Zobrazeno 1 - 10
of 8 113
pro vyhledávání: '"Zhu Chen"'
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Objective Explore the therapeutic mechanism of Coptidis Rhizome (CR) in periodontitis using network pharmacology, and validate it through molecular docking and in vitro experiments. Methods Screened potential active components and target gen
Externí odkaz:
https://doaj.org/article/d38fca123939421ba793dd52fe3cbd6a
Autor:
Jie Xu, Bai-Yan Wang, Shan-He Yu, Shi-Jun Chen, Shuang-Shuang Yang, Rui Liu, Li-Juan Chen, Jian Hou, Zhu Chen, Wan-Hong Zhao, Ai-Li He, Jian-Qing Mi, Sai-Juan Chen
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-13 (2024)
Abstract Background The autologous anti–B-cell maturation antigen (BCMA) chimeric antigen receptor (CAR) T-cell therapy LCAR-B38M has been approved for the treatment of relapsed and refractory multiple myeloma in many countries across the world und
Externí odkaz:
https://doaj.org/article/bd5fe093d29e44bdad66104c6ea27c5c
Autor:
Changchun Hu, Shuo Li, Jie Zhou, Dan Wei, Xueying Liu, Zhu Chen, Hongquan Peng, Xun Liu, Yan Deng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The African swine fever virus (ASFV) has caused severe economic losses in the pig industry. To monitor ASFV spread, the p30 protein has been identified as an ideal infection marker due to its early and long-term expression during the ASFV in
Externí odkaz:
https://doaj.org/article/188a395270b9445c9ce9f052a1c62863
Autor:
Darja Andreev, Katerina Kachler, Mengdan Liu, Zhu Chen, Brenda Krishnacoumar, Mark Ringer, Silke Frey, Gerhard Krönke, David Voehringer, Georg Schett, Aline Bozec
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Eosinophils are involved in tissue homeostasis. Herein, we unveiled eosinophils as important regulators of bone homeostasis. Eosinophils are localized in proximity to bone-resorbing osteoclasts in the bone marrow. The absence of eosinophils
Externí odkaz:
https://doaj.org/article/5da2f219e2984371a8d14992bdd17d44
Autor:
Wen Jin, Yuting Dai, Li Chen, Honghu Zhu, Fangyi Dong, Hongming Zhu, Guoyu Meng, Junmin Li, Saijuan Chen, Zhu Chen, Hai Fang, Kankan Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Acute promyelocytic leukemia (APL) represents a paradigm for targeted differentiation therapy, with a minority of patients experiencing treatment failure and even early death. We here report a comprehensive single-cell analysis of 16 APL pat
Externí odkaz:
https://doaj.org/article/8faf8f577f5841a1af926a0e17e57d1f
Autor:
Wenxian Liu, Qi Wang, Yuguang Wang, Wenhao Zhan, Zhiqiang Wu, Hongbo Zhou, Haina Cheng, Zhu Chen
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 280, Iss , Pp 116588- (2024)
Simultaneous heterotrophic nitrification and aerobic denitrification (SND) is gaining tremendous attention due to its high efficiency and low cost in water treatment. However, SND on an industrial scale is still immature since effects of coexisting p
Externí odkaz:
https://doaj.org/article/b1b205e86479470cacab955ccf001a66
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Prolyl hydroxylase domain protein 2 (PHD2) is one of the intracellular oxygen sensors that mediates proteasomal degradation of hypoxia-inducible factor (HIF)-α via hydroxylation under normoxic conditions. Because of its canonical function in the hyp
Externí odkaz:
https://doaj.org/article/d2bf8a7f3d2f4971b7eced02f36c9154
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e31255- (2024)
Urinary tract infection (UTI) is one of the most common infectious diseases among children, but there is controversy regarding the use of preventive antibiotics for children first diagnosed with febrile pyelonephritis. To the best of our knowledge, n
Externí odkaz:
https://doaj.org/article/14ef7b53245246f691615f94a13985fa
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background The American Heart Association has developed a novel cardiovascular health indicator called Life’s Essential 8 (LE8). However, no one has reported using LE8 to assess periodontitis. This study aimed to investigate the associatio
Externí odkaz:
https://doaj.org/article/6d6fab91919443578b29190e11e6d3d1
Autor:
Shuangshuang Yang, Jie Xu, Yuting Dai, Shiwei Jin, Yan Sun, Jianfeng Li, Chenglin Liu, Xiaolin Ma, Zhu Chen, Lijuan Chen, Jian Hou, Jian-Qing Mi, Sai-Juan Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Cytokine release syndrome (CRS) is the most common complication of chimeric antigen receptor redirected T cells (CAR-T) therapy. CAR-T toxicity management has been greatly improved, but CRS remains a prime safety concern. Here we follow seru
Externí odkaz:
https://doaj.org/article/a407f060494947fd86f91f12ba36aefa