Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Zhu Pirot"'
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 548-558 (2021)
Gene therapy has entered a new era where numerous therapies for severe and rare diseases are generating robust and compelling clinical results. The rapid improvements in gene therapies over the past few years can be attributed to better scientific un
Externí odkaz:
https://doaj.org/article/58a5b658678d4506960027ca1ebc1bbf
Autor:
Claude Jourdan Le Saux, Philip Davy, Christopher Brampton, Seema S Ahuja, Steven Fauce, Pooja Shivshankar, Hieu Nguyen, Mahesh Ramaseshan, Robert Tressler, Zhu Pirot, Calvin B Harley, Richard Allsopp
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58423 (2013)
The emergence of diseases associated with telomere dysfunction, including AIDS, aplastic anemia and pulmonary fibrosis, has bolstered interest in telomerase activators. We report identification of a new small molecule activator, GRN510, with activity
Externí odkaz:
https://doaj.org/article/7f2715e00bc246fba8b2bbfea58687ec
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss, Pp 548-558 (2021)
Gene therapy has entered a new era where numerous therapies for severe and rare diseases are generating robust and compelling clinical results. The rapid improvements in gene therapies over the past few years can be attributed to better scientific un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4bbdda45c3b944d33b3f1b94a43f5cb
https://pubmed.ncbi.nlm.nih.gov/33997103
https://pubmed.ncbi.nlm.nih.gov/33997103
Publikováno v:
Cancer Research. 71:C15-C15
Telomeres are essential for maintenance of genomic stability. Short telomeres have been associated with genomic instability, and initiation and progression of human cancers. To protect their telomeres, up to 90% of human cancers activate telomerase.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::992fb4b0690faae2053bae6ab11fcebf
https://doi.org/10.1158/1538-7445.fbcr11-c15
https://doi.org/10.1158/1538-7445.fbcr11-c15