Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Zhuohong Yan"'
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28126- (2024)
The T cell immunoglobulin and mucin-domain containing-3 (TIM-3) receptor has gained significant attention as a promising target for cancer immunotherapy. The inhibitory effect of T cells by TIM-3 is mediated through the interaction between TIM-3 and
Externí odkaz:
https://doaj.org/article/b437ccfb2f4840968234b63e85dcab76
Autor:
Ling Yi, Xiaojue Wang, Siyun Fu, Zhuohong Yan, Tianyu Ma, Siqi Li, Panjian Wei, Hongtao Zhang, Jinghui Wang
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract In this study, we explored the dynamic changes in blood sPD-L1 and its clinical value during anti-PD-1 immunotherapy in non-small cell lung cancer (NSCLC) patients. First, we established a sandwich ELISA for functional sPD-L1 that can bind t
Externí odkaz:
https://doaj.org/article/23dca0f88b744e8a98bda0990375fc09
Autor:
Zhuohong Yan, Jinghui Wang, Yu Pang, Xiaojue Wang, Ling Yi, Panjian Wei, Hongyun Ruan, Meng Gu, Hongtao Zhang, Xinting Yang
Publikováno v:
Microorganisms, Vol 11, Iss 9, p 2259 (2023)
Tuberculous pleurisy (TP) is one of the most common forms of extrapulmonary tuberculosis, but its diagnosis is challenging. Lipoarabinomannan (LAM) antigen is a biomarker for Mycobacterium tuberculosis (Mtb) infection. LAM detection has potential as
Externí odkaz:
https://doaj.org/article/dc2edb72b6564e5cb5f8ed76533c5366
Autor:
Shuping Li, Ling Yi, Xiqing Wei, Jinguo Zhang, Xiaojue Wang, Chang Jiang, Zhuohong Yan, Liwei Song, Bin Yang, Panjian Wei, Xiang Gao, Jinghui Wang, Hongtao Zhang, Jian Zhang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundSoluble programmed cell death-ligand 1 (sPD-L1) has been well documented to activate immunosuppression and is considered an essential predictor of negative clinical outcomes for several malignances and inflammatory conditions. However, the
Externí odkaz:
https://doaj.org/article/ea72fd097b3f4b39aa4b0577e55c2502
Autor:
Ling Yi, Xin Jin, Jinghui Wang, Zhuohong Yan, Xu Cheng, Tao Wen, Bin Yang, Xiaojue Wang, Nanying Che, Zhidong Liu, Hongtao Zhang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Negative immune regulation plays a notable role in tumor immunity. This study aimed to confirm that CD137 mediates negative immunoregulation as well as agonist activity in tumor immunity. Soluble CD137 (sCD137), a prominent splice variant of membrane
Externí odkaz:
https://doaj.org/article/d7dc568847aa4baaa099cc0e9e2e7273
Autor:
Helin Wang, Zhuohong Yan, Jianqing Hao, Bin Yang, Jinghui Wang, Ling Yi, Xiaojue Wang, Shuping Li, Hongtao Zhang, Shucai Zhang
Publikováno v:
Thoracic Cancer, Vol 10, Iss 12, Pp 2225-2235 (2019)
Abstract Background The expression of PD‐L1 and its regulation in tumors remains unclear. The importance of IFN‐γ in upregulating the PD‐L1 expression in various tumors, and the effects of other essential cytokines in the tumor microenvironmen
Externí odkaz:
https://doaj.org/article/8fbbfc1f1d99497286dca429b026cc92
Autor:
Zhuohong Yan, Xiaojue Wang, Ling Yi, Bin Yang, Panjian Wei, Hongyun Ruan, Jinghui Wang, Xinting Yang, Hongtao Zhang
Publikováno v:
Pathogens, Vol 11, Iss 12, p 1545 (2022)
For the rapid, reliable, and cost-effective methods of tuberculosis (TB) auxiliary diagnosis, antibody (Ab) detection to multiple antigens of Mycobacterium tuberculosis (Mtb) has great potential; however, this methodology requires optimization. We co
Externí odkaz:
https://doaj.org/article/64f4b72e030845b6afff6eee1a08567b
Autor:
Xiaojue Wang, Hongyan Jia, Panjian Wei, Zhuohong Yan, Yanlin Zhao, Bin Yang, Yu Pang, Ling Yi, Helin Wang, Hongtao Zhang, Bing Zhao, Shuping Li
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 54, Iss 3, Pp 437-446 (2021)
Background/purpose The World Health Organization has recommended commercial urine-sourced lipoarabinomannan (LAM) detection as a tool for screening HIV patients with suspected TB, but more sensitive immunodetection assays would help to identify HIV-n
Autor:
Hongmei Chen, Shanshan Li, Weijie Zhao, Jiaheng Deng, Zhuohong Yan, Tingting Zhang, Shu' an Wen, Haiping Guo, Lei Li, Jianfeng Yuan, Hongtao Zhang, Liping Ma, Jianhua Zheng, Mengqiu Gao, Yu Pang
Publikováno v:
Infection and drug resistance. 15
Hongmei Chen,1,* Shanshan Li,2,* Weijie Zhao,3,* Jiaheng Deng,4,* Zhuohong Yan,5 Tingting Zhang,2 Shuâ an Wen,2 Haiping Guo,2 Lei Li,6 Jianfeng Yuan,6 Hongtao Zhang,5 Liping Ma,1 Jianhua Zheng,4,* Mengqiu Gao,1 Yu Pang2 1Depa
Autor:
Tianyu Ma, Tao Wen, Xu Cheng, Yuxuan Wang, Panjian Wei, Bing Yang, Ling Yi, Xiaojue Wang, Zhuohong Yan, Jinghui Wang, Zhidong Liu
Publikováno v:
SSRN Electronic Journal.
Neoadjuvant chemo-immunotherapy has got clinical benefits in parts of resectable non-small cell lung cancer (NSCLC) patients. The factors affecting the pathological response of NSCLC remain controversial.A retrospective study of 59 patients with rese