Marein, a novel natural product for restoring chemo-sensitivity to cancer cells through competitive inhibition of ABCG2 function

Autor: Li, Yixuan, Guo, Fanfan, Wang, Wenjing, Lv, FangLin, Zhang, Lu, Zhu, Mingxian, Yang, Shumin, Dong, Shunli, Zhou, Mingxuan, Li, Zhenyun, Zhu, Zengyan, Yang, Jin-Ming, Zhang, Yi

Publikováno v: In Biochemical Pharmacology October 2024 228

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Targeting of tumoral NAC1 mitigates myeloid-derived suppressor cell-mediated immunosuppression and potentiates anti-PD-1 therapy in ovarian cancer.

Autor: Dong S; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University; Jiangsu, China, suzhou, China., Ye C; Center of Translational Medicine, First People's Hospital of Taicang City, Taicang Affiliated Hospital of Soochow University; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China, China., Li B; Department of Hepatopancreatobiliary Surgery, Suzhou Ninth Hospital Affiliated to Soochow University, Soochow University, Suzhou, Jiangsu, China, Suzhou, Jiangsu, China., Lv F; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University; Jiangsu, China;, Soochow, China., Zhang L; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University; Jiangsu, China;, Jiangsu, China;, China., Yang S; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University; Jiangsu, China;, Jiangsu, China;, China., Wang F; Department of Gynecology and obstetrics, First Affiliated Hospital, Soochow University, China, China., Zhu M; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University; Jiangsu, China;, suzhou, China., Zhou M; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University; Jiangsu, China;, Soochow, China., Guo F; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University; Jiangsu, China;, Soochow，Jiangsu, China;, China., Li Z; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University; Jiangsu, China;, Soochow, China., Peng L; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University; Jiangsu, China;, Soochow, China., Ji C; University of Southern California, Los Angeles, CA, United States., Lu X; Department of Pathology, Suzhou Ninth Hospital Affiliated to Soochow University, Soochow University, Suzhou, Jiangsu, China, China., Cheng Y; Center of Translational Medicine, First People's Hospital of Taicang City, Taicang Affiliated Hospital of Soochow University; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu, China, China., Ren X; University of Kentucky, College of Medicine, United States., Chen Y; First Affiliated Hospital of Soochow University, Suzhou, China., Zhou J; Department of Gynecology and obstetrics, First Affiliated Hospital, Soochow University, China, China., Yang J; University of Kentucky, Lexington, United States., Zhang Y; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University; Jiangsu, China, suzhou, China.

Publikováno v: Cancer immunology research [Cancer Immunol Res] 2024 Nov 12. Date of Electronic Publication: 2024 Nov 12.