Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Zhu‐tao Wang"'
Autor:
Zhu‐tao Wang, Ruo‐yu Guan, Wei Gan, Zhang‐fu Yang, Bao‐ye Sun, Jing‐fang Wu, Dai Zhang, Guo‐qiang Sun, Xu‐kang Gao, Jin‐long Huang, Gao Liu, Cheng Zhou, Jian Zhou, Jia Fan, Yong Yi, Bo Hu, Shuang‐Jian Qiu
Publikováno v:
Cancer Medicine, Vol 13, Iss 23, Pp n/a-n/a (2024)
ABSTRACT Background and Aims The immune microenvironment (IME) plays a crucial role in the progression of hepatocellular carcinoma (HCC). In HCC, the IME is often compromised by hepatitis B virus (HBV) infection, chronic inflammation, and fibrosis. B
Externí odkaz:
https://doaj.org/article/29758f7b7ba446a18cd6235d48291ea7
Autor:
Bao-Ye Sun, Zhu-Tao Wang, Ke-Zhu Chen, Yang Song, Jing-Fang Wu, Dai Zhang, Guo-Qiang Sun, Jian Zhou, Jia Fan, Bo Hu, Yong Yi, Shuang-Jian Qiu
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Lymph node metastasis (LNM) facilitates distant tumor colonization and leads to the high mortality in patients with intrahepatic cholangiocarcinoma (ICC). However, it remains elusive how ICC cells subvert immune surveillance within the prima
Externí odkaz:
https://doaj.org/article/d15404389ca7490597ad2e74e888929d
Autor:
Bao-Ye Sun, Zhang-Fu Yang, Zhu-Tao Wang, Gao Liu, Cheng Zhou, Jian Zhou, Jia Fan, Wei Gan, Yong Yi, Shuang-Jian Qiu
Publikováno v:
World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background CD73 promotes progression in several malignancies and is considered as a novel immune checkpoint. However, the function of CD73 in intrahepatic cholangiocarcinoma (ICC) remains uncertain. In this study, we aim to investigate the r
Externí odkaz:
https://doaj.org/article/a2269dc43b3847e68049b1b8e6e359b4
Autor:
Bao-Ye Sun, Pei-Yi Gu, Ruo-Yu Guan, Cheng Zhou, Jian-Wei Lu, Zhang-Fu Yang, Chao Pan, Pei-Yun Zhou, Ya-Ping Zhu, Jia-Rui Li, Zhu-Tao Wang, Shan-Shan Gao, Wei Gan, Yong Yi, Ye Luo, Shuang-Jian Qiu
Publikováno v:
World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background Preoperative prediction of microvascular invasion (MVI) is critical for treatment strategy making in patients with hepatocellular carcinoma (HCC). We aimed to develop a deep learning (DL) model based on preoperative dynamic contra
Externí odkaz:
https://doaj.org/article/ce22ab6ca8394d6da70330f907ccbe6d
Autor:
Gao Liu, Jian Sun, Zhang-Fu Yang, Cheng Zhou, Pei-Yun Zhou, Ruo-Yu Guan, Bao-Ye Sun, Zhu-Tao Wang, Jian Zhou, Jia Fan, Shuang-Jian Qiu, Yong Yi
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-19 (2021)
Abstract Cancer-associated fibroblasts (CAFs) are commonly acquired activated extracellular matrix (ECM)-producing myofibroblasts, a phenotypes with multiple roles in hepatic fibrogenesis and carcinogenesis via crosstalk with cohabitating stromal/can
Externí odkaz:
https://doaj.org/article/672cada69bfa4dc6aea47f0c86c60221
Autor:
Bao-Ye Sun, Cheng Zhou, Ruo-Yu Guan, Gao Liu, Zhang-Fu Yang, Zhu-Tao Wang, Wei Gan, Jian Zhou, Jia Fan, Yong Yi, Shuang-Jian Qiu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
PurposeTo dissect the tumor ecosystem following immune checkpoint blockades (ICBs) in intrahepatic cholangiocarcinoma (ICC) at a single-cell level.MethodsSingle-cell RNA sequencing (scRNA-seq) data of 10 ICC patients for the ICB clinical trial were e
Externí odkaz:
https://doaj.org/article/d23645731d5e411dbefe13360590565c
Publikováno v:
Applied Sciences; Volume 13; Issue 13; Pages: 7834
To investigate the impact of crack inclination angle on the tensile strength and characteristics of splitting failure in rock, split tests were conducted on fine-grained sandstone with pre-existing cracks under different crack inclination angle condi
Autor:
Shuang-Jian Qiu, Ruo-Yu Guan, Jian Sun, Cheng Zhou, Jia Fan, Bao-Ye Sun, Gao Liu, Jian Zhou, Zhu-Tao Wang, Pei-Yun Zhou, Zhang-Fu Yang, Yong Yi
Publikováno v:
Digestive and Liver Disease. 54:692-700
Background Brahma-related gene 1 (BRG1) is essential for embryogenesis and cellular metabolism. A deficiency of BRG1 in vivo decreases lipid droplets, but the molecular mechanism underlying its role in lipid metabolism associated with hepatocellular
Autor:
Gao Liu, Zhang-Fu Yang, Jian Sun, Bao-Ye Sun, Pei-Yun Zhou, Cheng Zhou, Ruo-Yu Guan, Zhu-Tao Wang, Yong Yi, Shuang-Jian Qiu
Publikováno v:
Cellular oncology (Dordrecht).
Background CXCL11 has been reported to be up-regulated in hepatocellular carcinoma (HCC) tissues and cancer-associated fibroblasts (CAFs), and CAF-secreted CXCL11 has been found to promote HCC cell proliferation and migration. Knowledge on how CAFs p
Autor:
Jian Sun, Zhang-Fu Yang, Shuang-Jian Qiu, Yong Yi, Cheng Zhou, Ruo-Yu Guan, Gao Liu, Bao-Ye Sun, Pei-Yun Zhou, Jian Zhou, Jia Fan, Zhu-Tao Wang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-19 (2021)
Cell Death & Disease
Cell Death & Disease
Cancer-associated fibroblasts (CAFs) are commonly acquired activated extracellular matrix (ECM)-producing myofibroblasts, a phenotypes with multiple roles in hepatic fibrogenesis and carcinogenesis via crosstalk with cohabitating stromal/cancer cells