Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Zhongqiu Xie"'
Autor:
Lu Wang, Fang Sun, Qianying Li, Haojie Ma, Juanhong Zhong, Huihui Zhang, Siyi Cheng, Hao Wu, Yanmin Zhao, Nasui Wang, Zhongqiu Xie, Mingyi Zhao, Ping Zhu, Heping Zheng
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Therapeutic agents targeting cytokine-cytokine receptor (CK-CKR) interactions lead to the disruption in cellular signaling and are effective in treating many diseases including tumors. However, a lack of universal and quick access to annotat
Externí odkaz:
https://doaj.org/article/9b49570fc7b342f4ad08020003ae8945
Autor:
Qiong Wang, Bisheng Cheng, Sandeep Singh, Yiran Tao, Zhongqiu Xie, Fujun Qin, Xinrui Shi, Jingjing Xu, Chenxi Hu, Wanlong Tan, Hui Li, Hai Huang
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-15 (2024)
Abstract Circular RNAs (circRNAs) are a family of endogenous RNAs that have become a focus of biological research in recent years. Emerging evidence has revealed that circRNAs exert biological functions by acting as transcriptional regulators, microR
Externí odkaz:
https://doaj.org/article/346d0dc286dc4ecb8036985dd1befb8a
Autor:
Jun Li, Tao Huang, Jun Hua, Qiong Wang, Yang Su, Ping Chen, Scott Bidlingmaier, Allan Li, Zhongqiu Xie, Anil P. Bidkar, Sui Shen, Weibin Shi, Youngho Seo, Robert R. Flavell, Daniel Gioeli, Robert Dreicer, Hui Li, Bin Liu, Jiang He
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-13 (2023)
Abstract We recently identified CD46 as a novel prostate cancer cell surface antigen that shows lineage independent expression in both adenocarcinoma and small cell neuroendocrine subtypes of metastatic castration resistant prostate cancer (mCRPC), d
Externí odkaz:
https://doaj.org/article/dda216b0fc2a4b11a9340849cfc3ea50
Autor:
Qiong Wang, Junxiu Chen, Sandeep Singh, Zhongqiu Xie, Fujun Qin, Xinrui Shi, Robert Cornelison, Hui Li, Hai Huang
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Purpose Specific gene fusions and their fusion products (chimeric RNA and protein) have served as ideal diagnostic markers and therapeutic targets for cancer. However, few systematic studies for chimeric RNAs have been conducted in neuroendo
Externí odkaz:
https://doaj.org/article/175a9033af2043f2ab7ce97cb2ae0dd8
Autor:
Qiong Wang, Zean Li, Jin Yang, Shirong Peng, Qianghua Zhou, Kai Yao, Wenli Cai, Zhongqiu Xie, Fujun Qin, Hui Li, Xu Chen, Kaiwen Li, Hai Huang
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 8, Pp 1193-1210 (2022)
Objective: To explore the genetic changes in the progression of castration-resistant prostate cancer (CRPC) and neuroendocrine prostate cancer (NEPC) and the reason why these cancers resist existing therapies. Methods: We employed our CRPC cell line
Externí odkaz:
https://doaj.org/article/e5175525affb47fbb27777409b845396
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Arthropod pathogens and other microorganisms have been documented from mass production systems aimed at producing natural enemies for pest control. If losses due to pathogens are encountered in such systems, they could lead to uneconomical p
Externí odkaz:
https://doaj.org/article/0710341424c14538bd587d0eef43f2ec
Autor:
Zhongqiu Xie, Pawel Ł. Janczyk, Ying Zhang, Aiqun Liu, Xinrui Shi, Sandeep Singh, Loryn Facemire, Kristopher Kubow, Zi Li, Yuemeng Jia, Dorothy Schafer, James W. Mandell, Roger Abounader, Hui Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Genes that modulate the cytoskeleton have been associated with increased cell proliferation and migration. Here, the authors show that AVIL, an actin regulatory protein, is overexpressed in glioblastomas and mediates oncogenic effects through regulat
Externí odkaz:
https://doaj.org/article/03c59fd5f35148edbce45f1cfce5d926
Autor:
Ze Gao, Junxiu Chen, Yiran Tao, Qiong Wang, Shirong Peng, Shunli Yu, Jianwen Zeng, Kaiwen Li, Zhongqiu Xie, Hai Huang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Immunotherapy is gradually emerging in the field of tumor treatment. However, because of the complexity of the tumor microenvironment (TME), some patients cannot benefit from immunotherapy. Therefore, we comprehensively analyzed the TME and gene muta
Externí odkaz:
https://doaj.org/article/5317db73a2ef424abdb9359e9a950795
Autor:
Qiong Wang, Wanhua Wu, Ze Gao, Kaiwen Li, Shirong Peng, Huiyang Fan, Zhongqiu Xie, Zhenghui Guo, Hai Huang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
BackgroundChemoresistance is the major cause of death in advanced prostate cancer (PCa), especially in metastatic PCa (mPCa). However, the molecular mechanisms underlying the chemoresistance of PCa remain unclear. Understanding the reason behind the
Externí odkaz:
https://doaj.org/article/94e28f9337774abe9ccc3169173f8327
Autor:
Zhongqiu Xie, Hui Li
Publikováno v:
Molecular & Cellular Oncology, Vol 7, Iss 6 (2020)
Our work in rhabdomyosarcoma led us to the discovery of a novel oncogene, Advillin (AVIL) in glioblastoma. Multiple lines of evidence support that AVIL is an Achilles heel of glioblastoma, with its specific targeting potentially an effective treatmen
Externí odkaz:
https://doaj.org/article/a817be4e7c2744e1b70c18e5b7c4653d