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DYRK1A antagonists rescue degeneration and behavioural deficits of in vivo models based on amyloid-β, Tau and DYRK1A neurotoxicity.

Autor: Zhu, Bangfu¹ (AUTHOR), Parsons, Tom¹ (AUTHOR), Foley, Christopher² (AUTHOR), Shaw, Yeng³ (AUTHOR), Dunckley, Travis⁴ (AUTHOR), Hulme, Christopher^2,3 (AUTHOR), Hodge, James J. L.¹ (AUTHOR) james.hodge@bristol.ac.uk

Publikováno v: Scientific Reports. 9/23/2022, Vol. 12 Issue 1, p1-14. 14p.

Electric signals regulate directional migration of ventral midbrain derived dopaminergic neural progenitor cells via Wnt/GSK3β signaling

Autor: Liu, Jia, Zhu, Bangfu, Zhang, Gaofeng, Wang, Jian, Tian, Weiming, Ju, Gong, Wei, Xiaoqing, Song, Bing

Publikováno v: In Experimental Neurology January 2015 263:113-121

DYRK1a Inhibitor Mediated Rescue of Drosophila Models of Alzheimer’s Disease-Down Syndrome Phenotypes

Autor: Zhu, Bangfu, Parsons, Tom A, Stensen, Wenche, Mjøen Svendsen, John S, Fugelli, Anders, Hodge, James J L

Publikováno v: Zhu, B, Parsons, T A, Stensen, W, Mjøen Svendsen, J S, Fugelli, A & Hodge, J J L 2022, ' DYRK1a inhibitor mediated rescue of Drosophila models of Alzheimer’s disease-Down Syndrome phenotypes ', Frontiers in Pharmacology, vol. 13, 881385 . https://doi.org/10.3389/fphar.2022.881385

Alzheimer’s disease (AD) is the most common neurodegenerative disease which is becoming increasingly prevalent due to ageing populations resulting in huge social, economic, and health costs to the community. Despite the pathological processing of g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2fe4e1bd0be601c5d280db3add76d49
https://hdl.handle.net/10037/26607

Hereditary spastic paraparesis presenting as cerebral palsy due to ADD3 variant with mechanistic insight provided by a Drosophila γ‐adducin model.

Autor: Sanchez Marco, Silvia Beatriz, Buhl, Edgar, Firth, Rose, Zhu, Bangfu, Gainsborough, Mary, Beleza‐Meireles, Ana, Moore, Sandra, Caswell, Richard, Stals, Karen, Ellard, Sian, Kennedy, Cameron, Hodge, James J. L., Majumdar, Anirban

Publikováno v: Clinical Genetics; Dec2022, Vol. 102 Issue 6, p494-502, 9p