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Publikováno v:
Experimental Biology and Medicine. 242:961-973
Acylation-stimulating protein (ASP), produced through activation of the alternative complement immune system, modulates lipid metabolism. Using a trans-well co-culture cell model, the mitigating role of α7-nicotinic acetylcholine receptor (α7nAChR)
Autor:
ZHOU-YANG JIAO1, JING WU2 wu2006jing@163.com, CHAO LIU1, BING WEN1, WEN-ZENG ZHAO1, XIN-LING DU3
Publikováno v:
Molecular Medicine Reports. Oct2016, Vol. 14 Issue 4, p2959-2966. 8p.
Publikováno v:
Molecular Medicine Reports
Obesity is associated with chronic low‑grade inflammation, which is characterized by increased infiltration of macrophages into adipose tissue. Acylation stimulating protein (ASP) is an adipokine derived from the immune complement system, which con
Autor:
HuiLing Lu, Jing Wu, Zhe Zhang, Zhou-yang Jiao, Katherine Cianflone, Zhi-hui Tang, Hao-hao Zhang
Publikováno v:
Biochemistry and Cell Biology. 93:335-342
Inflammation is a key feature in adipose tissue, especially in association with obesity comorbidies. The novel adipokine acylation stimulating protein (ASP) is one factor implicated in the inflammatory response. The disruption of the α7 nicotine ace
Publikováno v:
BMB Reports
The main purpose of this study was to investigate whether type 3 muscarinic acetylcholine receptor (M3R) dysfunction induced vascular hyperpermeability. Transwell system analysis showed that M3R inhibition by selective antagonist 4-diphenylacetoxy-N-
Publikováno v:
Journal of Cellular Biochemistry. 112:1622-1629
The novel adipokine acylation stimulating protein (ASP) is involved in lipid metabolism and obesity-related disorders. Adipophilin and perilipin, two members of the lipid droplet protein family, participate not only in fat storage within adipocytes,
Publikováno v:
Biochemistry and cell biology = Biochimie et biologie cellulaire. 92(2)
The objective was to investigate whether M3 muscarinic acetylcholine receptor (mAChR) dysfunction disrupts the linkage between the vascular endothelial (VE)-cadherin in the adherens junctional complex and the actin-based cytoskeleton, increasing vasc