Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Zi Fei Pei"'
Autor:
Zheng Wu, Matthew Parry, Xiao-Yi Hou, Min-Hui Liu, Hui Wang, Rachel Cain, Zi-Fei Pei, Yu-Chen Chen, Zi-Yuan Guo, Sambangi Abhijeet, Gong Chen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
In vivo reprogramming of reactive glia using transfection of a single transcription factor has been described before by these authors and applied to models of neurodegeneration. Here the authors use this procedure in the R6/2 mouse model of Huntingto
Externí odkaz:
https://doaj.org/article/2387e888eee84d4b8badfe7bc66564ae
Autor:
Min Hui Liu, Matthew Parry, Xiao Yi Hou, Rachel Cain, Gong Chen, Hui Wang, Yuchen Chen, Sambangi Abhijeet, Zi Fei Pei, Zheng Wu, Zi Yuan Guo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications
Huntington’s disease (HD) is caused by Huntingtin (Htt) gene mutation resulting in the loss of striatal GABAergic neurons and motor functional deficits. We report here an in vivo cell conversion technology to reprogram striatal astrocytes into GABA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72fa73c609d0f78595af35eb21962ab
https://doaj.org/article/2387e888eee84d4b8badfe7bc66564ae
https://doaj.org/article/2387e888eee84d4b8badfe7bc66564ae
Autor:
Gregory J. Quirk, Grace Lee, Susan Keefe, Angélica Minier-Toribio, Kathryn Lee, Yuchen Chen, Gong Chen, Yuting Bai, Zi Fei Pei, Zheng Wu, Emma Yellin, Fabricio H. Do-Monte, Jiu Chao Yin, Miranda Chen, Ning Xin Ma, Yi Hu
Publikováno v:
Mol Ther
Adult mammalian brains have largely lost neuroregeneration capability except for a few niches. Previous studies have converted glial cells into neurons, but the total number of neurons generated is limited and the therapeutic potential is unclear. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a04a46f931f8dce5b8d78b73de2f146a
https://pubmed.ncbi.nlm.nih.gov/35123656
https://pubmed.ncbi.nlm.nih.gov/35123656
Autor:
Yi Hu, Jiu Chao Yin, Fabricio H. Do-Monte, Grace Lee, Gregory J. Quirk, Miranda Chen, Yuchen Chen, Pengqian Huang, Emma Yellin, Zi Fei Pei, Zheng Wu, Angélica Minier-Toribio, Yuting Bai, Gong Chen, Kathryn Lee, Ning Xin Ma
Mammalian brains have largely lost internal neural regeneration capability except for a few discrete neurogenic niches. After brain injury, the cerebral cortex is especially difficult to repair due to its extremely low rate of adult neurogenesis. Pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abdaa42ea25b8ef64004f5de075f5b79
