Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Zhouqing Luo"'
Autor:
Li Cheng, Shijun Zhao, Tianyi Li, Sha Hou, Zhouqing Luo, Jinsheng Xu, Wenfei Yu, Shuangying Jiang, Marco Monti, Daniel Schindler, Weimin Zhang, Chunhui Hou, Yingxin Ma, Yizhi Cai, Jef D. Boeke, Junbiao Dai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution (SCRaMbLE) is a promising tool to study genomic rearrangements. However, the potential of SCRaMbLE to study genomic rearrangements is currently hindered, because
Externí odkaz:
https://doaj.org/article/55e225a83ac445e9b633a57718802700
Autor:
Shuangying Jiang, Zhouqing Luo, Jie Wu, Kang Yu, Shijun Zhao, Zelin Cai, Wenfei Yu, Hui Wang, Li Cheng, Zhenzhen Liang, Hui Gao, Marco Monti, Daniel Schindler, Linsen Huang, Cheng Zeng, Weimin Zhang, Chun Zhou, Yuanwei Tang, Tianyi Li, Yingxin Ma, Yizhi Cai, Jef D. Boeke, Qiao Zhao, Junbiao Dai
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The genome of an organism is inherited from its ancestor and continues to evolve over time, however, the extent to which the current version could be altered remains unknown. To probe the genome plasticity of Saccharomyces cerevisiae, here w
Externí odkaz:
https://doaj.org/article/67379eb1b6774156b55209210e2946e4
Autor:
Zhenzhen Liang, Zhouqing Luo, Weimin Zhang, Kang Yu, Hui Wang, Binan Geng, Qing Yang, Zuoyu Ni, Cheng Zeng, Yihui Zheng, Chunyuan Li, Shihui Yang, Yingxin Ma, Junbiao Dai
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104982- (2022)
Summary: The relationship between gene sequence and function matters for fundamental and practical reasons. Here, yeast essential genes were systematically refactored to identify invariable sequences in the coding and regulatory regions. The coding s
Externí odkaz:
https://doaj.org/article/5a95956e6a0840d59ad716a9f74f22b0
Autor:
Zhouqing Luo, Kang Yu, Shangqian Xie, Marco Monti, Daniel Schindler, Yuan Fang, Shijun Zhao, Zhenzhen Liang, Shuangying Jiang, Meiwei Luan, Chuanle Xiao, Yizhi Cai, Junbiao Dai
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-18 (2021)
Abstract Background Redundancy is a common feature of genomes, presumably to ensure robust growth under different and changing conditions. Genome compaction, removing sequences nonessential for given conditions, provides a novel way to understand the
Externí odkaz:
https://doaj.org/article/9029318b4f7644d6b58af1b2969643f8
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-4 (2020)
Externí odkaz:
https://doaj.org/article/ef5500e60f7647d494a93209fc621cca
Autor:
Zhouqing Luo, Lihui Wang, Yun Wang, Weimin Zhang, Yakun Guo, Yue Shen, Linghuo Jiang, Qingyu Wu, Chong Zhang, Yizhi Cai, Junbiao Dai
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The use of synthetic chromosomes and the recombinase-based SCRaMbLE system could enable rapid strain evolution through massive chromosome rearrangements. Here the authors present ReSCuES, which uses auxotrophic markers to rapidly identify yeast with
Externí odkaz:
https://doaj.org/article/a9907f577d24483dabdd7564338c8e60
Autor:
Wei Liu, Zhouqing Luo, Yun Wang, Nhan T. Pham, Laura Tuck, Irene Pérez-Pi, Longying Liu, Yue Shen, Chris French, Manfred Auer, Jon Marles-Wright, Junbiao Dai, Yizhi Cai
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Pathway optimization and chassis engineering are usually carried out in a step-wise and trial-and-error manner. Here the authors present ’SCRaMbLE-in’ that combines in-vitro pathway rapid prototyping with in-vivo genome integration and optimizati
Externí odkaz:
https://doaj.org/article/ad81529cd72f4cf5b421bbb08fbc1ca6
Autor:
Tianyi Li, Shijun Zhao, Li Cheng, Sha Hou, Zhouqing Luo, Jinsheng Xu, Wenfei Yu, Shuangying Jiang, Marco Monti, Daniel Schindler, Weimin Zhang, Chunhui Hou, Yingxin Ma, Yizhi Cai, Jef D. Boeke, Junbiao Dai
SummaryGenomic rearrangements contribute to gene copy number alterations, disruption of protein-coding sequences and/or perturbation of cis-regulatory networks. SCRaMbLE, a Cre/loxP-based system implanted in synthetic yeast chromosomes, can effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53fdfc80018dc80c3275879d5b359448
https://doi.org/10.1101/2023.05.21.541650
https://doi.org/10.1101/2023.05.21.541650
Autor:
Shuangying Jiang, Zhouqing Luo, Kang Yu, Shijun Zhao, Zelin Cai, Wenfei Yu, Hui Wang, Li Cheng, Zhenzhen Liang, Hui Gao, Marco Monti, Daniel Schindler, Linsen Huang, Cheng Zeng, Weimin Zhang, Chun Zhou, Yuanwei Tang, Tianyi Li, Yingxin Ma, Yizhi Cai, Jef D. Boeke, Junbiao Dai
SUMMARYThe genome of an organism is inherited from its ancestor and keeps evolving over time, however, how much the current version could be altered remains unknown. Here, we use the left arm of chromosome XII (chrXIIL) as an example to probe the gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27a38e4a2db860b1cbaa909c24831529
https://doi.org/10.1101/2022.10.04.509869
https://doi.org/10.1101/2022.10.04.509869
Autor:
Yue Shen, Feng Gao, Yun Wang, Yuerong Wang, Ju Zheng, Jianhui Gong, Jintao Zhang, Zhouqing Luo, Daniel Schindler, Yang Deng, Weichao Ding, Tao Lin, Reem Swidah, Hongcui Zhao, Shuangying Jiang, Cheng Zeng, Shihong Chen, Tai Chen, Yong Wang, Yisha Luo, Leslie Mitchell, Joel S. Bader, Guojie Zhang, Xia Shen, Jian Wang, Xian Fu, Junbiao Dai, Jef D. Boeke, Huanming Yang, Xun Xu, Yizhi Cai
Aneuploidy compromises genomic stability, often leading to embryo inviability, and is frequently associated with tumorigenesis and aging. Different aneuploid chromosome stoichiometries lead to distinct transcriptomic and phenotypic changes, making it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5000a0ef5fbf80958ea1279f65fa3860
https://doi.org/10.1101/2022.09.01.506252
https://doi.org/10.1101/2022.09.01.506252