Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Zhou DC"'
Publikováno v:
Leukemia. 11:1516-1522
The drug GG918 has been specifically developed for overcoming MDR phenotype and is now in use in clinical trials. In this study, the effects of GG918 on leukemic cell were investigated using a 3 day MTT assay. Results showed that, in a highly resista
Publikováno v:
International Journal of Cancer. 65:365-371
To investigate the mechanism of resistance to an antineoplastic natural product homoharringtonine (HHT) in leukemic cells, we have established 5 sub-lines of human myeloid leukemia K562 cells, designated as K-H30, K-H100, K-H200, K-H300 and K-H400, w
Autor:
Jean-Pierre Marie, Anne-Marie Faussat, Zhou Dc, Loan Hoang-Ngoc, Robert Zittoun, Alain Delmer, Domenico Russo
Publikováno v:
Leukemia & Lymphoma. 13:27-30
To evaluate the frequency and the prognostic value of different mechanisms of drug resistance in acute leukemias, we investigated the expression of mdr1 by immunocytochemistry, mRNA slot blot or RT-PCR in 182 cases of adult acute myeloid and 37 cases
Autor:
Olivier Legrand, Robert Zittoun, Anne-Marie Suberville, Domenico Russo, Zhou Dc, Jean-Pierre Marie
Publikováno v:
Leukemia & Lymphoma. 8:261-265
Sequential evaluation of P-glycoprotein expression was performed in 29 patients with acute nonlymphoblastic leukemia using immunocytochemistry with the C219 antibody. At diagnosis, 32% of the patients exhibited more than 5% of the P-gp(+) leukemic ce
Autor:
Vinod Raina, Zhou Dc, Sudha Sazawal, Jean-Pierre Marie, Sandeep Gurbuxani, Manorama Bhargava, Laxman Singh Arya, Ghislaine Simonin
Publikováno v:
Annals of hematology. 76(5)
In order to investigate the phenomenon of multidrug resistance as a possible mechanism for poor response to treatment in patients with acute lymphoblastic leukemia (ALL) from India, a series of 32 cases of de novo untreated ALLs were analyzed by a cD
Autor:
Vincent Levy, Alain Delmer, Sylvie Ramond, M. Cadiou, Zhou Dc, Jean-Pierre Marie, Mathilde Hunault, Zittoun R, Jean-Yves Perrot, Bernard Rio, Franck Viguié, Florence Cymbalista
Publikováno v:
Annals of hematology. 74(2)
The clinical significance of the multidrug resistance (MDR 1) gene phenotype was investigated in newly diagnosed AML and was compared with other clinical and biological prognostic factors in patients who received at least one course of induction ther
Publikováno v:
European journal of cancer (Oxford, England : 1990). (6)
Autor:
Zhou Dc, Jean-Pierre Marie, Mariagrazia Michieli, Angela Michelutti, Michele Baccarani, R Fanin, Faussat Am, Daniela Damiani, R. Zittoun, Domenico Russo, C. Melli
Publikováno v:
Leukemialymphoma. 15(5-6)
By using RNA slot-blot technique, the frequency and the degree of GST pi and mdr-1 gene coexpression were investigated in 23 AML patients, 9 ALL, 9 CLL and 11 cases of NHL in an attempt to study their clinical and prognostic relevance. GST pi and mdr