Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Zhuanchang Wu"'
Autor:
Shuaiya Ma, Qi Wu, Wenxian Wu, Ye Tian, Jie Zhang, Chaojia Chen, Xue Sheng, Fangcheng Zhao, Lu Ding, Taixia Wang, Laixi Zhao, Yuying Xie, Yongxiang Wang, Xuetian Yue, Zhuanchang Wu, Jian Wei, Kun Zhang, Xiaohong Liang, Lifen Gao, Hongyan Wang, Guihua Wang, Chunyang Li, Chunhong Ma
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract According to the latest evidence, the microbial metabolite Urolithin A (UA), known for its role in promoting cellular health, modulates CD8+ T cell‐mediated antitumor activity. However, the direct target protein of UA and its underlying me
Externí odkaz:
https://doaj.org/article/657c653a712841f89996f5fb75da0840
Autor:
Yankun Zhang, Yuchen Fan, Huili Hu, Xiaohui Zhang, Zehua Wang, Zhuanchang Wu, Liyuan Wang, Xiangguo Yu, Xiaojia Song, Peng Xiang, Xiaodong Zhang, Tixiao Wang, Siyu Tan, Chunyang Li, Lifen Gao, Xiaohong Liang, Shuijie Li, Nailin Li, Xuetian Yue, Chunhong Ma
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Mitochondria dysfunction contributes to acute liver injuries, and mitochondrial regulators, such as PGC-1α and MCJ, affect liver regeneration. Therefore, identification of mitochondrial modulators may pave the way for developing therapeutic
Externí odkaz:
https://doaj.org/article/b9d2b1c9541949d3b5b30170360f89b2
Autor:
Lu Ding, Yang Sun, Yan Liang, Jie Zhang, Zhendong Fu, Caiyue Ren, Pengfei Li, Wen Liu, Rong Xiao, Hao Wang, Zhaoying Zhang, Xuetian Yue, Chunyang Li, Zhuanchang Wu, Yuemin Feng, Xiaohong Liang, Chunhong Ma, Lifen Gao
Publikováno v:
Advanced Science, Vol 11, Iss 16, Pp n/a-n/a (2024)
Abstract Inadequate β‐cell mass and insulin secretion are essential for the development of type 2 diabetes (T2D). TNF‐α‐induced protein 8‐like 1 (Tipe1) plays a crucial role in multiple diseases, however, a specific role in T2D pathogenesis
Externí odkaz:
https://doaj.org/article/4156cecc84ad4a0e8710791f05e9deea
Autor:
Deyan Jiao, Renhui Sun, Xiaolei Ren, Yingchun Wang, Panpan Tian, Yuzhen Wang, Detian Yuan, Xuetian Yue, Zhuanchang Wu, Chunyang Li, Lifen Gao, Chunhong Ma, Xiaohong Liang
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113632- (2024)
Externí odkaz:
https://doaj.org/article/5aef21538f57459298ffbfa6d2b41ff1
Autor:
Panpan Tian, Wenwen Yang, Xiaowei Guo, Tixiao Wang, Siyu Tan, Renhui Sun, Rong Xiao, Yuzhen Wang, Deyan Jiao, Yachen Xu, Yanfei Wei, Zhuanchang Wu, Chunyang Li, Lifen Gao, Chunhong Ma, Xiaohong Liang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Liver-resident natural killer cells develop locally and have multiple immunological roles in situ. Here the authors investigate the gut-liver axis and show the impact of the intestinal microbiota on the development of liver-resident natural killer ce
Externí odkaz:
https://doaj.org/article/db1710b6339d4a4d9456101338368e42
Autor:
Yuzhen Wang, Yingchun Wang, Wen Liu, Lu Ding, Xiaodi Zhang, Bo Wang, Zheng Tong, Xuetian Yue, Chunyang Li, Liyun Xu, Zhuanchang Wu, Xiaohong Liang, Chunhong Ma, Lifen Gao
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-13 (2023)
Abstract Mitochondrial function and homeostasis are critical to the proliferation of lung cancer cells. T-cell immunoglobulin and mucin domain-containing molecule 4 (TIM-4) promotes the development and progression of lung cancer. However, the role of
Externí odkaz:
https://doaj.org/article/57d55afae5c9412a8b67ef5af13b327e
Autor:
Zhuanchang Wu, Xiaobo Lei, Xin Wang, Zhaoying Zhang, Yuming Li, Lifen Gao, Xiaohong Liang, Peihui Wang, Jianwei Wang, Chunhong Ma
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/54ea8a78fd7d41e696baab95edc07f00
Autor:
Youzi Kong, Mengting Wu, Xiaoyu Wan, Min Sun, Yankun Zhang, Zhuanchang Wu, Chunyang Li, Xiaohong Liang, Lifen Gao, Chunhong Ma, Xuetian Yue
Publikováno v:
Redox Biology, Vol 63, Iss , Pp 102732- (2023)
Glutamine is critical for tumor progression, and restriction of its availability is emerging as a potential therapeutic strategy. The metabolic plasticity of tumor cells helps them adapting to glutamine restriction. However, the role of cholesterol m
Externí odkaz:
https://doaj.org/article/7a2caf9dfbc74aef8eb2a0b944e4a898
Autor:
Lu Ding, Yankun Zhang, Yingchun Wang, Yuzhen Wang, Zheng Tong, Pengfei Li, Chaojia Chen, Bo Wang, Xuetian Yue, Chunyang Li, Zhuanchang Wu, Xiaohong Liang, Chunhong Ma, Lifen Gao
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106871- (2023)
Summary: Emerging evidence shows that pancreatic β-cell function and quality are key determinants in the progression of type 2 diabetes (T2D). The transcription factor zinc finger homeobox 2 (Zhx2) is involved in proliferation and development of mul
Externí odkaz:
https://doaj.org/article/235d2415e529491e86f3972358e6caba
Autor:
Zhuanchang Wu, Liyuan Wang, Xin Wang, Yang Sun, Haoran Li, Zhaoying Zhang, Caiyue Ren, Xiaohui Zhang, Shuangjie Li, Jinghui Lu, Leiqi Xu, Xuetian Yue, Yue Hong, Qiang Li, Haizhen Zhu, Yaoqin Gong, Chengjiang Gao, Huili Hu, Lifen Gao, Xiaohong Liang, Chunhong Ma
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 14, Iss 6, Pp 1177-1198 (2022)
Background & Aims: Covalently closed circular DNA (cccDNA) of hepatitis B virus (HBV), existing as a stable minichromosome in the hepatocyte, is responsible for persistent HBV infection. Maintenance and sustained replication of cccDNA require its int
Externí odkaz:
https://doaj.org/article/e79761c168bf41d6ba1742a32b4442ef