Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Zhongzhen, Zhou"'
Autor:
Bingtian Xu, Yunyun Qin, Dan Li, Ningbo Cai, Jinling Wu, Lan Jiang, Limei Jie, Zhongzhen Zhou, Jiangping Xu, Haitao Wang
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Inhibition of phosphodiesterase 4 (PDE4) produces neuroprotective effects against cerebral ischemia. However, the involved mechanism remains unclear. Augmentation of endoplasmic reticulum (ER) stress promotes neuronal apoptosis, and excessive oxidati
Externí odkaz:
https://doaj.org/article/0131b13cd3de46e9a9c200b55b51e28e
Autor:
Jiahong Zhong, Hui Yu, Chang Huang, Qiuping Zhong, Yaping Chen, Jinfeng Xie, Zhongzhen Zhou, Jiangping Xu, Haitao Wang
Publikováno v:
Redox Biology, Vol 16, Iss , Pp 47-58 (2018)
Phosphodiesterase 4 (PDE4) is a promising target for the treatment of Parkinson's disease (PD). However, the underlying mechanism has not yet been well elucidated. Additionally, most of current PDE4 inhibitors produce severe nausea and vomiting respo
Externí odkaz:
https://doaj.org/article/cc5aafc7054c490192a9d83a47d07404
Publikováno v:
Chemical Communications. 58:3342-3345
A Cu/TEMPO-catalyzed tandem multiple oxidative dehydrogenation and cycloaddition has been developed, which affords 4-acyl-1,2,3-triazoles and 4-diketo-1,2,3-triazoles from readily-available aryl-alkyl ketones (or alcohols) and different organic azide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9b05eaa306887ceef0b4aa3661dbd6
https://doi.org/10.1039/d1cc06477k
https://doi.org/10.1039/d1cc06477k
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 8, Pp o2015-o2015 (2009)
In the crystal structure of the title compound, C25H30N2O4, the steric size of the tert-butyl group causes the 3,5-dimethylphenyl ring to adopt a transoid geometry with respect to the N—C(O) bond. The six-membered heterocyclic ring is disordered ov
Externí odkaz:
https://doaj.org/article/a2944e8e7dfb4659bfba309e7c1e34d2
Autor:
Jiahong, Zhong, Jinfeng, Xie, Jiao, Xiao, Dan, Li, Bingtian, Xu, Xinyi, Wang, Huizhen, Wen, Zhongzhen, Zhou, Yufang, Cheng, Jiangping, Xu, Haitao, Wang
Publikováno v:
Free radical biologymedicine. 135
The etiology of Parkinson's disease (PD) is generally not well understood, but it is believed to involve excessive oxidative insult. Hence, identifying therapeutic targets and compounds that exhibit protective effects against oxidative damage is a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8927a13e46eef9677c0081aa7c51675
https://pubmed.ncbi.nlm.nih.gov/30818055
https://pubmed.ncbi.nlm.nih.gov/30818055
Publikováno v:
The Journal of organic chemistry. 82(17)
A copper-catalyzed three-component reaction of methyl ketones, organic azides, and various one-carbon (C1) donors was developed that provides 4-acyl-1,2,3-triazoles in moderate to good yields. While DMF, DMA, TMEDA, or DMSO can serve as the C1 donor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc36bb7566dc0ad5075f6de045838e21
https://pubmed.ncbi.nlm.nih.gov/28749668
https://pubmed.ncbi.nlm.nih.gov/28749668
Publikováno v:
Acta Crystallographica Section E Structure Reports Online. 61:o3738-o3740
In the crystal structure of the title compound, C21H19ClN2O4·0.65H2O, the dihedral angle formed by the bicyclic benzopyran system and the chlorobenzene ring is 55.1 (2)°. In the crystal structure, molecules are linked into molecular tapes thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a000e2cf5c634b38f7d524f6471f162f
https://doi.org/10.1107/s1600536805033118
https://doi.org/10.1107/s1600536805033118
Publikováno v:
Acta Crystallographica Section E Structure Reports Online. 61:o2510-o2512
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bd5aeef56ffcb258a11187bc34a1185
https://doi.org/10.1107/s1600536805021938
https://doi.org/10.1107/s1600536805021938
Publikováno v:
Acta Crystallographica Section E Structure Reports Online. 61:o1273-o1275
In the title compound, C11H10Cl2O3, the six-membered heterocyclic ring adopts a half-chair conformation. An intermolecular C—H⋯O hydrogen bond and π–π stacking are observed in the crystal structure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e11e319f313b4b2b170f6210617dbf63
https://doi.org/10.1107/s1600536805010421
https://doi.org/10.1107/s1600536805010421
Autor:
Wei Huang1, Zhongzhen Zhou1, Peiliang Zhao1, Qiong Chen1, Deyou Teng1, Guangfu Yang1 gfyang@mail.ccnu.edu.cn
Publikováno v:
Acta Crystallographica: Section E. May2005, Vol. 61 Issue 5, po1273-o1275. 3p.