Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Zhongwu Su"'
Autor:
Zhongwu Su, Yi Liu, Weijian Zhang, Wenhui Liang, Yuyan Chen, Jinyuan Cao, Yu Liu, Yiqing Zheng, Qi Li
Publikováno v:
Experimental Gerontology, Vol 189, Iss , Pp 112401- (2024)
Age-related hearing loss (ARHL) is the most common sensory disorder associated with human aging. Chronic inflammation is supposed to be an important contributor to ARHL. Yet, the underlying mechanisms of developing cochlear inflammation are still not
Externí odkaz:
https://doaj.org/article/e84c87cc8c7943d289e3614dd8aa0c99
Autor:
Weijian Zhang, Hao Xiong, Jiaqi Pang, Lan Lai, Zhongwu Su, Hanqing Lin, Bingquan Jian, Haidi Yang, Yiqing Zheng
Publikováno v:
Journal of Bio-X Research, Vol 2, Iss 2, Pp 81-86 (2019)
Abstract. Cisplatin (CDDP)-induced ototoxicity is one of the common adverse effects of cisplatin chemotherapy. Thus far, effective approaches for attenuating hearing loss are unavailable in clinical practice. Mitochondrial biogenesis acts as a master
Externí odkaz:
https://doaj.org/article/aacfa074db0842e6862ef2990df0f581
Publikováno v:
PeerJ, Vol 8, p e9737 (2020)
Background In our aging society, age-related hearing loss (AHL) is the most common sensory disorder in old people. Much progress has been made in understanding the pathological process of AHL over the past few decades. However, the mechanism of cochl
Externí odkaz:
https://doaj.org/article/fa9b419f403d44539af8903572381f06
Autor:
Zhian Ye, Zhongwu Su, Siyu Xie, Yuye Liu, Yongqiang Wang, Xi Xu, Yiqing Zheng, Meng Zhao, Linjia Jiang
Publikováno v:
eLife, Vol 9 (2020)
The sox2 expressing (sox2+) progenitors in adult mammalian inner ear lose the capacity to regenerate while progenitors in the zebrafish lateral line are able to proliferate and regenerate damaged HCs throughout lifetime. To mimic the HC damage in mam
Externí odkaz:
https://doaj.org/article/5ee414fb4d304d7c8c0d5aabfc0b79a2
Autor:
Hanqing Lin, Hao Xiong, Zhongwu Su, Jiaqi Pang, Lan Lai, Huasong Zhang, Bingquan Jian, Weijian Zhang, Yiqing Zheng
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Background: Mitochondrial dysfunction is considered to contribute to the development of age-related hearing loss (AHL). The regulation of mitochondrial function requires mitochondrial quality control, which includes mitophagy and dynamics. Dynamin-re
Externí odkaz:
https://doaj.org/article/9ddb56e792cf467790c0b4a53084b9f6
Autor:
Jiaqi Pang, Hao Xiong, Ting Zhan, Gui Cheng, Haiying Jia, Yongyi Ye, Zhongwu Su, Hongyu Chen, Hanqing Lin, Lan Lai, Yongkang Ou, Yaodong Xu, Suijun Chen, Qiuhong Huang, Maojin Liang, Yuexin Cai, Xueyuan Zhang, Xiaoding Xu, Yiqing Zheng, Haidi Yang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2019)
Cisplatin-induced ototoxicity is one of the major adverse effects in cisplatin chemotherapy, and hearing protective approaches are unavailable in clinical practice. Recent work unveiled a critical role of autophagy in cell survival in various types o
Externí odkaz:
https://doaj.org/article/a7cf60cb795d43c7936ab5c6f120acf9
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84486 (2013)
BACKGROUND:Rapidly growing evidence suggests that microRNAs (miRNAs) are involved in a wide range of cancer malignant behaviours including radioresistance. Therefore, the present study was designed to investigate miRNA expression patterns associated
Externí odkaz:
https://doaj.org/article/2b0cf67a732d42b9a63647b40a775459
Publikováno v:
BMC Neuroscience, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background There are currently no effective prediction methods for evaluating the occurrence of cognitive impairment in patients with cerebral small vessel disease (CSVD). Aims To investigate the risk factors for cognitive dysfunction in pat
Externí odkaz:
https://doaj.org/article/4ba6a8d00544455ea261c317ef50e124
Autor:
Wenhao Zhu, Xia Zhou, Mengmeng Ren, Wenwen Yin, Yating Tang, Jiabin Yin, Yue Sun, Xiaoqun Zhu, Zhongwu Sun
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Process approach is valuable for memory assessment in Alzheimer’s disease (AD) and mild cognitive impairment (MCI), yet its underlying mechanisms remain elusive. This study aims to synergize the process approach with brain struc
Externí odkaz:
https://doaj.org/article/44cc6efc1d6744a8be7473034a7efaef
Autor:
Bo Yu, Chunling Xu, Kaixiong Gao, Wenming Yang, Xin Wang, Zhongwu Sun, Bin Zhang, Zhihui Tang
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37991- (2024)
We conducted a study on the surface compound modification of shot peening and pure carbon DLC coating to simultaneously meet the requirements of wear resistance and fatigue resistance of spline structure. The effects of surface compound modification
Externí odkaz:
https://doaj.org/article/c0d8eade71734c5ab99e81a247ac8dc2