Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Zhongquan Qi"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Cytosolic Glycerol-3-phosphate dehydrogenase 1 (GPD1, EC 1.1.1.8) plays a pivotal role in regulating the Embden-Meyerhof glucose glycolysis pathway (E-M pathway), as well as in conditions such as Huntington’s disease, cancer, and its poten
Externí odkaz:
https://doaj.org/article/1d748ee1fa5c43fdb0fcf4a717862acd
Autor:
Xia Qiu, Hedong Zhang, Zhouqi Tang, Yuxi Fan, Wenjia Yuan, Chen Feng, Chao Chen, Pengcheng Cui, Yan Cui, Zhongquan Qi, Tengfang Li, Yuexing Zhu, Liming Xie, Fenghua Peng, Tuo Deng, Xin Jiang, Longkai Peng, Helong Dai, Yuanyuan Ji
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 12, Pp 1453-1464 (2024)
Abstract. Background:. Homoharringtonine (HHT) is an effective anti-inflammatory, anti-viral, and anti-tumor protein synthesis inhibitor that has been applied clinically. Here, we explored the therapeutic effects of HHT in a mouse heart transplant mo
Externí odkaz:
https://doaj.org/article/f1c8744cb5b14f39a49dbb5d2d3abb65
Autor:
Yan Cui, Chao Chen, Zhouqi Tang, Wenjia Yuan, Kaiye Yue, Pengcheng Cui, Xia Qiu, Hedong Zhang, Tengfang Li, Xuejing Zhu, Jiadi Luo, Siyu Sun, Yaguang Li, Chen Feng, Longkai Peng, Xubiao Xie, Yong Guo, Yixin Xie, Xin Jiang, Zhongquan Qi, Angus W. Thomson, Helong Dai
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-14 (2024)
Abstract The triggering receptor expressed on myeloid cells 2 (TREM2) is an immune receptor that affects cellular phenotypes by modulating phagocytosis and metabolism, promoting cell survival, and counteracting inflammation. Its role in renal injury,
Externí odkaz:
https://doaj.org/article/5dcef436c25a4094a549c26ef22f7fa5
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
In this study, we explored the growing use of metal-organic framework (MOF)-based Nanozymes in biomedical research, with a specific emphasis on their applications in stroke therapy. We have discussed the complex nature of stroke pathophysiology, high
Externí odkaz:
https://doaj.org/article/917cda861d1f478cbcfecd88de0fd132
Autor:
Yiming Luo, Haijun Zhao, Jingtao Zhu, Liyi Zhang, Jie Zha, Li Zhang, Yi Ding, Xinyi Jian, Junjie Xia, Bing Xu, Zhongquan Qi
Publikováno v:
Cancer Medicine, Vol 12, Iss 18, Pp 18901-18917 (2023)
Abstract Background Acute myeloid leukemia (AML) is a highly aggressive form of cancer that is frequently diagnosed in adults and small molecule inhibitors have gained significant attention as a potential treatment option for AML. Methods The up‐re
Externí odkaz:
https://doaj.org/article/809e2f48da294fbcbb88558f9b8a1a87
Autor:
Dong Yu, Yue Mei, Ling Wang, Yunpeng Zhao, Xingfei Fan, Dong Liang, Li Li, Jie Zhu, Sisi Bi, Xue Wang, Zhongquan Qi, Lie Zhu, Yue Wang
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Background Extracellular vesicles (EVs) from human umbilical cord mesenchymal stem cells (hUMSCs) are widely considered to be the best mediators for cell-free therapy. An understanding of their composition, especially RNA, is particularly im
Externí odkaz:
https://doaj.org/article/47350a1c78174f898d7afd3a3432eb9f
Autor:
Muhammad Junaid, Hongyu Lu, Ahmad Ud Din, Bin Yu, Yu Liu, Yixiang Li, Kefei Liu, Jianhua Yan, Zhongquan Qi
Publikováno v:
Antibiotics, Vol 13, Iss 4, p 352 (2024)
Salmonella enterica serovar Typhimurium (S. Typhimurium), a foodborne pathogen that poses significant public health risks to humans and animals, presents a formidable challenge due to its antibiotic resistance. This study explores the potential of La
Externí odkaz:
https://doaj.org/article/457949a68326430aa9ed14028cdb1cb5
Autor:
Muhammad Junaid, Hongyu Lu, Yixiang Li, Yu Liu, Ahmad Ud Din, Zhongquan Qi, Yi Xiong, Jianhua Yan
Publikováno v:
Genes, Vol 15, Iss 4, p 435 (2024)
Salmonella typhimurium (S. typhimurium), a prevalent cause of foodborne infection, induces significant changes in the host transcriptome and metabolome. The lack of therapeutics with minimal or no side effects prompts the scientific community to expl
Externí odkaz:
https://doaj.org/article/ceff549057c846b1b281eea19ef1d396
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 614 (2024)
The treatment of spinal cord injury (SCI) is often ineffective. Additionally, SCI-induced inflammation leads to secondary injury. Current anti-inflammatory hydrophilic drugs fail to reach the nerve injury site due to the blood–brain barrier. Here,
Externí odkaz:
https://doaj.org/article/d0838c4b77c643b7aea6775af02f2afd
Autor:
Lumin Wang, Yanping Li, Dawei Yang, Jiazhao Fu, Bin Zhao, Yaguang Li, Yanrong Ye, Zhongquan Qi
Publikováno v:
Clinical and Translational Discovery, Vol 3, Iss 4, Pp n/a-n/a (2023)
Abstract Objects We conducted this study to confirm the immunosuppression effect of Deforolimus in heart allotransplantation and find its mechanism. Material and methods We used vitro methods to confirm the immunosuppression of Deforolimus in T cell
Externí odkaz:
https://doaj.org/article/555665e7defc47f98bbaa548d1210479