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pro vyhledávání: '"Zhuanglin Dai"'
Autor:
Jinfeng Cai, Hongbo Gao, Jiacong Zhao, Shujing Hu, Xinyu Liang, Yanyan Yang, Zhuanglin Dai, Zhongsi Hong, Kai Deng
Publikováno v:
eLife, Vol 10 (2021)
The major barrier to curing HIV-1 infection is a small pool of latently infected cells that harbor replication-competent viruses, which are widely considered the origin of viral rebound when antiretroviral therapy (ART) is interrupted. The difficulty
Externí odkaz:
https://doaj.org/article/a3e2700f3f6e47428d4f2a0befc0a43b
Autor:
Yanyan Yang, Hongbo Gao, Shujing Hu, Zhuanglin Dai, Jiacong Zhao, Xinyu Liang, Zhongsi Hong, Kai Deng, Jinfeng Cai
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
The major barrier to curing HIV-1 infection is a small pool of latently infected cells that harbor replication-competent viruses, which are widely considered the origin of viral rebound when antiretroviral therapy (ART) is interrupted. The difficulty
Autor:
Jiacong Zhao, Hongbo Gao, Dan Li, Wen Peng, Xi Chen, Wen Liu, Zhuanglin Dai, Kai Deng, Zhongsi Hong
Publikováno v:
Antimicrob Agents Chemother
Antiretroviral therapy (ART) suppresses HIV-1 replication but fails to cure the infection. The presence of an extremely stable viral latent reservoir, primarily in resting memory CD4(+) T cells, remains a major obstacle to viral eradication. The “s