Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Zhuojia, Chen"'
Autor:
Ning WAN, Bing WANG, Ya GUO, Zijian HE, Chen YANG, Ning YANG, Liqing LU, Hongyi LIANG, Weibin XIAO, Dandan YANG, Zhuojia CHEN, Wenfeng FANG, Weiting LIANG
Publikováno v:
Chinese Journal of Lung Cancer, Vol 27, Iss 10, Pp 745-754 (2024)
Background and objective Pembrolizumab (PEM) has been shown to be effective in clinical trials for the treatment of advanced non-small cell lung cancer (NSCLC), but clinical trials were based on cohorts of patients selected on specific criteria, and
Externí odkaz:
https://doaj.org/article/f7e48e213b3349f69dc96ca4e441ba7e
Autor:
Weiting Liang, Zhijun Guo, Yunhui Zhang, Ning Yang, Chenchen Guo, Tao Liu, Hongbing Huang, Zhuojia Chen
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 361-369 (2024)
Introduction: Cadonilimab (AK104) is an innovative human programmed cell death-1 (PD-1)/cytotoxic T lymphocyte antigen-4 (CTLA-4) bispecific antibody. Compared with the combination therapy of PD-1 and CTLA-4 blockers, less cellular toxicity of cadoni
Externí odkaz:
https://doaj.org/article/5f2dba4a7ba04cc9807b3e8d48701a60
Autor:
Hongsheng Wang, Qianqian Deng, Ziyan Lv, Yuyi Ling, Xue Hou, Zhuojia Chen, Xiaoxiao Dinglin, Shuxiang Ma, Delan Li, Yingmin Wu, Yanxi Peng, Hongbing Huang, Likun Chen
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/200f8d01afb740058e0b71ccecc51fab
Autor:
Zihan Li, Yanxi Peng, Jiexin Li, Zhuojia Chen, Feng Chen, Jian Tu, Shuibin Lin, Hongsheng Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Dysregulation of N6-Methyladenosine (m6A) is associated with cancer progression. Here, authors show that m6A methylation of pyruvate dehydrogenase kinase 4 (PDK4) positively regulates its mRNA stability and translation, and consequently affects glyco
Externí odkaz:
https://doaj.org/article/8ad24c716e8548f1a29032ce576d9050
Autor:
Shu Liu, Zhao Wang, Rongxin Chen, Xueding Wang, Xiaojie Fang, Zhuojia Chen, Shaoxing Guan, Tao Liu, Tongyu Lin, Min Huang, He Huang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Individual variations in concentrations of rituximab in different B cell non-Hodgkin’s lymphoma subtypes and their relevance to efficacy were still unclear. From 2016 to 2021, a prospective clinical trial was conducted, and 510 samples with 6 uncom
Externí odkaz:
https://doaj.org/article/59212698d3fa4281b869a35ec9c8b964
Autor:
Hongsheng Wang, Qianqian Deng, Ziyan Lv, Yuyi Ling, Xue Hou, Zhuojia Chen, Xiaoxiao Dinglin, Shuxiang Ma, Delan Li, Yingmin Wu, Yanxi Peng, Hongbing Huang, Likun Chen
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-17 (2019)
Abstract Background Brain metastasis (BM) is one of the principal causes of mortality for lung cancer patients. While the molecular events that govern BM of lung cancer remain frustrating cloudy. Methods The miRNA expression profiles are checked in t
Externí odkaz:
https://doaj.org/article/4d40760a22f94683ba13296d57200fbb
Autor:
Yingmin Wu, Xiangling Yang, Zhuojia Chen, Lin Tian, Guanmin Jiang, Feng Chen, Jiexin Li, Panpan An, Linlin Lu, Nan Luo, Jun Du, Hong Shan, Huanliang Liu, Hongsheng Wang
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-16 (2019)
Abstract Background Long noncoding RNAs (lncRNAs) have emerged as critical players in cancer progression, but their functions in colorectal cancer (CRC) metastasis have not been systematically clarified. Methods lncRNA expression profiles in matched
Externí odkaz:
https://doaj.org/article/e11e3f522dfb4d54a99dd3a1ec5b6403
Autor:
Peiyao Lu, Weiting Liang, Jiahao Li, Yanming Hong, Zhuojia Chen, Tao Liu, Pei Dong, Hongbing Huang, Tiantian Zhang, Jie Jiang
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundCompared with the standard of care with sunitinib, avelumab plus axitinib can increase progression-free survival in the first-line of advanced renal cell carcinoma (RCC), but the economic effect of the treatment is unknown. The purpose of t
Externí odkaz:
https://doaj.org/article/d1212dd3b3464752865f599beeb11813
Autor:
Qiao Liu, Zhuojia Chen, Guanmin Jiang, Yan Zhou, Xiangling Yang, Hongbin Huang, Huanliang Liu, Jun Du, Hongsheng Wang
Publikováno v:
Molecular Cancer, Vol 16, Iss 1, Pp 1-14 (2017)
Abstract Background Estrogenic signals are suggested to have protection roles in the development of colorectal cancer (CRC). The G protein-coupled estrogen receptor (GPER) has been reported to mediate non-genomic effects of estrogen in hormone relate
Externí odkaz:
https://doaj.org/article/3cd53888cce6413f9974f7bcb519980c
Autor:
Haisheng Zhang, Jiawang Zhou, Jiexin Li, Zhaotong Wang, Zhuojia Chen, Ziyan Lv, Lichen Ge, Guoyou Xie, Guoming Deng, Yalan Rui, Hongbing Huang, Likun Chen, Hongsheng Wang
Publikováno v:
Cancer Research.
Angiogenesis is hijacked by cancer to support tumor growth. RNA modifications such as N6-methyladenosine (m6A) can regulate several aspects of cancer, including angiogenesis. Here, we find that m6A triggers angiogenesis in lung cancer by upregulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2873a103f227b05e7adb1fd80380dbca
https://doi.org/10.1158/0008-5472.can-22-2449
https://doi.org/10.1158/0008-5472.can-22-2449