Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Zhu-fang SHEN"'
Autor:
Yu Peng, Yi Huan, Jing-Jing Chen, Tian-Jiao Chen, Lei Lei, Jin-Ling Yang, Zhu-Fang Shen, Ting Gong, Ping Zhu
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionLimitation of pharmaceutical application of resveratrol (RSV) and piceatannol (PIC) continue to exist, there is a need to obtain the superior analogs of two stilbenes with promoted activity, stability, and bioavailability. Microbial trans
Externí odkaz:
https://doaj.org/article/7d25d151e7204e358e1369f8aa1905a7
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 11, Iss 1, Pp 1-10 (2019)
Abstract Background To investigate effects of metformin on the regulation of proteins of white adipose tissue (WAT) and brown adipose tissue (BAT) in obesity and explore the underlying mechanisms on energy metabolism. Methods C57BL/6J mice were fed w
Externí odkaz:
https://doaj.org/article/73806612d61549d8bd8ed484152bdd62
Autor:
Guo-liang Bai, Kai-li Hu, Yi Huan, Xing Wang, Lei Lei, Meng Zhang, Chun-yan Guo, Hong-sheng Chang, Li-bo Zhao, Jing Liu, Zhu-fang Shen, Xiao-ling Wang, Xin Ni
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
The purpose of this study was to explore the effect of the traditional Chinese medicine Fuyou formula on precocious puberty (PP). The Fy formula may exert an effect in female rats with PP and GT-7 cells through the GPR54/GnRH signaling pathway. To co
Externí odkaz:
https://doaj.org/article/b8128f6552584d00b101287c968b4a1b
Autor:
Yan-Min Chen, Chun-Fang Lian, Qian-Wen Sun, Ting-Ting Wang, Yuan-Yuan Liu, Jun Ye, Li-Li Gao, Yan-Fang Yang, Shuai-Nan Liu, Zhu-Fang Shen, Yu-Ling Liu
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 905 (2022)
Nonalcoholic fatty liver disease (NAFLD), obesity, and type 2 diabetes mellitus (T2DM) have highly related mechanisms. Ramulus Mori (Sangzhi) alkaloids (SZ-A) from Morus alba L. were approved in 2020 for the treatment of T2DM. In this study, we exami
Externí odkaz:
https://doaj.org/article/9b21542117364a6a9af2f8dc82134122
Publikováno v:
Guoji Yanke Zazhi, Vol 15, Iss 7, Pp 1151-1153 (2015)
AIM: To explore the primary culture conditions for four kinds of lens epithelial cells(LECs)of rat, rabbit, dog, and human, and measure their growth characteristics. METHODS: The lens capsule or anterior capsular tissue of rat, rabbit, dog and patien
Externí odkaz:
https://doaj.org/article/89db448065d8443c85682ba6f055458a
Autor:
Hui-peng Song, Kang Tian, Lei Lei, Zhu-fang Shen, Shou-xin Liu, Li-juan Zhang, Hong-rui Song, Xiao-feng Jin, Zhi-qiang Feng
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 1, Iss 3, Pp 166-171 (2011)
A series of novel N-(pyrimidin-4-yl)thiazol-2-amine derivatives have been synthesized and evaluated as glucokinase (GK) activators. Ethyl 2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl-amino)thiazole-5-carboxylate was found to be a po
Externí odkaz:
https://doaj.org/article/041b60cc84c042fba1f86dc3483ce748
Autor:
Lu Tie, Ying Xu, Yan-Hua Lin, Xiao-Hao Yao, Hong-Li Wu, Yu-Hua Li, Zhu-Fang Shen, He-Ming Yu, Xue-Jun Li
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 1, Pp 28-37 (2008)
Brain-pancreas relative protein (BPRP) is a novel protein that we found in our laboratory. Previously we demonstrated that it is involved in ischemia and depression. In light of the putative association between diabetes and clinical depression, and t
Externí odkaz:
https://doaj.org/article/ae17f056d3b04b7e87d510c9155e334f
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119350 (2015)
High-fat diet (HFD) leads to the development of obesity accompanied by insulin resistance, which increases the risk of type 2 diabetes mellitus and cardiovascular disease. Brown adipose tissue (BAT) plays an essential role in energy metabolism, thus
Externí odkaz:
https://doaj.org/article/65fc0c8c22394be696ddb94d4d3ee16a
Publikováno v:
PPAR Research, Vol 2014 (2014)
This study aimed to analyze the effects and potential mechanisms of pioglitazone on triglyceride and cholesterol metabolism in obese diabetic KKAy mice. Pioglitazone was orally administered to KKAy mice over 30 days. Compared to C57BL/6J mice, KKAy m
Externí odkaz:
https://doaj.org/article/a0d99b76318d4d708d08fd52263091eb
Autor:
Ling Qu, Xiao-chun Liang, Guo-qing Tian, Gai-li Zhang, Qun-li Wu, Xiu-mei Huang, Ya-zhong Cui, Yu-ling Liu, Zhu-fang Shen, Guo-qing Ma, Hao Lu, Yi Li, Hong Jiang, Xi-yan Yang, Guang-de Zhang, Chen-hua Yang
Publikováno v:
Chinese journal of integrative medicine. 28(4)
To assess the efficacy and safety of mulberry twig alkaloids (Sangzhi alkaloids, SZ-A) for treatment of type 2 diabetes in a randomized, double-blind, placebo-controlled multicenter clinical trial.A total of 200 patients were randomized to receive SZ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea03c4dee8048dd5ab2cf5edcf4a611
https://pubmed.ncbi.nlm.nih.gov/35048240
https://pubmed.ncbi.nlm.nih.gov/35048240