Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Zhun Bi"'
Autor:
Yang Miao, Yanhua Wang, Zhun Bi, Kai Huang, Jingjing Gao, Xiaohe Li, Shimeng Li, Luqing Wei, Honggang Zhou, Cheng Yang
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease characterized by alveolar epithelial cell injury and lung fibroblast overactivation. At present, only two drugs are approved by the FDA for the treatment
Externí odkaz:
https://doaj.org/article/877d1d3af1684284b7ea65d76717d765
Autor:
Xiaohe Li, Rui Liu, Yunyao Cui, Jingjing Liang, Zhun Bi, Shimeng Li, Yang Miao, Liang Zhang, Xiaoping Li, Honggang Zhou, Cheng Yang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Pulmonary fibrosis is a known sequela of severe or persistent lung damage. Existing clinical, imaging and autopsy studies have shown that the lungs exhibit a pathological pulmonary fibrosis phenotype after infection with coronaviruses, including seve
Externí odkaz:
https://doaj.org/article/ecbab47a2cfb4fc6bab71b2e711a94d4
Autor:
Shijiao Cai, Zhun Bi, Yunpeng Bai, Heng Zhang, Denghui Zhai, Cui Xiao, Yuanhao Tang, Lan Yang, Xiaoyun Zhang, Kun Li, Ru Yang, Yanrong Liu, Shuang Chen, Tao Sun, Huijuan Liu, Cheng Yang
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
Hepatocellular carcinoma (HCC) is one of the most common malignant cancers with poor prognosis and high incidence. Cancer stem cells play a vital role in tumor initiation and malignancy. The degree of differentiation of HCC is closely related to its
Externí odkaz:
https://doaj.org/article/d61cf4f774e34defaaa7cdd346225c3b
Autor:
Ting Xiao, Qiang Zhang, Shumin Zong, Wei-long Zhong, Yuan Qin, Zhun Bi, Shuang Chen, Hui-juan Liu, Jun-jie Wei, Bi-jiao Zhou, Lu-meng Wang, Hong-gang Zhou, Yan-rong Liu, Tao Sun, Cheng Yang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-11 (2018)
Abstract Background Tumor cells transfer into endothelial cells by epithelial–endothelial transition (EET), which is characterized by vasculagenic mimicry (VM) in morphology. VM can change tumor microcirculation, progression, and metastasis. Howeve
Externí odkaz:
https://doaj.org/article/325efe0578c7452292fcddb01459b155
Autor:
Xiaohe Li, Zhun Bi, Shuaishuai Liu, Shaoyan Gao, Yunyao Cui, Kai Huang, Mengying Huang, Jiahe Mao, Lixin Li, Jingjing Gao, Tao Sun, Honggang Zhou, Cheng Yang
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Idiopathic pulmonary fibrosis (IPF) is a progressive and usually fatal lung disease that is characterized by fibroblast proliferation and extracellular matrix remodeling, which result in irreversible distortion of the lung’s architecture and the fo
Externí odkaz:
https://doaj.org/article/c998dab2fd3c41d4b3c152d13fc2bf08
Autor:
Ming Wang, Shanfa Ren, Zhun Bi, Liang Zhang, Mengqi Cui, Ronghao Sun, Jiali Bao, Dandi Gao, Bo Yang, Xiaoping Li, Mingjiang Li, Ting Xiao, Hong‐gang Zhou, Cheng Yang
Publikováno v:
Phytotherapy Research. 36:1807-1821
Most antiangiogenic inhibitors targeting endothelium-dependent vessels cannot inhibit tumor growth but promote tumor invasion and metastasis in some patients. Vasculogenic mimicry (VM) employs mechanisms that differ from those used to construct endot
Autor:
Liang Zhang, Yuli Wei, Cui Yunyao, Jing-jing Liang, Ma Ling, Xiaohe Li, Wang Yanhua, Zhun Bi, Bingchen Zhou, Hao Ruan, Honggang Zhou, Cheng Yang
Publikováno v:
Phytotherapy Research. 35:5808-5822
Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease characterized by epithelial cell damage, fibroblast activation, and collagen deposition. IPF has high mortality and limited therapies, which urgently needs to develop safe and effectiv
Autor:
Shao Shuaibo, Xiaohe Li, Ruotong Zhang, Hailong Li, Bai Jiakun, Zhun Bi, Liang Zhang, Wen Ning, Yiying Wei, Chunfeng Xie, Cheng Yang, Bowei Ma, Shanshan Zhang, Xiaoyang Ma, Honggang Zhou
Publikováno v:
Journal of Cellular and Molecular Medicine
Liver fibrosis is a disease caused by long‐term damage that is related to a number of factors. The current research on the treatment of liver fibrosis mainly focuses on the activation of hepatic stellate cell, in addition to protecting liver cells.
Autor:
Ting Xiao, Shanfa Ren, Zhun Bi, Dandi Gao, Jiali Bao, Ronghao Sun, Xiaoting Gu, Jingjing Gao, Shanshan Chen, Chunwa Wu, Cheng Yang, Guang Yang, Honggang Zhou
Publikováno v:
SSRN Electronic Journal.
Autor:
Jiahe Mao, Shuaishuai Liu, Chengcheng Su, Zhun Bi, Yujiao Wei, Sheng Pengzhen, Lin Zhao, Luqing Wei, Qi Min, Tao Sun, Shuangwei Liu, Kai Huang, Ning Liu, Cheng Lu, Honggang Zhou, Shaoyan Gao, Xiaohe Li, Guang Yang, Xinhua Liu, Shengxiang Miao, Wen Ning, Cheng Yang, Mengying Huang, Shuanglin Qin, Tongtong Liu, Ting Xiao
Publikováno v:
European Journal of Medicinal Chemistry. 157:229-247
In this study, anti-IPF lead compounds 42 and 44, derived from natural sesquiterpene lactones Isoalantolactone and alantolactone, were discovered by screening from a high-throughput TGF-β1 reporter luciferase assay. Notably, they could reduce the my