Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Zhuokai Zhuang"'
Autor:
Peisi Li, Dawang Zhou, Yumo Xie, Ze Yuan, Mingzhe Huang, Gaopo Xu, Junfeng Huang, Zhuokai Zhuang, Yanxin Luo, Huichuan Yu, Xiaolin Wang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 11, Pp 1-10 (2024)
Abstract G-quadruplex (G4) is a noncanonical DNA secondary structure known to induce DNA damage and regulate the expression of immune-related genes. We aim to exploit the G4 folding as a treatment strategy to trigger anti-tumor immune response. In th
Externí odkaz:
https://doaj.org/article/b53b6fc60c694b14991ff661020377d0
Autor:
Zhuokai Zhuang, Jinxin Lin, Zixiao Wan, Jingrong Weng, Ze Yuan, Yumo Xie, Zongchao Liu, Peiyi Xie, Siyue Mao, Zongming Wang, Xiaolin Wang, Meijin Huang, Yanxin Luo, Huichuan Yu
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background The radiogenomic analysis has provided valuable imaging biomarkers with biological insights for gliomas. The radiogenomic markers for molecular profile such as DNA methylation remain to be uncovered to assist the molecular diagnos
Externí odkaz:
https://doaj.org/article/f55e31d92a884c60a69b28a048c57258
Autor:
Dingcheng Shen, Puning Wang, Yumo Xie, Zhuokai Zhuang, Mingxuan Zhu, Xiaolin Wang, Meijin Huang, Yanxin Luo, Huichuan Yu
Publikováno v:
Cancer Medicine, Vol 12, Iss 3, Pp 3433-3441 (2023)
Abstract Background The incidence of colorectal cancer is increasing among young adults and more rectal cancers are reported. This study aimed to identify the clinical features specific for early‐onset rectal cancer and provide insights on cancer m
Externí odkaz:
https://doaj.org/article/1685ce8406054de1aa3880411e45ab34
Autor:
Dingcheng Shen, Jinxin Lin, Yumo Xie, Zhuokai Zhuang, Gaopo Xu, Shaoyong Peng, Guannan Tang, Liangliang Bai, Mingxuan Zhu, Yu Zhang, Ziying Huang, Puning Wang, Xiaoxia Liu, Meijin Huang, Yanxin Luo, Xiaolin Wang, Huichuan Yu
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 5, Pp n/a-n/a (2023)
Abstract Background N6‐methyladenosine (m6A) modification is an emerging epigenetic regulatory mechanism in tumourigenesis. Considering that AlkB homolog 5 (ALKBH5) is a well‐described m6A demethylase in previous enzyme assays, we aimed to invest
Externí odkaz:
https://doaj.org/article/27155b25e31349d6a242d8514f8c0397
Publikováno v:
Heliyon, Vol 9, Iss 2, Pp e13094- (2023)
Neoadjuvant systemic treatment before surgery is a prevalent regimen in the patients with advanced-stage or high-risk tumor, which has shaped the treatment strategies and cancer survival in the past decades. However, some patients present with poor r
Externí odkaz:
https://doaj.org/article/df2d310b8fd54699a574fe41f86674ca
Autor:
Juan Li, Yumo Xie, Ziying Huang, Dingcheng Shen, Zhuokai Zhuang, Mingxuan Zhu, Yaoyi Huang, Rongzhao He, Xiaolin Wang, Meijin Huang, Yanxin Luo, Huichuan Yu
Publikováno v:
Cancer Medicine, Vol 10, Iss 24, Pp 8924-8933 (2021)
Abstract Objective We conducted this multicenter cohort study to evaluate the current tumor‐node‐metastasis staging system and treatment modality by analyzing the survival outcomes of patient groups with stage III and IV colon cancer. Patients an
Externí odkaz:
https://doaj.org/article/bef7f7f1e752494fbba4495b7170dc19
Autor:
Zhuokai Zhuang, Zongchao Liu, Juan Li, Xiaolin Wang, Peiyi Xie, Fei Xiong, Jiancong Hu, Xiaochun Meng, Meijin Huang, Yanhong Deng, Ping Lan, Huichuan Yu, Yanxin Luo
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-10 (2021)
Abstract Background We aimed to develop a radiomic model based on pre-treatment computed tomography (CT) to predict the pathological complete response (pCR) in patients with rectal cancer after neoadjuvant treatment and tried to integrate our model w
Externí odkaz:
https://doaj.org/article/eb3bb4b4d48c49908fd31fb0da285a79
Autor:
Dingcheng Shen, Puning Wang, Yumo Xie, Zhuokai Zhuang, Mingxuan Zhu, Xiaolin Wang, Meijin Huang, Yanxin Luo, Huichuan Yu
Publikováno v:
Cancer Medicine. 12
Autor:
Mingxuan Zhu, Zhuokai Zhuang, Yumo Xie, Ziying Huang, Yaoyi Huang, Dingcheng Shen, Juan Li, Huichuan Yu, Yanxin Luo, Xiaolin Wang, Rongzhao He, Meijin Huang
Publikováno v:
Cancer Medicine, Vol 10, Iss 24, Pp 8924-8933 (2021)
Cancer Medicine
Cancer Medicine
Objective We conducted this multicenter cohort study to evaluate the current tumor‐node‐metastasis staging system and treatment modality by analyzing the survival outcomes of patient groups with stage III and IV colon cancer. Patients and Methods
Autor:
Zenghong Huang, Yumo Xie, Liangliang Bai, Puning Wang, Du Cai, Huichuan Yu, Tang Guannan, Meijin Huang, Xiaolin Wang, Yanxin Luo, Jianping Wang, Jinxin Lin, Qi Zou, Zhuokai Zhuang
Publikováno v:
Diseases of the Colon & Rectum. 64:1321-1330
Background The local recurrence of rectal cancer has been improved by total mesorectal excision following neoadjuvant chemoradiotherapy. However, in patients with low locally advanced rectal cancer, lateral pelvic recurrence remains to be addressed.