Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Zhongwen Lu"'
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-20 (2024)
Abstract Glycolysis-related metabolic reprogramming is a central hallmark of human cancers, especially in renal cell carcinoma. However, the regulatory function of glycolytic signature in papillary RCC has not been well elucidated. In the present stu
Externí odkaz:
https://doaj.org/article/8d65a860df014a44b775a0c8a6049c1a
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Renal cell carcinoma (RCC) is a prevalent and extensively immune-infiltrated malignancy of the urinary system. Immune cells play a crucial role in both the progression and therapeutic interventions targeting RCC. Nevertheless, the
Externí odkaz:
https://doaj.org/article/587c810b46c44876b780f3a98f695e01
Autor:
Dong Zhang, Kai Zhao, Tian Han, Xi Zhang, Xinchi Xu, Zhanpeng Liu, Xiaohan Ren, Xu Zhang, Zhongwen Lu, Chao Qin
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 269, Iss , Pp 115818- (2024)
A synthetic organic substance called bisphenol A (BPA) is used to make polyester, epoxy resin, polyacrylate, and polycarbonate plastic. BPA exposure on a regular basis has increased the risk of developing cancer. Recent research has shown that there
Externí odkaz:
https://doaj.org/article/c32fd9ff431d415e9d43f98ca64e2b93
Autor:
Kai Zhao, Dong Zhang, Xinchi Xu, Shangqian Wang, Zhanpeng Liu, Xiaohan Ren, Xu Zhang, Zhongwen Lu, Shancheng Ren, Chao Qin
Publikováno v:
Asian Journal of Urology, Vol 10, Iss 3, Pp 344-355 (2023)
Objective: The novel coronavirus (severe acute respiratory syndrome coronavirus 2) has been spreading worldwide since December 2019, posing a serious danger to human health and socioeconomic development. A large number of clinical trials have reveale
Externí odkaz:
https://doaj.org/article/7fab253bc1604927955804dc99e35fb8
Autor:
Fei Teng, Zhongwen Lu, Fei Gao, Jing Liang, Jiawen Li, Xuanhe Tian, Xianshuai Wang, Haowei Guan, Jin Wang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Depression is a common mental disease, with some patients exhibiting ideas and behaviors such as self-harm and suicide. The drugs currently used to treat depression have not achieved good results. It has been reported that metabolites produc
Externí odkaz:
https://doaj.org/article/7322cdba2ad14b5f8df3aa8ce864e635
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundClassical biomarkers have been used to classify clear cell renal cell carcinoma (ccRCC) patients in a variety of ways, and emerging evidences have indicated that cuproptosis is closely related to mitochondrial metabolism, thereby accelerati
Externí odkaz:
https://doaj.org/article/98d088af14de4aa0b45d5090025d6498
Autor:
Yelin Song, Baolian Song, Zhichao Yu, Andong Li, Lulu Xia, Yanwen Zhao, Zhongwen Lu, Zuowei Li
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 11, p 316 (2023)
Background: Copine 1 (CPNE1) acts as a promoter in the progression of many kinds of cancers with the exception of pancreatic cancer (PC). This research is designed to probe the function of the CPNE1-tumor necrosis factor receptor-associated factor 2
Externí odkaz:
https://doaj.org/article/cfba70da6d104661b22dfee3d9785287
Autor:
Yingqing Liu, Jiawei Wang, Lin Li, Haibo Qin, Yuang Wei, Xu Zhang, Xiaohan Ren, Wei Ding, Xudong Shen, Guangyao Li, Zhongwen Lu, Dong Zhang, Chao Qin, Lingsong Tao, Xinglin Chen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Extensive research indicates that tumor stemness promotes tumor progression. Nonetheless, the underlying roles of stemness-related genes in renal clear cell carcinoma (ccRCC) are unclear. Data used in bioinformatics analysis were downloaded
Externí odkaz:
https://doaj.org/article/0945a84cd6534481ad21062107d13f9e
Autor:
Dong Zhang, Xinchi Xu, Yuang Wei, Xinglin Chen, Guangyao Li, Zhongwen Lu, Xu Zhang, Xiaohan Ren, Shangqian Wang, Chao Qin
Publikováno v:
Cancer Control, Vol 29 (2022)
Objective Evidence shows that gene mutation is a significant proportion of genetic factors associated with prostate cancer. The DNA damage response (DDR) is a signal cascade network that aims to maintain genomic integrity in cells. This comprehensive
Externí odkaz:
https://doaj.org/article/f341cacb4d9643d8af9b72fc4bdd0eec
Autor:
Yanhua Wang, Lifeng Zhang, Hang Ren, Lijuan Ma, Jian Guo, Decai Mao, Zhongwen Lu, Lijun Lu, Dong Yan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Drosophila m6A writer complex regulates alternative splicing of the Sex-lethal gene. Here the authors show that a potential E3 ligase Hakai interacts with the fly m6A writer complex and that m6A level is reduced in Hakai mutant flies.
Externí odkaz:
https://doaj.org/article/5e0dc5d5e01143d99afed20b1554968e