Genomewide Association Study Identifies Novel Genetic Loci That Modify Antiplatelet Effects and Pharmacokinetics of Clopidogrel

Autor: Xin-Xin Li, Li Hp, Hong Wu, Liping Mai, Lei Hp, Zhang B, Zhang Zw, Shuwen Liu, Zhong Wp, Sun S, Wang Xp, Zhou Hk, Guo-Dong He, Zhong Sl, Lan Tang, Chen Jy, Ma Dl, Haotian Lin

Publikováno v: Clinical Pharmacology and Therapeutics

Genetic variants in the pharmacokinetic (PK) mechanism are the main underlying factors affecting the antiplatelet response to clopidogrel. Using a genomewide association study (GWAS) to identify new genetic loci that modify antiplatelet effects in Ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e370431304165236407437db1a76aca
https://pubmed.ncbi.nlm.nih.gov/27981573

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Salvage Surgery for Initially Unresectable HCC With PVTT Converted by Locoregional Treatment Plus Tyrosine Kinase Inhibitor and Anti-PD-1 Antibody.

Autor: Wang L; Department of Hepatic Surgery VI, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, People's Republic of China., Feng JK; Department of Hepatic Surgery VI, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, People's Republic of China., Lu CD; Department of Hepatic Surgery VI, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, People's Republic of China., Wu JY; Department of Hepatobiliary and Pancreatic Surgery, Fujian Provincial Hospital of Fujian Medical University, Fuzhou, People's Republic of China., Zhou B; Department of Hepatic Surgery VI, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, People's Republic of China., Wang K; Department of Hepatic Surgery VI, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, People's Republic of China., Wei XB; Department of Hepatic Surgery VI, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, People's Republic of China., Liang C; Department of Hepatobiliary Surgery, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China., Zhou HK; Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jiaxing, Affiliated Hospital of Jiaxing University, Jiaxing, People's Republic of China., Shi J; Department of Hepatic Surgery VI, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, People's Republic of China., Guo WX; Department of Hepatic Surgery VI, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, People's Republic of China., Lau WY; Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, People's Republic of China., Yan ML; Department of Hepatobiliary and Pancreatic Surgery, Fujian Provincial Hospital of Fujian Medical University, Fuzhou, People's Republic of China., Cheng SQ; Department of Hepatic Surgery VI, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, People's Republic of China.

Publikováno v: The oncologist [Oncologist] 2024 Aug 05; Vol. 29 (8), pp. e1041-e1050.