Zobrazeno 1 - 10 of 43 pro vyhledávání: '"Zhuanhong Qiao"'
1
Akademický článek
Explicit memory, anxiety and depressive like behavior in mice exposed to chronic intermittent hypoxia, sleep fragmentation, or both during the daylight period
Autor: Clementine Puech, Mohammad Badran, Alexandra R. Runion, Max B. Barrow, Zhuanhong Qiao, Abdelnaby Khalyfa, David Gozal
Publikováno v: Neurobiology of Sleep and Circadian Rhythms, Vol 13, Iss , Pp 100084- (2022)
Obstructive sleep apnea (OSA) is a chronic and highly prevalent condition characterized by chronic intermittent hypoxia (IH) and sleep fragmentation (SF), and can lead to a vast array of end-organ morbidities, particularly affecting cardiovascular, m
Externí odkaz: https://doaj.org/article/348ccb746f144efd83d84aecdadeb5d3
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2
Akademický článek
Exosomes and Metabolic Function in Mice Exposed to Alternating Dark-Light Cycles Mimicking Night Shift Work Schedules
Autor: Abdelnaby Khalyfa, Valeriy A. Poroyko, Zhuanhong Qiao, Alex Gileles-Hillel, Ahamed A. Khalyfa, Mahzad Akbarpour, Isaac Almendros, Ramon Farré, David Gozal
Publikováno v: Frontiers in Physiology, Vol 8 (2017)
Sleep is an important modulator of metabolic function. Disruptions of sleep in circadian rhythm are common in modern societies and are associated with increased risk of developing cardiometabolic disorders. Exosomes are ubiquitous extracellular vesic
Externí odkaz: https://doaj.org/article/38f909857eef48c38d15f40c0e07a38d
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6
Cell-Selective Altered Cargo Properties of Extracellular Vesicles Following In Vitro Exposures to Intermittent Hypoxia
Autor: Leila Kheirandish-Gozal, Jose M. Marin, David Gozal, Abdelnaby Khalyfa, David Sanz-Rubio, Zhuanhong Qiao, Jorge Ullate
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 5604, p 5604 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 22; Issue 11; Pages: 5604
Intermittent hypoxia (IH), a hallmark of obstructive sleep apnea (OSA), is associated with cardiovascular and metabolic dysfunction. However, the mechanisms underlying these morbidities remain poorly delineated. Extracellular vesicles (EVs) mediate i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52bf6ea78d93faf2b52e3d0f6d1d8575
https://www.mdpi.com/1422-0067/22/11/5604
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7
Heterogeneity of Melanoma Cell Responses to Sleep Apnea-Derived Plasma Exosomes and to Intermittent Hypoxia
Autor: Francisco Campos-Rodriguez, Wojciech Trzepizur, Manuel Sánchez-de-la-Torre, Miguel Ángel Martínez-García, Zhuanhong Qiao, Isaac Almendros, Jose M. Marin, David Gozal, Abdelnaby Khalyfa, Alex Gileles-Hillel, David Sanz-Rubio, Francisco García-Río, Ramon Farré
Publikováno v: Repositorio Abierto de la UdL
Universitad de Lleida
Cancers
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Zaguán. Repositorio Digital de la Universidad de Zaragoza
Cancers, Vol 13, Iss 4781, p 4781 (2021)
Volume 13
Issue 19
Obstructive sleep apnea (OSA) is associated with increased cutaneous melanoma incidence and adverse outcomes. Exosomes are secreted by most cells, and play a role in OSA-associated tumor progression and metastasis. We aimed to study the effects of pl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc756f2158cf925a24a58639419e3ea1
https://doi.org/10.3390/cancers13194781
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8
Monocarboxylate Transporter-2 Expression Restricts Tumor Growth in a Murine Model of Lung Cancer: A Multi-Omic Analysis
Autor: Lyndon M. Coghill, Zhuanhong Qiao, Murugesan Raju, Aaron C. Ericsson, Chi-Ren Shyu, David Gozal, Abdelnaby Khalyfa
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 10616, p 10616 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 19
Monocarboxylate transporter 2 (MCT2) is a major high-affinity pyruvate transporter encoded by the SLC16A7 gene, and is associated with glucose metabolism and cancer. Changes in the gut microbiota and host immune system are associated with many diseas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6b8ba78928e7946bf98803c9c0f077
https://doi.org/10.3390/ijms221910616
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9
Activation of the Integrated Stress Response and Metabolic Dysfunction in a Murine Model of Sleep Apnea
Autor: Zhuanhong Qiao, Ahamed A. Khalyfa, Brian Popko, David Gozal, Abdelnaby Khalyfa, Mahzad Akbarpour, Alex Gileles-Hillel
Publikováno v: American Journal of Respiratory Cell and Molecular Biology. 57:477-486
Intermittent hypoxia (IH) induces activation of the integrated stress response (ISR), but its role in IH-induced visceral white adipose tissue (vWAT) insulin resistance is unknown. CHOP is activated by chronic ISR, whereas GADD34 dephosphorylates the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817cc6a4668b151e54d25af1b842a21c
https://doi.org/10.1165/rcmb.2017-0057oc
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10
Integrated stress response activation by sleep fragmentation during late gestation in mice leads to emergence of adverse metabolic phenotype in offspring
Autor: Brian Popko, David Gozal, Abdelnaby Khalyfa, Wojciech Trzepizur, Zhuanhong Qiao
Publikováno v: Metabolism
Metabolism, Elsevier, 2017, 69, pp.188-198. ⟨10.1016/j.metabol.2017.01.026⟩
Background Late gestational sleep fragmentation (SF) is highly prevalent particularly in obese women, and induces metabolic dysfunction in adult offspring mice. SF induces activation of the integrated stress response (ISR), which might be involved in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb11b0374c422886c1dd17c5a29b4d32
https://doi.org/10.1016/j.metabol.2017.01.026
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