Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Zhongzhao Wang"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-6 (2024)
Abstract A 40-year-old male with EML4-ALK (E6:A20) fusion variant 3 and previously unreported PLEKHA7-ALK (P3:A20) fusion in lung adenocarcinoma exhibited resistance to alectinib and chemotherapy. Subsequent next-generation sequencing (NGS) from the
Externí odkaz:
https://doaj.org/article/574008b1f2334b3f99ae4d37449cd8f5
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-17 (2024)
Abstract Background Cisplatin (DDP) chemotherapy is commonly used in therapy for non-small cell lung cancer (NSCLC), but increased drug resistance has become a huge obstacle. Baicalin (BA) contributed to the sensitivity of NSCLC to DDP. Here, we aime
Externí odkaz:
https://doaj.org/article/cabf573c636f4b19827cfccadefe3ed8
Autor:
Peikai Ding, Shengbin Pei, Zheng Qu, Yazhe Yang, Qiang Liu, Xiangyi Kong, Zhongzhao Wang, Jing Wang, Yi Fang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundTriple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer lacking hormone receptors and HER2 expression, leading to limited treatment options and poor prognosis. Mitophagy, a selective autophagy process targeting damage
Externí odkaz:
https://doaj.org/article/edc5c48475e64c509df428c082d44479
Autor:
Qiang Liu, Zheng Qu, Hao Dong, Yihang Qi, Juan Wu, Wenxiang Zhang, Xiangyu Wang, Zhongzhao Wang, Yi Fang, Jing Wang
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Large cohort studies examining trends in cancer-related suicide are lacking. We analyzed data from the Surveillance, Epidemiology, and End Results (SEER) database, encompassing a total of 4,870,410 patients diagnosed with cancer from 1975 to
Externí odkaz:
https://doaj.org/article/92b8c9e8e38841e5b84b03f948f739b4
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
PurposeIt is still unclear whether KEAP1 mutation is detrimental to immunotherapy of lung adenocarcinoma (LUAD) patients, we try to analyse the exact changes in the TME in LUAD patients with KEAP1 mutations and to identify key factors influencing pro
Externí odkaz:
https://doaj.org/article/93b30e41d6ac46818aa40e9d207feee9
Autor:
Qiang Liu, Wenxiang Zhang, Qi Li, Li Chen, Xiangyu Wang, Zhongzhao Wang, Yipeng Wang, Jing Wang
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107165- (2023)
Summary: The risk of subsequent cerebrovascular disease among cancer patients of multiple cancers in the US is not well understood. A total of 3,843,261 cancer patients diagnosed from 1975 to 2018, were included from the surveillance, epidemiology, a
Externí odkaz:
https://doaj.org/article/cd7b66e55b974a46878c79b76b19fdb8
Autor:
Ke Zhang, Yuan Li, Xiangyi Kong, Chuqi Lei, Huaiyu Yang, Nianchang Wang, Zhongzhao Wang, Hu Chang, Lixue Xuan
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
AGR2 is a secreted protein widely existing in breast. In precancerous lesions, primary tumors and metastatic tumors, the expression of AGR2 is increased, which has aroused our interest. This review introduces the gene and protein structure of AGR2. I
Externí odkaz:
https://doaj.org/article/5a4135ea5a484eacb9838d6d5d2da91c
Autor:
Yan Lou, Yunyan Zhang, Zhongzhao Wang, Chenglong Zhao, Zhenxi Li, Quan Huang, Hao Tang, Jianru Xiao
Publikováno v:
Frontiers in Surgery, Vol 10 (2023)
ObjectiveLarge pneumothorax is a rare but dangerous complication following thoracic and lumbar tumor surgery. There is little discussion about the features of large pneumothorax following spinal tumor surgery. The purpose of this study was to analyze
Externí odkaz:
https://doaj.org/article/6e676839f232465880f2c66114fe5680
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Immune checkpoint inhibitors (ICIs) induce T-cell activation against cancer cells, and due to their anti-tumor function in multiple cancers, ICIs have been considered an important option for oncotherapy. PD-1/PD-L1 inhibitors are now widely used as I
Externí odkaz:
https://doaj.org/article/649d6d8a5555439ea53a4a1d63a331de
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Autoimmune diseases and malignant tumors are the two hotspots and difficulties that are currently being studied and concerned by the medical field. The use of PD-1/PD-L1 inhibitors improves the prognosis of advanced tumors, but excessive immune respo
Externí odkaz:
https://doaj.org/article/032644af7a0b47b19d64d974271d81c5