L. M. Dahia, Xhingyu Zhang, Lauren Fishbein, Natalie Poullard, Anusha Vaidyanathan, Qianqian Liu, Shahida K. Flores, Neil Aronin, Ron Lechan, Elizabeth Bowhay-Carnes, Sara Ahmadi, Jan M. Bruder, Sarimar Agosto Salgado
Publikováno v:
J Clin Endocrinol Metab
Purpose This work aimed to evaluate genotype-phenotype associations in individuals carrying germline variants of transmembrane protein 127 gene (TMEM127), a poorly known gene that confers susceptibility to pheochromocytoma (PHEO) and paraganglioma (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e54bfa76c78ec866835518d27cac3fb
https://doi.org/10.1210/clinem/dgaa741
https://doi.org/10.1210/clinem/dgaa741
Autor:
Cynthia Estrada-Zuniga, Zi-Ming Cheng, Qianjin Guo, Purushoth Ethiraj, Elaina Adderley, Neil Aronin, Yanli Ding, Xiaojing Wang, Ricardo C.T. Aguiar, Patricia L. M. Dahia
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dd2a15c56f4cdfc294d2aaef2696fe5
https://doi.org/10.2139/ssrn.4005584
https://doi.org/10.2139/ssrn.4005584
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