Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Zhoudong Zhang"'
Autor:
Mengmeng Wang, Zhoudong Zhang, Mengxi Chen, Yixin Lv, Sheng Tian, Fanyi Meng, Yawen Zhang, Xuqin Guo, Yinshuang Chen, Man Yang, Jiawei Li, Tian Qiu, Fang Xu, Zhi Li, Qi Zhang, Jie Yang, Jing Sun, Hongjian Zhang, Haiyang Zhang, Huanqiu Li, Weipeng Wang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 8, Pp 1-13 (2023)
Abstract Metastatic colorectal cancer (mCRC) is a major cause of cancer-related mortality due to the absence of effective therapeutics. Thus, it is urgent to discover new drugs for mCRC. Fucosyltransferase 8 (FUT8) is a potential therapeutic target w
Externí odkaz:
https://doaj.org/article/7a9c042799264e70a9230d15a9ae936a
Autor:
Yifan Zhu, Mengze Zhou, Xiangyu Cheng, Hui Wang, Yehong Li, Yueyue Guo, Yaxuan Wang, Sheng Tian, Tianqi Mao, Zhoudong Zhang, Duxin Li, Qinghua Hu, Huanqiu Li
Publikováno v:
Journal of Medicinal Chemistry. 66:6315-6332
Publikováno v:
Drug Discovery Today. 28:103484
Therapeutic potential of fucosyltransferases in cancer and recent development of targeted inhibitors
Publikováno v:
Drug Discovery Today. 28:103394
Fucosyltransferases (FUTs) have significant roles in various pathophysiological events. Their high expression is a signature of malignant cell transformation, contributing to many abnormal events during cancer development, such as uncontrolled cell p