Zobrazeno 1 - 10
of 653
pro vyhledávání: '"Zhuo Wan"'
Autor:
Jun Jiang, Yuan Lu, Jie Chu, Xiao Zhang, Chao Xu, Shaojie Liu, Zhuo Wan, Jiawei Wang, Lu Zhang, Kui Liu, Zhenhua Liu, Angang Yang, Xinling Ren, Rui Zhang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Brain metastasis (BM) is one of the leading causes of cancer-related deaths in patients with advanced non-small cell lung cancer (NSCLC). However, limited treatments are available due to the presence of the blood-brain barrier (BBB). Upregul
Externí odkaz:
https://doaj.org/article/e78b7e45e8924488bbe6bf5490ca497e
Autor:
Wei Zhang, Zhuo Wan, Di Qu, Wenqi Sun, Liang Zhang, Yuan Liang, Lei Pan, Hua Jiang, Zichen Ye, Mengying Wei, Lijun Yuan, Guodong Yang, Faguang Jin
Publikováno v:
Bioactive Materials, Vol 32, Iss , Pp 488-501 (2024)
Pulmonary fibrosis (PF) is a devastating lung disease with limited treatment options. During this pathological process, the profibrogenic macrophage subpopulation plays a crucial role, making the characterization of this subpopulation fundamentally i
Externí odkaz:
https://doaj.org/article/2f97cdc1edb147eaa897b10001c4b1d1
Autor:
Ruiyan Mei, Zhuo Wan, Cheng Yang, Xiangjing Shen, Ronglin Wang, Haihua Zhang, Rui Yang, Junqiang Li, Yang Song, Haichuan Su
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
In recent years, cell therapy has provided desirable properties for promising new drugs. Mesenchymal stem cells are promising candidates for developing genetic engineering and drug delivery strategies due to their inherent properties, including immun
Externí odkaz:
https://doaj.org/article/3b0da5177e6b4725a53013c0f855da2b
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
FLT3-ITD is a type of poor prognostic factors in acute myeloid leukemia (AML) disease. Gilteritinib, the second-generation FLT3 tyrosine kinase inhibitor, improved the overall survival of patients with relapsed/refractory FLT3-mutated AML in the ADMI
Externí odkaz:
https://doaj.org/article/dc73fdbc10a1458bb84ffdebd0482c4b
Autor:
Yuting Feng, Shuyi Wang, Xiaoye Liu, Yiming Han, Hongwei Xu, Xiaocen Duan, Wenyue Xie, Zhuoling Tian, Zuoying Yuan, Zhuo Wan, Liang Xu, Siying Qin, Kangmin He, Jianyong Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Cells living in geometrically confined microenvironments are ubiquitous in various physiological processes, e.g., wound closure. However, it remains unclear whether and how spatially geometric constraints on host cells regulate bacteria-host
Externí odkaz:
https://doaj.org/article/907421de5fef4f40aeb6cfffe49b6165
Autor:
Zuoying Yuan, Xiaocen Duan, Xing Su, Zhuoling Tian, Anqi Jiang, Zhuo Wan, Hao Wang, Pengfei Wei, Bo Zhao, Xiaozhi Liu, Jianyong Huang
Publikováno v:
Bioactive Materials, Vol 21, Iss , Pp 566-575 (2023)
Biological receptor-ligand adhesion governed by mammalian cells involves a series of mechanochemical processes that can realize reversible, loading rate-dependent specific interfacial bonding, and even exhibit a counterintuitive behavior called catch
Externí odkaz:
https://doaj.org/article/e91b07b59aa44a4e8125198c034cb284
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 702-713 (2022)
Prostate cancer (PCa) responds poorly to routine immunotherapy due to the tumor immunosuppressive microenvironment. Here, we describe an ultrasound-based drug delivery strategy to stimulate potent anti-tumor immunity via exosomes encapsulated with so
Externí odkaz:
https://doaj.org/article/6dec4a87338848139d86c7f247a28e24
Autor:
Tingting Wang, Yan Dong, Li Yao, Fan Lu, Chenxi Wen, Zhuo Wan, Li Fan, Zhelong Li, Te Bu, Mengying Wei, Xuekang Yang, Yi Zhang
Publikováno v:
Bioactive Materials, Vol 16, Iss , Pp 82-94 (2022)
Atherosclerosis is characterized by inflammation in the arterial wall, which is known to be exacerbated by diabetes. Therapeutic repression of inflammation is a promising strategy for treating atherosclerosis. In this study, we showed that diabetes a
Externí odkaz:
https://doaj.org/article/332980c8b6ff4a1da56d71915ea1a50b
Autor:
Yike Gao, Zuoying Yuan, Xiaojing Yuan, Zhuo Wan, Yingjie Yu, Qi Zhan, Yuming Zhao, Jianmin Han, Jianyong Huang, Chunyang Xiong, Qing Cai
Publikováno v:
Bioactive Materials, Vol 14, Iss , Pp 377-388 (2022)
Exosomes derived from mesenchymal stem cells (MSCs) have demonstrated regenerative potential for cell-free bone tissue engineering, nevertheless, certain challenges, including the confined therapeutic potency of exosomes and ineffective delivery meth
Externí odkaz:
https://doaj.org/article/f4b81ea56e2e4789a19117914e7d7671
Autor:
Zhuo Wan, Xueqi Gan, Ruiyan Mei, Jianbin Du, Wen Fan, Mengying Wei, Guodong Yang, Weiwei Qin, Zhuoli Zhu, Li Liu
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Exosomes are recognized as effective platforms for targeted delivery for their high physicochemical stability and biocompatibility. However, most of the exosomes are inevitably and rapidly cleared by mononuclear phagocytic system
Externí odkaz:
https://doaj.org/article/ed771d6709554518ad33fe05f209b7df