Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Zhuoya Wan"'
Autor:
Zhangyi Luo, Zhuoya Wan, Pengfei Ren, Bei Zhang, Yixian Huang, Raymond E. West III, Haozhe Huang, Yuang Chen, Thomas D. Nolin, Wen Xie, Junmei Wang, Song Li, Jingjing Sun
Publikováno v:
Advanced Science, Vol 11, Iss 19, Pp n/a-n/a (2024)
Abstract PARP inhibitors (PARPi)‐based synthetic lethal therapy demonstrates limited efficacy for most cancer types that are homologous recombination (HR) proficient. To potentiate the PARPi application, a nanocarrier based on 5‐azacytidine (AZA)
Externí odkaz:
https://doaj.org/article/b2caf4858ed14f1e9a64d644c6e27234
Autor:
Jianxia Dong, Xueru Zhou, Qing Li, Ruohui Zheng, Jing Chen, Yuzhe Liu, Xin Tong, Zhuoya Wan, Tao Gong
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 875 (2024)
Implantable drug delivery systems formed upon injection offer a host of advantages, including localized drug administration, sustained release, minimized side effects, and enhanced patient compliance. Among the various techniques utilized for the dev
Externí odkaz:
https://doaj.org/article/2ec0f2e15bf44eaba7e6f5024eb7c675
Autor:
Pearl Moharil, Zhuoya Wan, Apurva Pardeshi, Jiang Li, Haozhe Huang, Zhangyi Luo, Sanjay Rathod, Ziqian Zhang, Yuang Chen, Bei Zhang, Christian A. Fernandez, Jingjing Sun, Song Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 3, Pp 1148-1162 (2022)
Combination of passive targeting with active targeting is a promising approach to improve the therapeutic efficacy of nanotherapy. However, most reported polymeric systems have sizes above 100 nm, which limits effective extravasation into tumors that
Externí odkaz:
https://doaj.org/article/02bac7177ba24ca8add70df186fd4e49
Autor:
Yuang Chen, Yixian Huang, Haozhe Huang, Zhangyi Luo, Ziqian Zhang, Runzi Sun, Zhuoya Wan, Jingjing Sun, Binfeng Lu, Song Li
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 594-602 (2021)
Cancer vaccines that make use of tumor antigens represent a promising therapeutic strategy by stimulating immune responses against tumors to generate long-term anti-tumor immunity. However, vaccines have shown limited clinical efficacy due to ineffic
Externí odkaz:
https://doaj.org/article/27c3f140bced46b3b1d58ff69b9bb23e
Publikováno v:
Molecules, Vol 26, Iss 5, p 1220 (2021)
Cancer immunotherapies have generated some miracles in the clinic by orchestrating our immune system to combat cancer cells. However, the safety and efficacy concerns of the systemic delivery of these immunostimulatory agents has limited their applic
Externí odkaz:
https://doaj.org/article/b6a3c5b02a2a403c8f5e22e7d0ac0819
Autor:
Zhuoya Wan, Haozhe Huang, Raymond E. West III, Min Zhang, Bei Zhang, Xinran Cai, Ziqian Zhang, Zhangyi Luo, Yuang Chen, Yue Zhang, Wen Xie, Da Yang, Thomas D. Nolin, Junmei Wang, Song Li, Jingjing Sun
Publikováno v:
Materials Today. 62:33-50
Autor:
Jingchen Zhai, Xibing He, Yuchen Sun, Zhuoya Wan, Beihong Ji, Shuhan Liu, Song Li, Junmei Wang
Publikováno v:
Physical Chemistry Chemical Physics. 24:18291-18305
Development of mGLUR4/mGLUR8 target-specific scoring functions for drug lead identification through virtual screenings.
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The Apple polysaccharides (AP), extracted from the fruit of apple, has been used to treat multiple pathological diseases. In this study, we evaluated the effects of AP on cognitive impairment and intestinal aging in naturally aging mice. As
Externí odkaz:
https://doaj.org/article/1ff6678f0c4544eda9bf81da05cdd7fd
Autor:
Ziqian Zhang, Yixian Huang, Haozhe Huang, Jingjing Sun, Song Li, Binfeng Lu, Runzi Sun, Yuang Chen, Zhangyi Luo, Zhuoya Wan
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 26, Iss, Pp 594-602 (2021)
Molecular Therapy: Nucleic Acids, Vol 26, Iss, Pp 594-602 (2021)
Cancer vaccines that make use of tumor antigens represent a promising therapeutic strategy by stimulating immune responses against tumors to generate long-term anti-tumor immunity. However, vaccines have shown limited clinical efficacy due to ineffic
Publikováno v:
Journal of Leukocyte Biology. 109:425-436
In the past decade, clinical and laboratory studies have led to important new insights into the biology of leukemia and its treatment. This review describes the progress of leukemia research in the United States in recent years. Whereas the tradition