Zobrazeno 1 - 10
of 253
pro vyhledávání: '"Zhongtao, Gai"'
Autor:
Zhe Yin, Chuan Zhang, Rui Dong, Xinyuan Zhang, Yingnan Song, Shengju Hao, Zhongtao Gai, Bingbo Zhou, Ling Hui, Shifan Wang, Huiqin Xue, Zongfu Cao, Yi Liu, Xu Ma
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-11 (2024)
Abstract Background Methylmalonic acidemia (MMA) is one of the most common hereditary organic acid metabolism disorders that endangers the lives and health of infants and children. Early detection and intervention before the appearance of a newborn
Externí odkaz:
https://doaj.org/article/cec8231e7f7046a1941835158df57573
Publikováno v:
Stem Cell Research, Vol 81, Iss , Pp 103554- (2024)
In this study, PBMCs used in reprogramming were from a boy suffered from AUTS2 syndrome confirmed by clinical and genetic diagnosis. iPSCs were established by non-integrated method, which carried AUTS2 heterozygous mutation. The established iPSCs pre
Externí odkaz:
https://doaj.org/article/d75815718efb4e5d834e84a1b135aa12
Autor:
Nannan Lou, Xiang Ma, Qingxin Luo, Xiaoling Wei, Yun Zhang, Jing Guo, Jing Wang, Zhongtao Gai
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 8, Pp n/a-n/a (2024)
Abstract Objective This retrospective longitudinal cohort study aimed to explore the best therapeutic regimen and treatment duration of cough variant asthma (CVA) in children. Methods A total of 314 children with CVA were divided into receive inhaled
Externí odkaz:
https://doaj.org/article/da36208415e947348d3ebbfa579e1a68
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33457- (2024)
Background: Dual occurrence of distinct genetic diseases is exceptionally rare, complicating both diagnosis and management when the conditions share overlapping symptoms. Case presentation: We describe a preschooler girl diagnosed with Down syndrome
Externí odkaz:
https://doaj.org/article/d2ac63f9ef984c0182046c64cd87839e
Gut microbiota-metabolite interactions meditate the effect of dietary patterns on precocious puberty
Autor:
Ying Wang, Chuandi Jin, Hongying Li, Xiangrong Liang, Changying Zhao, Nan Wu, Min Yue, Lu Zhao, Han Yu, Qian Wang, Yongsheng Ge, Meiling Huo, Xin Lv, Lehai Zhang, Guoping Zhao, Zhongtao Gai
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109887- (2024)
Summary: Precocious puberty, a pediatric endocrine disorder classified as central precocious puberty (CPP) or peripheral precocious puberty (PPP), is influenced by diet, gut microbiota, and metabolites, but the specific mechanisms remain unclear. Our
Externí odkaz:
https://doaj.org/article/fc2e7d1cec6a4c86b3d86514696d92b7
Publikováno v:
Stem Cell Research, Vol 77, Iss , Pp 103385- (2024)
Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (PIK3CD) gene (OMIM#602839) encodes the p110δ catalytic subunit, mainly expressed in immune cells, and is associated with autosomal dominant immunodeficiency-14A with lymphoprol
Externí odkaz:
https://doaj.org/article/e204d097cc8d42efba85eb687c8ae2b9
Publikováno v:
Stem Cell Research, Vol 77, Iss , Pp 103389- (2024)
Maturity-onset diabetes of the young type 2 (MODY2) is an autosomal dominant disorder caused by mutations in the GCK gene. It is characterized by a non-progressive slight increase in glycosylated hemoglobin (HbA1c), and mildly raised fasting glucose.
Externí odkaz:
https://doaj.org/article/81b56d438cbe484fbd0f8c89b3094a63
Publikováno v:
Stem Cell Research, Vol 77, Iss , Pp 103392- (2024)
Segawa syndrome, an autosomal recessive genetic disorder, arises from homozygous or compound heterozygous mutations in the TH gene. We established an induced pluripotent stem cell (iPSC) line from peripheral blood mononuclear cells (PBMCs) of an 4-mo
Externí odkaz:
https://doaj.org/article/ef9136ed7f31416788ef31c39bec46ba
Publikováno v:
Stem Cell Research, Vol 77, Iss , Pp 103381- (2024)
Congenital disorder of glycosylation (CDG) is inherited metabolic disease caused by defects in the genes important for the process of protein and lipid glycosylation. We established an induced pluripotent stem cell (iPSC) line from peripheral blood m
Externí odkaz:
https://doaj.org/article/92c83329db2d4ee5a1b8a16b987d3b3b
Autor:
Xia Lin, Mohnad Abdalla, Junjie Yang, Lei Liu, Yali Fu, Yanli Zhang, Shuchun Yang, Han Yu, Yongsheng Ge, Sufang Zhang, Guiyun Kang, Wei Dang, Qin Jiang, Ying Wang, Zhongtao Gai
Publikováno v:
BMC Pediatrics, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Sepsis is a life-threatening multiple-organ injury caused by disordered host immune response to microbial infection. However, the correlation between gut microbiota dysbiosis and immune indicators remains unexplored. To address this gap in k
Externí odkaz:
https://doaj.org/article/8346b05e5dab4c7a8f3993b4ea836f5e