Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Zhuomei Lu"'
Supplementary Data from 3-Phosphoinositide–Dependent Protein Kinase-1 Regulates Proliferation and Survival of Cancer Cells with an Activated Mitogen-Activated Protein Kinase Pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144b149a15569bb22e5cfb1913e41a0e
https://doi.org/10.1158/1541-7786.22519194.v1
https://doi.org/10.1158/1541-7786.22519194.v1
Publikováno v:
Molecular Cancer Research. 8:421-432
Engagement of cell surface receptor tyrosine kinases by insulin and growth factors activates phosphatidylinositol 3-kinase (PI3K) and generates the second messenger, phosphatidylinositol 3,4,5-trisphosphate. This second messenger leads to the recruit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5b4baf9818c04cf5738cb925a9d7c2
https://doi.org/10.1158/1541-7786.mcr-09-0179
https://doi.org/10.1158/1541-7786.mcr-09-0179
Autor:
Joseph E. Myers, Zhizhang Yin, Ahmed A. Samatar, William T. Windsor, Rosalinda Syto, Zhuomei Lu, Sandra Koseoglu, C. Chandra Kumar, Paul Kirschmeier, Todd Mayhood, Jill M. Stafford, Tammy C. Turek-Etienne, Linda James, Bruce A. Malcolm
Publikováno v:
SLAS Discovery. 9:309-321
Most of the protein kinase inhibitors being developed are directed toward the adenosine triphosphate (ATP) binding site that is highly conserved in many kinases. A major issue with these inhibitors is the specificity for a given kinase. Structure det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46773bef802fc568f62c01c68ef19547
https://doi.org/10.1177/1087057104263506
https://doi.org/10.1177/1087057104263506
Publikováno v:
University of Copenhagen
Skeletal muscle has a nonconventional Golgi complex (GC), the organization of which has been a subject of controversy in the past. We have now examined the distribution of the GC by immunofluorescence and immunogold electron microscopy in whole fiber
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ed52774000faaa00a12ddff62c80bd
https://doi.org/10.1523/jneurosci.19-24-10694.1999
https://doi.org/10.1523/jneurosci.19-24-10694.1999
Publikováno v:
Journal of Neurocytology. 27:411-418
Protocols for in situ hybridization (ISH) of cultured cells often include storage in alcohol at −20°C between fixation of the cultures and the ISH procedure. In experiments aimed at localizing ferritin mRNA in C2 muscle cultures by ISH with digoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0991f645f779ab664fe8d894fbca775
https://doi.org/10.1023/a:1006932426837
https://doi.org/10.1023/a:1006932426837
Publikováno v:
IUBMB Life. 40:217-233
Based on the rationale that internalized 2-deoxy-D-glucose (dGlc) is toxic to cells, glucose transport (GLUT) defective myoblast mutants have been isolated by their ability to grow in glucose-free medium containing dGlc. Recent studies revealed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898655258634b90ca63d8d778fd38be6
https://doi.org/10.1080/15216549600201712
https://doi.org/10.1080/15216549600201712
Publikováno v:
Cancer biologytherapy. 6(5)
AKT is a key serine/threonine kinase in the PTEN/PI3K/AKT pathway(1) and activationof AKT is often observed in human cancers. To explore the role of AKT in cell survival in different tumor cells, we tested 20 human tumor cell lines for response to kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d076f5bf78e0d7b76315ba2c2d00beb
https://pubmed.ncbi.nlm.nih.gov/17426444
https://pubmed.ncbi.nlm.nih.gov/17426444
Publikováno v:
Molecular biology of the cell. 12(4)
During skeletal muscle differentiation, the Golgi complex (GC) undergoes a dramatic reorganization. We have now visualized the differentiation and fusion of living myoblasts of the mouse muscle cell line C2, permanently expressing a mannosidase-green
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18cce173e90a81c5c4a96d8da7e4329
https://pubmed.ncbi.nlm.nih.gov/11294887
https://pubmed.ncbi.nlm.nih.gov/11294887
Publikováno v:
Molecular and cellular neurosciences. 12(6)
In neurons, mRNAs are differentially sorted to axons, dendrites, and the cell body. Recently, regions of certain mRNAs have been identified that target those mRNAs for translocation to the processes. However, the mechanism by which many, if not most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96041e16a4fdecb6affd1812f0511aa0
https://pubmed.ncbi.nlm.nih.gov/9888989
https://pubmed.ncbi.nlm.nih.gov/9888989
Publikováno v:
Biochimica et biophysica acta. 1234(2)
Rat L6 myoblasts were recently shown to possess the GLUT 1, 3 and 4 transporters, and not the GLUT 2 isoform [1]. This investigation examined the expression and properties of the GLUT 1 isoform. GLUT 1 transcript level was significantly reduced in ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f014bb4a94f2af24f7ae483a020781f2
https://pubmed.ncbi.nlm.nih.gov/7696290
https://pubmed.ncbi.nlm.nih.gov/7696290