Zobrazeno 1 - 10
of 386
pro vyhledávání: '"Zhuan, Zhou"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-19 (2024)
Abstract Background Studies have shown that oxidative stress and its resistance plays important roles in the process of tumor metastasis, and mitochondrial dysfunction caused by mitochondrial DNA (mtDNA) damage is an important molecular event in oxid
Externí odkaz:
https://doaj.org/article/e7a5f6ce72dd4891b4b6a8b2190fcd03
Autor:
Lidan Zeng, Yueming Zhu, Xin Cui, Junlong Chi, Amad Uddin, Zhuan Zhou, Xinxin Song, Mingji Dai, Massimo Cristofanilli, Kevin Kalinsky, Yong Wan
Publikováno v:
Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)
Abstract Tuning immune‐cold tumor hot has largely attracted attention to improve cancer treatment, including immunotherapy and antibody‐drug conjugates (ADCs). Utilizing multiomic analyses and experimental validation, this work identifies a pivot
Externí odkaz:
https://doaj.org/article/226b8baa18054f7db917c92399c165fc
Publikováno v:
The Innovation, Vol 4, Iss 6, Pp 100526- (2023)
Externí odkaz:
https://doaj.org/article/0be28c4ea9e04f049a3ca1e7a524b4b9
Autor:
Lun Wang, Min Gao, Qinglong Wang, Liyuan Sun, Muhammad Younus, Sixing Ma, Can Liu, Li Shi, Yang Lu, Bo Zhou, Suhua Sun, Guoqing Chen, Jie Li, Quanfeng Zhang, Feipeng Zhu, Changhe Wang, Zhuan Zhou
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
The prefrontal cortex is involved in cocaine abuse disorders. Here, the authors show that cocaine suppresses frontal association cortex (FrA) in awake mice and induces locomotor sensitization through a dopamine dependent VTA-vmPFC-FrA pathway.
Externí odkaz:
https://doaj.org/article/8f8856895d224ba09bfa7dd70b56a21c
A noncanonical function of EIF4E limits ALDH1B1 activity and increases susceptibility to ferroptosis
Autor:
Xin Chen, Jun Huang, Chunhua Yu, Jiao Liu, Wanli Gao, Jingbo Li, Xinxin Song, Zhuan Zhou, Changfeng Li, Yangchun Xie, Guido Kroemer, Jinbao Liu, Daolin Tang, Rui Kang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Ferroptosis is lipid peroxidation-dependent cell death that has potential to be harnessed as a cancer therapeutic. Here, the authors show that the translation initiation factor eIF4E can repress ALDH1B1 independent of translation, increasing lipid pe
Externí odkaz:
https://doaj.org/article/1437a6f736274efba756460f3064fbd5
Publikováno v:
The Journal of Engineering, Vol 2022, Iss 8, Pp 761-772 (2022)
Abstract The increasing complexity of interconnected power system has brought challenges to detailed dynamic simulation in terms of computational effort. Therefore, for transient stability assessment, dynamic equivalents of parts of large‐scale sys
Externí odkaz:
https://doaj.org/article/ca9c6d78e80f41bca6a1523c2cf98866
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
The covalent KRAS-G12C inhibitors (G12Ci) are rapidly changing the treatment landscape for advanced non-small cell lung cancer, but drug resistance remains a clinical challenge. Two recent studies have developed bispecific T cell engagers that form a
Externí odkaz:
https://doaj.org/article/37fde7de4e554d8ea6617fff671bc7bf
Publikováno v:
Energies, Vol 16, Iss 14, p 5374 (2023)
Hydrogen is receiving unprecedented momentum and is projected to meet a sizable share of the final energy demand in the future. The coupling between the hydrogen and power systems can help integrate volatile renewable energy, reduce curtailment, and
Externí odkaz:
https://doaj.org/article/481961afc0104fdd93c7900685dae95e
Autor:
San Xu, Zhuan Zhou, Xingzhi Peng, Xuxiu Tao, Peijun Zhou, Kun Zhang, Jinwu Peng, Dan Li, Liangfang Shen, Lifang Yang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-12 (2021)
Abstract Studies have indicated that dysfunction of autophagy is involved in the initiation and progression of multiple tumors and their chemoradiotherapy. Epstein–Barr virus (EBV) is a lymphotropic human gamma herpes virus that has been implicated
Externí odkaz:
https://doaj.org/article/ff25d756613542569f334ba8a9653a84
Autor:
Zhuan Zhou, Furong Huang, Indira Shrivastava, Rui Zhu, Aiping Luo, Michael Hottiger, Ivet Bahar, Zhihua Liu, Massimo Cristofanilli, Yong Wan
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 12, Pp 1-27 (2020)
Abstract KLF4 plays a critical role in determining cell fate responding to various stresses or oncogenic signaling. Here, we demonstrated that KLF4 is tightly regulated by poly(ADP‐ribosyl)ation (PARylation). We revealed the subcellular compartment
Externí odkaz:
https://doaj.org/article/687e65add3b54ce99a500eeaf7575523