Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Zi-Fei Zhu"'
Publikováno v:
Chinese Chemical Letters. 26:759-762
Thirteen novel NO-releasing derivatives of betulinic acid (BA) bearing two types of NO-donors (nitrates and furoxans) were synthesized and evaluated for their antitumor activity. The results showed that furoxan-based derivatives exhibited higher anti
Publikováno v:
Chinese Journal of Natural Medicines. 8:436-440
Aim To synthesize oleanolic acid/ N -aryl- N' -hydroxyguanidine hybrids and evaluate their antitumor activity. Methods Substituted N -aryl- N' -hydroxyguanidines were conjugated with C3-OH of OA via succinyl, giving eight target compounds, whose cyto
Publikováno v:
Journal of Asian natural products research. 16(1)
Seventeen new derivatives of betulinic acid (BA) with potential anti-tumor activity have been synthesized. In order to improve the bioactivity of BA, we connected BA and nitric oxide donors together via different linkers. The results of the biologica