Výsledky vyhledávání - "Zhongqi-Phyllis Wu"

Major histocompatibility complex class I-mediated inhibition of neurite outgrowth from peripheral nerves

Autor: Jide Tian, Zhongqi-Phyllis Wu, Daniel L. Kaufman, Terry Hsieh, Tina Bilousova, Hoa Dang, Nathalie Escande-Beillard

Publikováno v: Immunology Letters. 135:118-123

Studies of mice deficient in classical major histocompatability complex class I (MHCI) revealed that MHCI plays an important role in neurodevelopment in the central nervous system. We previously studied the effects of recombinant MHCI molecules on wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1dc41b609ba07020a7eb5a235844bd
https://doi.org/10.1016/j.imlet.2010.10.011

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Enhanced neuronal expression of major histocompatibility complex class I leads to aberrations in neurodevelopment and neurorepair

Autor: Hoa Dang, Jide Tian, Lorraine Washburn, Daniel L. Kaufman, Zhongqi-Phyllis Wu, Maia Boudzinskaia, Nathalie Escande-Beillard, Tina Bilousova, Cui-Wei Xie, Jyes Querubin

Publikováno v: Journal of neuroimmunology. 232(1-2)

Mice deficient in classical major histocompatibility complex class I (MHCI) have aberrations in neurodevelopment. The consequences of upregulated neuronal MHCI expression have not been examined. We found that transgenic C57Bl/6 mice that are engineer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0412c7ac6d5129601945637f2847bf1a
https://pubmed.ncbi.nlm.nih.gov/20950866

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Transgenic mice with enhanced neuronal major histocompatibility complex class I expression recover locomotor function better after spinal cord injury

Autor: Blake Middleton, Bonnie Wong, Nathalie Escande-Beillard, Hui Zhong, Hoa Dang, Jing Yong, Sharon Zdunowski, V. Reggie Edgerton, Daniel L. Kaufman, Niranjala J.K. Tillakaratne, Tina Bilousova, Maia Boudzinskaia, Zhongqi-Phyllis Wu, M. Selvan Joseph, Lorraine Washburn, Noore J. Ali

Publikováno v: Journal of neuroscience research. 89(3)

Mice that are deficient in classical major histocompatibility complex class I (MHCI) have abnormalities in synaptic plasticity and neurodevelopment and have more extensive loss of synapses and reduced axon regeneration after sciatic nerve transection

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4dfeb6f1345cc157d4d126672c03634
https://pubmed.ncbi.nlm.nih.gov/21259323

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Neurons preferentially respond to self-MHC class I allele products regardless of peptide presented

Autor: Lorraine Washburn, Christopher J. Evans, Hoa Dang, Blake Middleton, Dan Zekzer, Zhongqi-Phyllis Wu, Yoshitaka Yoshimura, Sebastian Joyce, Jide Tian, Shoshy Eitan, Sonja Ivkovic, Nathalie Escande-Beillard, Yuxin Lu, Daniel L. Kaufman, Tina Bilousova

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 184(2)

Studies of mice lacking MHC class I (MHC I)-associated proteins have demonstrated a role for MHC I in neurodevelopment. A central question arising from these observations is whether neuronal recognition of MHC I has specificity for the MHC I allele p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339ce98ee40eef76abef6a1c1a0ba883
https://pubmed.ncbi.nlm.nih.gov/20018625

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