Allospecific CD8 T suppressor cells induced by multiple MLC stimulation or priming in the presence of ILT3.Fc have similar gene expression profiles

Autor: Yun Luo, Sophey Ho, Chris Chang, George Vlad, Zhuoru Liu, Ling Chen, Raffaello Cortesini, Raphael Clynes, Nicole Suciu-Foca, Zheng Xu

Publikováno v: Human Immunology. 75:190-196

Alloantigen specific CD8 T suppressor cells can be generated in vitro either by multiple stimulations of CD3 T cells with allogeneic APC or by single stimulation in primary MLC containing recombinant ILT3.Fc protein. The aim of the present study was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfdbf6584018946a29419ababbc30f03
https://doi.org/10.1016/j.humimm.2013.10.004

BCL6 Is Required for Differentiation of Ig-Like Transcript 3-Fc–Induced CD8+ T Suppressor Cells

Autor: Piotr Witkowski, Raffaello Cortesini, Michael B. Stokes, George Vlad, Chih-Chao Chang, Qing-Yin Zhang, Eric K. Ho, Zhuoru Liu, Ali Torkamani, Vivette D. D'Agati, Nicole Suciu-Foca

Publikováno v: The Journal of Immunology. 185:5714-5722

Ig-like transcript 3 (ILT3) is an inhibitory receptor expressed by tolerogenic dendritic cells. When human CD8+ T cells are allostimulated in the presence of recombinant ILT3-Fc protein, they differentiate into antigenic specific T suppressor (Ts) ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1061bafe022fdb5096d13afbe75fa65
https://doi.org/10.4049/jimmunol.1001732

Anti-CD25 treatment and FOXP3-positive regulatory T cells in heart transplantation

Autor: J.W. Cai, Jianshe Fan, Zhuoru Liu, Zhezhen Jin, Raffaello Cortesini, Elizabeth Burke, Eric K. Ho, Silviu Itescu, Nicole Suciu-Foca, George Vlad, Mario C. Deng, Elena R. Vasilescu, Charles C. Marboe, Martin Cadeiras, Donna Mancini

Publikováno v: Transplant Immunology. 18:13-21

The interleukin-2 receptor alpha chain (IL-2Ra, CD25) plays a major part in shaping the dynamics of T cell populations following immune activation, due to its role in T cell proliferation and survival. Strategies to blunt the effector responses in tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01bc2ef1547d5335e1da302ed20ef70
https://doi.org/10.1016/j.trim.2007.03.001

Two-Layer Method in Short-Term Pancreas Preservation for Successful Islet Isolation

Autor: E. Poumian-Ruiz, Simona Cernea, Piotr Witkowski, Q. Guo, Kevan C. Herold, Mark A. Hardy, Zhuoru Liu

Publikováno v: Transplantation Proceedings. 37:3398-3401

We sought to determine whether the two-layer method (TLM) offers advantages over UW storage solution for locally procured pancreata with cold ischemia time of8 hours for successful islet isolation.From October 2003 through February 2005, 22 human pan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af21696a8aa880af8019ed13723fa440
https://doi.org/10.1016/j.transproceed.2005.09.050

Identification of Tissue-Restricted Transcripts in Human Islets

Autor: Kevan C. Herold, Zhuoru Liu, Federica Moschella, Piotr Witkowski, Giovanna Del Pozzo, Eric Minwei Liu, Antonella Maffei, Paul L. Harris, Robert Winchester, Mark A. Hardy

Publikováno v: Endocrinology (Philadelphia) 145 (2004): 4513–4521. doi:10.1210/en.2004-0691
info:cnr-pdr/source/autori:Maffei A.; Liu Z.; Witkowski P.; Moschella F.; Del Pozzo G.; Liu E.; Herold K.; Winchester R.J.; Hardy M.A. and Harris P.E./titolo:Identification of Tissue Restricted Transcripts in Human Islets/doi:10.1210%2Fen.2004-0691/rivista:Endocrinology (Philadelphia)/anno:2004/pagina_da:4513/pagina_a:4521/intervallo_pagine:4513–4521/volume:145

The purpose of our study was to identify transcripts specific for tissue-restricted, membrane-associated proteins in human islets that, in turn, might serve as markers of healthy or diseased islet cell masses. Using oligonucleotide chips, we obtained

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f231f2681ef57c8e680f7d873b12be
https://doi.org/10.1210/en.2004-0691