Zobrazeno 1 - 10 of 142 pro vyhledávání: '"Zhongyun Dong"'
1
Akademický článek
Additive effects of a small molecular PCNA inhibitor PCNA-I1S and DNA damaging agents on growth inhibition and DNA damage in prostate and lung cancer cells.
Autor: Shan Lu, Zhongyun Dong
Publikováno v: PLoS ONE, Vol 14, Iss 10, p e0223894 (2019)
Proliferating cell nuclear antigen (PCNA) is essential for DNA replication and repair, and cell growth and survival. Previously, we identified a novel class of small molecules that bind directly to PCNA, stabilize PCNA trimer structure, reduce chroma
Externí odkaz: https://doaj.org/article/f76167a805bc4f988ef22034756e3c81
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2
Akademický článek
Tiny Medicine: Nanomaterial-Based Biosensors
Autor: Nelson Watts, Mark J. Schulz, Chong H. Ahn, Laura Conforti, Dogyoon Kim, Joon-Sub Shim, Zhongyun Dong, Amit Bhattacharya, Yeo-Heung Yun, Edward Eteshola
Publikováno v: Sensors, Vol 9, Iss 11, Pp 9275-9299 (2009)
Tiny medicine refers to the development of small easy to use devices that can help in the early diagnosis and treatment of disease. Early diagnosis is the key to successfully treating many diseases. Nanomaterial-based biosensors utilize the unique pr
Externí odkaz: https://doaj.org/article/d2b93baf0ca0437a8a18af2916f56b9c
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4
Data from Targeted Overexpression of Vav3 Oncogene in Prostatic Epithelium Induces Nonbacterial Prostatitis and Prostate Cancer
Autor: Zhongyun Dong, Dianer Yang, Shan Lu, Linda Levin, Gregory Boivin, Qiande Hu, Jun Qin Mo, Yin Liu
Our previous study revealed that Vav3 oncogene is overexpressed in human prostate cancer, activates androgen receptor (AR), and stimulates growth in prostate cancer cells. The purpose of this study is to further determine the potential role of Vav3 i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a91d9eb50c4b906f37dc6a4117e3adf
https://doi.org/10.1158/0008-5472.c.6498122.v1
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8
Antiandrogen Therapy Radiosensitizes Androgen Receptor–Positive Cancers to (18)F-FDG
Autor: Indulekha Singaravelu, Zhongyun Dong, Mary C. Mahoney, Nalinikanth Kotagiri, Henry B. Spitz
Publikováno v: J Nucl Med
A subset (35%) of triple-negative breast cancers (TNBCs) expresses androgen receptor (AR) activity. However, clinical trials with antiandrogen drugs have shown limited efficacy, with about a 19% clinical benefit rate. We investigated the therapeutic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5995459c95c4bf2e602d0cfec753be5d
https://europepmc.org/articles/PMC9364347/
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9
Effect of Lithium and Aluminum on the Mechanical Properties, In Vivo and In Vitro Degradation, and Toxicity of Multiphase Ultrahigh Ductility Mg–Li–Al–Zn Quaternary Alloys for Vascular Stent Application
Autor: Daoli Zhao, William R. Heineman, Zhongyun Dong, Boeun Lee, Abhijit Roy, Raymon Yao, Prashant N. Kumta, Shauna Chen, Jingyao Wu
Publikováno v: ACS Biomaterials Science & Engineering. 6:1950-1964
Magnesium alloys are the most widely studied biodegradable metals for biodegradable vascular stent application. Two major issues with current magnesium alloy based stents are their low ductility and fast corrosion rates. Several studies have validate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f274df0e499fb899eaa0a2b0c9a7dd1e
https://doi.org/10.1021/acsbiomaterials.9b01591
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10
Visual Hydrogen Mapping Sensor for Noninvasive Monitoring of Bioresorbable Magnesium Implants In Vivo
Autor: Da-Tren Chou, Daoli Zhao, William R. Heineman, David J. Benson, William Hoagland, Zhongyun Dong, Prashant N. Kumta, Jingyao Wu
Publikováno v: JOM. 72:1851-1858
The biodegradation process of Mg alloys (LAZ611 and WKX41) has been monitored transdermally by using a visual H2 mapping sensor. The visual mapping sensor changes color from gray to dark blue upon exposure to H2 permeating through the skin generated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::314ed51bfce20506de91cdcfe6584eea
https://doi.org/10.1007/s11837-020-04052-4
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